A5072666029- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- Adolescent Sexual and Reproductive Health
- Sex work and related issues
- Global Maternal and Child Health
- Adipose Tissue and Metabolism
- Sodium Intake and Health
- Heart Failure Treatment and Management
- HIV Research and Treatment
- Glutathione Transferases and Polymorphisms
- HIV/AIDS Impact and Responses
- Hormonal Regulation and Hypertension
- Genomics, phytochemicals, and oxidative stress
- Diet and metabolism studies
- Renin-Angiotensin System Studies
- Migration, Health and Trauma
- Biochemical effects in animals
- Cardiovascular Disease and Adiposity
- Global Public Health Policies and Epidemiology
- Cardiac Fibrosis and Remodeling
- Peptidase Inhibition and Analysis
- Neurological Disorders and Treatments
- LGBTQ Health, Identity, and Policy
- Eicosanoids and Hypertension Pharmacology
- Nutritional Studies and Diet
Kyoto University
2014-2023
Kyoto Prefectural Institute of Public Health and Environment
2021
Kyoto University of Education
2020
Keio University Hospital
2003
Kanagawa Prefectural Hospital Organization
1992-2003
University of California, San Francisco
2003
Kobe City Nishi-Kobe Medical Center
2001
Kanagawa Cancer Center
1992-2000
Fondazione IRCCS Istituto Nazionale dei Tumori
2000
Toray (United States)
1998
Susceptibility to lung cancer may in part be attributable inter-individual variability metabolic activation or detoxification of tobacco carcinogens. The glutathione S-transferase M1 (GSTM1) genetic polymorphism has been extensively studied this context; two recent meta-analyses case-control studies suggested an association between GSTM1 deletion and cancer. At least 15 have published after these overviews. We undertook a new meta-analysis summarize the results 43 including >18 000...
To explore any association between the timing of initiation sexual activity and behaviors risks among university students in China. Data were derived from a cross-sectional study on behavior conducted Ningbo municipality, China, at end 2003. Students completed self-administered, structured questionnaire. Of 1981 sexually active male students, 1908 (96.3%) item for included bivariate trend analyses multiple logistic regression to compare this risks. Male early initiators had significantly...
Depression and anxiety symptoms are prevalent among university students in both developed developing settings. Recently, grit, defined as perseverance passion for long-term goals, has emerged an indicator of success well-being. However, the relationship between grit poor mental health outcomes is largely unknown. The current study investigates with depression Chiang Mai, Thailand.This cross-sectional was conducted from January to March 2018 aged 18-24 years Mai University, first largest...
Background Food insecurity is increasingly reported as an important barrier of patient adherence to antiretroviral therapy (ART) in both resource-poor and rich settings. However, unlike resource rich-settings, very few quantitative studies date have investigated the association food with ART Sub-Saharan Africa. The current study examines between among HIV-infected adults Democratic Republic Congo (DRC). Methods Findings This a cross-sectional patients receiving at three private one public...
Background Despite the pervasive use of smartphones among university students, there is still a dearth research examining association between smartphone and psychological well-being this population. The current study addresses gap by investigating relationship students in Thailand. Methods This cross-sectional was conducted from January to March 2018 aged 18–24 years largest Chiang Mai, primary outcome well-being, assessed using Flourishing Scale. Smartphone use, independent variable,...
Genes for cytochrome P4501A1 (CYP1A1) and glutathione S-transferase class mu (GSTM1) have been shown to be polymorphic, implicated in tobacco-related carcinogenesis. In the present study, role of combined genotypes CYP1A1 GSTM1 as a possible modulator smoking related lung cancers was studied relation tobacco smoke exposure level 118 Japanese patients aged <70 with squamous or small cell carcinomas lung. Among male patients, overall proportion null genotype (GSTM1[–] slightly higher than...
Abstract CYP1A1 is involved in the metabolism of benzopyrene, a suspected lung carcinogen; it therefore conceivable that genetically determined variations its activity modify individual susceptibility to cancer. The role MspI polymorphism cancer has been widely studied but not fully clarified. We have included 2,451 cases and 3,358 controls pooled analysis 22 case‐control studies on risk. found clear association between homozygous restriction fragment length (RFLP) risk Caucasians (age‐...
