A5083570149- Diabetes, Cardiovascular Risks, and Lipoproteins
- Lipoproteins and Cardiovascular Health
- Blood Pressure and Hypertension Studies
- Health disparities and outcomes
- Healthcare Systems and Reforms
- Health Promotion and Cardiovascular Prevention
- Global Public Health Policies and Epidemiology
- Nutrition and Health in Aging
- Cardiovascular Health and Risk Factors
- Health Systems, Economic Evaluations, Quality of Life
- Obesity, Physical Activity, Diet
- Global Health Care Issues
- Cancer, Lipids, and Metabolism
- Chronic Disease Management Strategies
- Nutritional Studies and Diet
- Colorectal Cancer Treatments and Studies
- Energy, Environment, Economic Growth
- Circular RNAs in diseases
- Neurological Disorders and Treatments
- Menopause: Health Impacts and Treatments
- Substance Abuse Treatment and Outcomes
- Diet, Metabolism, and Disease
- Obesity and Health Practices
- Adipokines, Inflammation, and Metabolic Diseases
- Alcohol Consumption and Health Effects
Chinese Academy of Medical Sciences & Peking Union Medical College
2019-2025
National Clinical Research
2021-2024
Peking Union Medical College Hospital
2021
Fudan University
2012-2013
To assess the different educational inequalities in mortality among generations born between 1940 and 1979 China, to investigate role of socioeconomic, behavioural, metabolic factors as potential contributors reduction inequalities.Nationwide, population based, prospective cohort study.The ChinaHEART (China Health Evaluation And risk Reduction through nationwide Teamwork) project all 31 provinces mainland China.1 283 774 residents aged 35-75 years, divided into four separate cohorts 1940s,...
The health significance of triglyceride-rich lipoproteins, also known as remnant cholesterol, has been increasingly recognized. However, evidence their associations with cause-specific mortality in the general population was previously insufficient. To explore these and heterogeneities across subgroups, a prospective cohort study conducted including 3,403,414 community-based participants from ChinaHEART, an ongoing government-funded public program throughout China, November 2014 through...
Importance Limited evidence supports the association between low-density lipoprotein cholesterol (LDL-C) and mortality across different atherosclerotic cardiovascular disease (ASCVD) risk stratifications. Objective To explore associations LDL-C levels to identify optimal ranges of with lowest in populations diverse ASCVD profiles. Design, Setting, Participants The ChinaHEART project is a prospective cohort study that recruited residents aged 35 75 years from 31 provinces mainland China...
Abstract Aim To determine the associations between Chinese visceral adiposity index (CVAI) and risks of all‐cause cause‐specific mortality. Materials Methods A total 3 916 214 adults were enrolled in a nationwide population cohort covering all 31 provinces mainland China. The CVAI was calculated based on age, body mass index, waist circumference, triglyceride high‐density lipoprotein cholesterol concentrations. We used Cox proportional hazards regression model to hazard ratios 95% confidence...
Abstract Background Healthy lifestyle behaviours are effective means to reduce the burden of diseases. This study was aimed fill knowledge gaps on distribution, associated factors, and potential health benefits mortality four healthy in China. Methods During 2015–2019, participants aged 35–75 years from 31 provinces were recruited by China PEACE Million Persons Project. Four investigated our study, including non-smoking, none or moderate alcohol use, sufficient leisure time physical activity...
Journal Article Cohort Profile: ChinaHEART (Health Evaluation And risk Reduction through nationwide Teamwork) Get access Runsi Wang, Wang National Clinical Research Center for Cardiovascular Diseases, NHC Key Laboratory of Medications, Fuwai Hospital, Chinese Academy Medical Sciences and Peking Union College, Beijing, People's Republic China Search other works by this author on: Oxford Academic PubMed Google Scholar Yang Yang, Jiapeng Lu, Lu Jianlan Cui, Cui Wei Xu, Xu Lijuan Song, Song...
The triglyceride-glucose (TyG) index has been recognized as a crucial risk factor for cardiovascular diseases. However, the association between TyG and mortality in general population remains elusive.
Background Characterizing and assessing the prevalence, awareness, treatment patterns of patients with isolated diastolic hypertension ( IDH ) can generate new knowledge highlight opportunities to improve their care. Methods Results We used data from China PEACE (Patient‐centered Evaluative Assessment Cardiac Events) Million Persons Project, which screened 2 351 035 participants aged 35 75 years between 2014 2018. was defined as systolic blood pressure <140 ≥90 mm Hg; awareness...
