A5085105154- Functional Brain Connectivity Studies
- Treatment of Major Depression
- Mental Health Research Topics
- Resilience and Mental Health
- Neural dynamics and brain function
- COVID-19 and Mental Health
- Tryptophan and brain disorders
- Grit, Self-Efficacy, and Motivation
- EEG and Brain-Computer Interfaces
- Personality Disorders and Psychopathology
- Healthcare Systems and Public Health
- Psychotherapy Techniques and Applications
- Diabetes Management and Education
- Attention Deficit Hyperactivity Disorder
- Maternal Mental Health During Pregnancy and Postpartum
- Intensive Care Unit Cognitive Disorders
- Advanced Neuroimaging Techniques and Applications
- Assisted Reproductive Technology and Twin Pregnancy
- Advanced MRI Techniques and Applications
- Ovarian function and disorders
- Sperm and Testicular Function
- Child and Adolescent Psychosocial and Emotional Development
- Stress Responses and Cortisol
- Neurotransmitter Receptor Influence on Behavior
- Traditional Chinese Medicine Studies
Shanxi Medical University
2008-2024
Second Xiangya Hospital of Central South University
2019-2023
Central South University
2019-2023
Hunan Institute of Mental Health
2020-2023
Altered resting-state EEG activity has been repeatedly reported in major depressive disorder (MDD), but no robust biomarkers have identified until now. The poor consistency of alterations may be due to inconsistent resting conditions; that is, the eyes-open (EO) and eyes-closed (EC) conditions. Here, we explored effect EO EC conditions on for discriminating MDD subjects healthy control (HC) subjects. data were recorded from 30 first-episode 26 HC during an 8-min session. features extracted...
Background: The difficulty in timely evaluating patient response to antidepressants has brought great challenge the treatment of major depressive disorder (MDD). Some studies found that electroencephalogram (EEG) microstates might be a reliable marker evaluate treatment. present study aims relationship between EEG microstate parameters and MDD symptoms before after identify predictive biological markers for response. Methods: Thirty drug-naïve patients (20 females 10 males) were enrolled...
Background: Major depressive disorder (MDD) is associated with a wide range of cognitive deficits. However, it remains unclear whether there will be major deficit independently caused by depression at acute episodes MDD. Methods: A comprehensive neurocognitive test battery was used to assess the executive function, processing speed, attention and memory in 162 MDD patients 142 healthy controls (HCs). multivariate analysis variance, hierarchical regression analyses general linear were explore...
Treatment non-response and recurrence are the main sources of disease burden in major depressive disorder (MDD). However, little is known about its neurobiological mechanism concerning brain network changes accompanying pharmacotherapy. The present study investigated intrinsic networks during 6-month antidepressant treatment phase associated with response MDD.Resting-state functional magnetic resonance imaging was acquired from untreated patients MDD healthy controls at baseline. patients'...
Even with continuous antidepressant treatment, residual symptoms and the risk of relapse can persist in remitted major depressive disorder (MDD) patients. Hence, having a clear recognition persistent abnormalities underlying neural substrate MDD through longitudinal investigation is great importance.A total 127 adult medication-free patients an acute episode 118 matched healthy controls (HCs) underwent diffusion tensor imaging. Over 6-month treatment course, 62 second scan. Remission was...
Introduction Major depressive disorder (MDD) is associated with low-grade inflammation, and anti-inflammatory treatment can help improve symptoms. A recent study found that fluvoxamine (FLV) reduce Interleukin-6 (IL-6) production via sigma-1 receptor in inflammation models. However, the anti- IL-6 effect of FLV treating patients MDD whether it contribute to antidepressant effects remain unclear. Methods total 65 34 healthy controls were recruited at baseline, 50 completed for 2 months. We...
Abstract Background Academic emotion is a fundamental emotional concept closely linked to academic achievement. Understanding the connection between and personality trait of hardiness pivotal in maintaining stable career orientation throughout one's educational career. Therefore, pursuit fostering robust growth nursing careers, it imperative delve into emotions experienced by undergraduate students. This study endeavors mitigate impact gender differences among students while investigating...
Varicoceles are a common cause of male infertility, affecting up to 35% men undergoing fertility evaluations. This study aims investigate the potential influence altitude and residence time on occurrence varicoceles, as well sperm quality sterility in plateau areas. A total 168 patients with varicocele were enrolled study, population was divided into groups based their direct exposure different high altitudes due living locations. The internal diameter Quiet breath (Dr), Valsalva maneuver...
To investigate the cognitive ability and coping strategy to mental disorders among medical workers in ear-nose-throat departments its impact on doctor-patient relationship. Methods: A total of 78 (including doctors, nurses, technicians) from 10 general hospitals Hunan Province were investigated by self-compiled questionnaire perspective workers. Results: Mental except depression schizophrenia poorly understood respondents, many their strategies inappropriate. Furthermore, subjects tend avoid...
Abstract Background : Academic emotion is a fundamental emotional concept closely linked to academic achievement. Understanding the connection between and personality trait of hardiness pivotal in maintaining stable career orientation throughout one's educational journey. Therefore, pursuit fostering robust growth nursing careers, it imperative delve into emotions experienced by undergraduate students. This study endeavors mitigate impact gender differences among students while investigating...