The global response to the HIV/AIDS epidemic has improved access antiretroviral therapy (ART) and contributed decreased morbidity mortality in sub-Saharan Africa. Patient adherence ART is crucial success of treatment. However, little known about determinants among people living with (PLWHA) Democratic Republic Congo (DRC). This qualitative study used in-depth semi-structured patient interviews, a purposive sampling strategy thematic analysis scheme identify barriers facilitators DRC. We...
Due to the rapid development of information and communication technologies, cyberbullying has emerged as a threat adolescents. This study aimed investigate prevalence correlates among profiles traditional bullying, cyberbullying, combined bullying Taiwanese high school students.This cross-sectional employed two-stage cluster sampling in Taipei City, Taiwan. In total, 2028 students completed an anonymous questionnaire between March May 2018. Nominal logistic regression analysis was performed,...
Backgrounds An estimated 2.5 million Afghans are living in the Iran and almost half of them young women at childbearing ages. Although evidence indicates lower rates antenatal care higher incidence pregnancy complications Afghan compared to Iranian women, underlying reasons not well defined. Therefore, present study, we aimed explore prevalence associated sociodemographic factors adverse outcomes examine impact intimate partner violence, food insecurity, poor mental health, housing issues on...
Abstract Background Intimate Partner Violence (IPV) is a serious public health issue and has been linked to range of adverse outcomes. This study explored the prevalence IPV its relationship with unmet need for family planning among sample married Afghan women aged 18–49 years. Methods used data from Afghanistan Demographic Health Survey (DHS) conducted in 2015. The relating IPV, planning, sociodemographic characteristics (n = 20,593) were extracted analyzed accounting sampling weights...
Recently, homozygous gene deletion of GSTM1, one the Mu class glutathione S-transferase isozymes, was found to occur in approximately half population various ethnic origins and has been implicated tobacco-related carcinogenesis. In present study we evaluated risk GSTM1 null genotype for lung cancer relation extent tobacco smoke exposure 178 patients (157 males, 21 females) 201 healthy controls (140 61 females), who were all Japanese current smokers aged ≤69 at time diagnosis. determined by...
To determine the prevalence and correlates of HIV-1 infection among community-based injecting drug users (IDUs) in Tehran, Iran.In October 2004, 213 IDUs were recruited from a drop-in center its neighboring parks streets Tehran. Participants interviewed using structured questionnaire regarding their sociodemographics HIV risk characteristics, specimens oral mucosal transudate collected tested for antibodies. Data analyzed chi multiple logistic regression to estimate odds ratios (OR) 95%...
This study was conducted to identify the prevalence of and potential risk factors for HIV-1 infection among drug users visiting treatment centers in Tehran, Iran.Cross-sectional quantitative study.Between October 2003 May 2004, who visited three public Tehran were interviewed information about their sociodemographics, use characteristics, incarceration history, sexual HIV/AIDS knowledge perception collected. Specimens oral mucosal transudate then collected from participants be tested...
The vulnerability of young people to HIV and the recent emergence epidemic in China have made it urgent assess update HIV/STD risk profile Chinese people. A self-administered questionnaire survey with cross-sectional design was conducted among 22,493 undergraduate students two universities Ningbo, China. Bivariate trend analysis multiple logistic regression were used compare sexual behaviors awareness between grades. Of respondents, 17.6% males 8.6% females reported being sexually active....
1. The basic mechanism underlying the structural vascular changes occurring in hypertension was studied cultured aortic smooth muscle cells (SMC) obtained by an explant method from spontaneously hypertensive rats (SHR) and stroke-prone SHR (SHRSP) compared with that normotensive Wistar--Kyoto (WKY) rats. 2. growth rate of SMC SHRSP at age 2.5--11 months greater than WKY even after repeated passages. 3. [3H]Thymidine [14C]leucine incorporation, ornithine decarboxylase (ODC) activity were...
Abstract Background Almost a third of Afghan women living in Iran are at childbearing age. Antenatal care (ANC) is an inextricable part healthy pregnancy and could prevent the adverse birth outcomes. 97% Iranian expectant receiving adequate ANC (4 or more visits). However, situation for pregnant unclear. Some studies indicated low access to among women. In present study, we aimed explore sociodemographic factors potential barriers associated with Iran. Methods A cross sectional study was...