Leonardo Zoccante
A5032164973- Autism Spectrum Disorder Research
- Child Nutrition and Feeding Issues
- Genetics and Neurodevelopmental Disorders
- Attention Deficit Hyperactivity Disorder
- COVID-19 and Mental Health
- Children's Physical and Motor Development
- Genomic variations and chromosomal abnormalities
- Obesity, Physical Activity, Diet
- Congenital heart defects research
- Family and Disability Support Research
- Diet and metabolism studies
- Obstructive Sleep Apnea Research
- Neuroscience of respiration and sleep
- Infant Development and Preterm Care
- Child and Adolescent Psychosocial and Emotional Development
- Birth, Development, and Health
- Human-Animal Interaction Studies
- Child Development and Digital Technology
- Obsessive-Compulsive Spectrum Disorders
- Fetal and Pediatric Neurological Disorders
- Adolescent and Pediatric Healthcare
- Chromosomal and Genetic Variations
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Infant Health and Development
- Psychological Well-being and Life Satisfaction
University of Verona
2008-2024
Azienda ULSS 9 TREVISO
2024
Azienda Ospedaliera Universitaria Integrata Verona
2011-2022
Charité - Universitätsmedizin Berlin
2022
Bridge University
2021
Regione del Veneto
2019
Moscow Research and Clinical Center for Neuropsychiatry
2018
University of Pavia
2010
University of Lausanne
1993
University of Trento
1991-1993
The 2019 coronavirus disease (COVID-19) outbreak could result in higher levels of psychological distress, especially among people suffering from pre-existing mental health conditions. Young individuals with autism spectrum disorders (ASD) are particularly at risk due to their vulnerability unpredictable and complex changes. This study aimed investigate the impact COVID-19 pandemic on ASD individuals, whether any pre-pandemic sociodemographic or clinical characteristics would predict a...
Background and objectives: Adolescence represents a critical period for rapid psychophysical socio-cognitive changes, with implications health wellbeing in later life. From this perspective, the manifestation of unhealthy lifestyles dysfunctional behaviors may reflect change requiring alertness prompt intervention. This study investigated lifestyle coping strategies among Italian adolescents, also relation to ongoing COVID-19 pandemic, whether they would predict subjective wellbeing....
In early 2020, a novel coronavirus (SARS-CoV-2) leading to potentially fatal condition was discovered. Since then, the 2019 disease (COVID-19) has spread worldwide becoming pandemic. Beyond risks strictly related infection, concerns have been expressed for psychological impact that COVID-19 may have, especially on vulnerable individuals with pre-existing mental health conditions. Somatic symptom disorder (SSD) is characterized by dysfunctional preoccupation physical symptoms excessive and...
In this study, we used deletions at 22q13, which represent a substantial source of human pathology (Phelan/McDermid syndrome), as model for investigating the molecular mechanisms terminal that are currently poorly understood. We characterized level genomic rearrangement in 44 unrelated patients with 22q13 monosomy resulting from simple (72%), ring chromosomes (14%), and unbalanced translocations (7%). also discovered interstitial between 17–74 kb 9% patients. Haploinsufficiency SHANK3 gene,...
Rare copy number variants (CNVs) disrupting ASTN2 or both and TRIM32 have been reported at 9q33.1 by genome-wide studies in a few individuals with neurodevelopmental disorders (NDDs). The vertebrate-specific astrotactins, its paralog ASTN1, key roles glial-guided neuronal migration during brain development. To determine the prevalence of astrotactin mutations delineate their associated phenotypic spectrum, we screened ASTN2/TRIM32 ASTN1 (1q25.2) for exonic CNVs clinical microarray data from...
Background/Objectives: Level 1 autism spectrum disorder (ASD) is a neurodevelopmental condition characterised by challenges in social and communication skills. Despite these difficulties, individuals with level ASD often exhibit average intelligence typical language development. Improving socialisation skills this population requires tailored approaches that address their specific needs include targeted strategies. This study aims to evaluate the effectiveness of structured training...