BackgroundHigh-density lipoprotein cholesterol (HDL-C) has been inversely associated with cardiovascular disease (CVD) risk, but recent evidence suggests that extremely high levels of HDL-C are paradoxically related to increased CVD incidence and mortality. This study aimed comprehensively examine the associations all-cause cause-specific mortality in a Chinese population.MethodsThe China Health Evaluation And risk Reduction through nationwide Teamwork (ChinaHEART) project included 3,397,547...
Background Evidence of socioeconomic status (SES)-related health inequality is scarce in patients with cardiovascular diseases (CVDs) who need both lifestyle change and medical care, particularly developing countries. Methods The study employed a nationwide population-based cohort design, covering all 31 provinces Chinese mainland from September 2014 to March 2021. Participants aged 35–75 years self-reported CVD diagnoses were included. Information on SES details collected via questionnaire,...
The body mass index (BMI), as an easy-to-calculate measure of fatness, is closely associated with all-cause mortality, but few studies a large enough scale have examined the relationship between BMI and quality life. A comprehensive precise insight into new range needed. Based on ChinaHEART (Health Evaluation And risk Reduction through nationwide Teamwork), nationwide, population-based cohort study, 4,485,773 participants living in 20,159 communities or villages were passively followed for...
China has been undergoing a rapid urbanisation. There are substantial disparities between old and new urban citizens in access to health care. We aimed compare cardiovascular disease prevention death risks among four distinct groups.Urban residents aged 35-75 years living 96 prefecture-level cities from 31 provinces mainland were enrolled the national population-based cohort Patient-centered Evaluative Assessment of Cardiac Events Million Persons Project. They categorised into groups by...
Since 2010, China has made vast financial investments and policy changes to the primary care system. We aimed assess how hypertension awareness, treatment, control might be used quality of systems, which reflect outcomes public health services medical care.We The Patient-centred Evaluative Assessment Cardiac Events Million Persons Project, a government-funded project that focuses on cardiovascular disease risk in China. linked institution characteristics were captured survey between 2016...
To examine the joint association of healthy lifestyles and statin use with all-cause cardiovascular mortality in high-risk individuals, evaluate survival benefits by life expectancy.
Objectives We aimed to assess the dose–response association between weight gain from young middle adulthood and odds of metabolic syndrome, across body mass index (BMI) categories at adulthood. Methods Based on a national population-based screening project, middle-aged (35–64 years) participants who recalled age 25 years received standardized measurements were included. Multivariable adjusted restricted cubic splines logistic regression models applied. Results In total, 437,849 included...
Lipid-lowering therapy (LLT) is one of the key strategies for reducing atherosclerotic cardiovascular disease (ASCVD) burden. However, little known about percentage people in need different LLT regimens to achieve optimal targets low-density lipoprotein cholesterol (LDL-C), and corresponding cost benefit.We conducted a simulation study based on data from nationwide China PEACE MPP population cohort (2015-2020), which we included 2,904,914 participants aged 35-75 years all 31 provinces...
Abstract Aims We aimed to demonstrate the distribution of alcohol use disorder (AUD) in China and assess its association with quality life mortality. Methods studied 367 120 men aged 35–75 years from 31 provinces Patient-Centered Evaluative Assessment Cardiac Events (PEACE) Million Persons Project. At baseline, AUD was assessed by disorders identification test score, EQ-5D-3L questionnaire used measure life. Mortality data collected via National Surveillance System Vital Registration. Mixed...
The association and its population heterogeneities between low-density lipoprotein cholesterol (LDL-C) all-cause cardiovascular mortality remain unknown. We aimed to examine the dose-dependent associations of LDL-C levels with specific types disease (CVD) in among different subgroups.
Background Knowledge gaps remain in how gender-related socioeconomic inequality affects sex disparities cardiovascular diseases (CVD) prevention and outcome. Methods Results Based on a nationwide population cohort, we enrolled 3 737 036 residents aged 35 to 75 years (2014-2021). Age-standardized differences the effect of (Gender Inequality Index) were explored 9 CVD indicators. Compared with men, women had seemingly better primary (aspirin usage: relative risk [RR], 1.24 [95% CI, 1.18-1.31]...