Maffeis C, Schena F, Zaffanello M, Zoccante L, Schutz Y, Pinelli L. Maximal aerobic power during running and cycling in obese non‐obese children. Acta Pædiatr 1994;83:113–16. Stockholm. ISSN 0803–5253 The maximal capacity while was measured 22 prepubertal children (mean age±SD 9.5 ± 0.8 years): 14 (47.3±10 kg) 8 (31.1±6.1 kg). Oxygen consumption (VO 2 ) carbon dioxide production were by an open circuit method. Steady state VO determined at different levels of exercise up to the on...
Abstract Objectives/Hypothesis: Auditory brainstem implants (ABIs) can provide excellent open set speech recognition in adults without auditory tumors. These favorable results prompted us to extend ABI indications children with profound hearing loss (HL) who are not candidates for a cochlear implant (CI). This article reports on the performance and cognitive development measured ABIs. Study Design: study quantifies of perceptual nonverbal abilities HL undergoing ABI. From 2000 2006, 17 aged...
COVID-19 pandemic may affect children's mental health. Children <18 years in-patiently admitted for health emergencies between March 2020 and June 2021 were compared to those in the same period of 2018-2019 terms sociodemographic clinical characteristics. There 49 admissions pre-pandemic 60 (IRR: 1.22; 95% CI: 0.84-1.79), with latter more likely have a family history psychiatric disorders, personal physical disturbances, present suicidal risk, being diagnosed an externalizing disorder. This...
The classical approach to autism spectrum disorders (ASD) is often limited considering their neuro-functional aspects. However, recent scientific literature has shown that ASDs also affect many body systems and apparatuses such as the immune system, sensory-motor gut-brain axis. connective tissue, a common thread linking all these structures, may have pathogenetic role in multisystem involvement of ASD. Depending on its different anatomical sites, tissue performs functions connection...
Pediatric obstructive sleep apnea can negatively affect children's neurocognitive function and development, hindering academic adaptive goals. Questionnaires are suitable for assessing neuropsychological symptoms in children with sleep-disordered breathing. The study aimed to evaluate the effectiveness of using Oxygen Desaturation Index compared Obstructive Apnea-Hypopnea predicting long-term consequences breathing children. We conducted a retrospective analysis respiratory polysomnography...
Equine-assisted activities and therapies (EAAT) have been suggested to improve adaptive behavior, possibly motor function, in autism spectrum disorder (ASD). This study investigated the effects of EAAT on behavior function 15 children with ASD (13 males) aged 7–15 years as well impact magnitude stress parent–child system evolution child interaction both trained therapist therapeutic animal through 20 weekly sessions EAAT. were associated greater coordination (all p ≤ 0.01) a progressive...
Although previous reports produced converging empirical evidence of a core deficit on visuospatial processing in children with nonverbal learning disability (NLD), few studies compared the profile individuals an autism spectrum disorder (ASD) or NLD visuoconstructive and working memory tasks. Nor did any these investigate role local bias, typically observed ASD, when comparing clinical groups. The present study aimed to analyze whether ASD share characteristics.A group participants (n = 17)...
The authors describe two unrelated individuals with fragile X syndrome (FXS) due to marked expansion and instability of the CGG trinucleotide repeats within mental retardation 1 gene (<i>FMR1</i>) periventricular heterotopia (PH). This observation suggests that <i>FMR1</i> is involved in neuronal migration abnormal migration, even beyond resolution MRI, contributes neurologic phenotype FXS.
Notwithstanding several research efforts in the past years, robust and replicable molecular signatures for autism spectrum disorders from peripheral blood remain elusive. The available literature on transcriptome ASD suggests that through accurate experimental design it is possible to extract important information disease pathophysiology at level. Here we exploit availability of a resource biomarkers ASD, Italian Autism Network (ITAN) collection, investigation transcriptomic based discordant...