A5008109892- Pelvic floor disorders treatments
- Anorectal Disease Treatments and Outcomes
- Colorectal Cancer Surgical Treatments
- Peripheral Neuropathies and Disorders
- Hereditary Neurological Disorders
- Cell Adhesion Molecules Research
- Angiogenesis and VEGF in Cancer
- Pain Mechanisms and Treatments
- Gastric Cancer Management and Outcomes
- Congenital gastrointestinal and neural anomalies
- Atomic and Subatomic Physics Research
- Myasthenia Gravis and Thymoma
- Radiation Therapy and Dosimetry
- Peripheral Nerve Disorders
- Hernia repair and management
- Lanthanide and Transition Metal Complexes
- Colorectal and Anal Carcinomas
- Urinary Bladder and Prostate Research
- Cancer, Stress, Anesthesia, and Immune Response
- Receptor Mechanisms and Signaling
- Surgical site infection prevention
- Stoma care and complications
- Adolescent and Pediatric Healthcare
- Caveolin-1 and cellular processes
- Digital Imaging in Medicine
Humboldt-Universität zu Berlin
2024
Charité - Universitätsmedizin Berlin
2005-2024
Freie Universität Berlin
2004-2024
St. Josef-Hospital
2001-2021
Ruhr University Bochum
2020-2021
Objective. To study the efficacy and safety of botulinum toxin type A (BtxA) in treatment upper limb muscle spasticity, caused by stroke. Methods. This was a randomized, controlled trial. Patients received either placebo injections or total 1000 IU BtxA (Dysport) into five muscles affected arm. Muscle tone assessed using Modified Ashworth Scale (MAS). Other outcome measures were change joint range motion (ROM), Barthel index, pain score, goal attainment subjective evaluation benefit patients...
Background: Mesenchymal to epithelial transition factor (MET) dysregulation in non-small-cell-lung-cancer (NSCLC) is understudied, with scant data on treatment outcomes. Methods: We retrospectively examined 160 NSCLC patients: 125 primary MET mutations (further classified into exon 14 (METex14) skipping and amplifications) 35 secondary amplifications. Patients underwent varied treatments: Chemotherapy, Immune monotherapy, Crizotinib, or Savolitinib. Secondary amplification patients were...
Background: Up to 20% of patients with chronic immune-mediated sensorimotor neuropathies (CIN) do not respond adequately first-line therapies. However, studies on further treatment are scarce. Methods: We analyzed retrospectively 200 CIN regarding disease characteristics and response therapy cyclophosphamide (CYP), rituximab (RTX), bortezomib (BTZ). Treatment was defined as improvement or stabilization inflammatory neuropathy cause overall disability score (INCAT-ODSS). Results: A total 48...
Abstract Objective To evaluate the European Federation of Neurological Societies (EFNS)/Peripheral Nerve Society (PNS) diagnostic criteria for chronic inflammatory demyelinating polyneuropathy (CIDP) in a cohort patients diagnosed and treated CIDP tertiary university hospital. Methods In monocentric retrospective study 203 patients, according to expert opinion, we evaluated EFNS/PNS criteria. Clinical course nerve conduction studies (NCS) over 1 year from first referral were studied....
Background and purpose Monitoring of the disease course patients with chronic inflammatory demyelinating polyneuropathy (CIDP) remains challenging because nerve conduction studies do not adequately correlate functional disability. The prognostic value pathological spontaneous activity (PSA) in needle electromyography (EMG) different CIDP subgroups a longitudinal context has, to date, been analysed. We aimed determine whether PSA was marker or cohort CIDP. Methods A total 127 spectrum...
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Background: For locally advanced rectal cancer, neoadjuvant therapy (NT) is an established element of therapy. Endoscopic vacuum (EVT) has been a relevant treatment option for anastomotic leakage after resection since 2008. The aim was to evaluate the influence NT on duration and success EVT in cancer. Methods: This monocentric, retrospective cohort study including patients who underwent with primary anastomosis because histologically proven carcinoma rectum Department General Visceral...
Introduction: Established biomarkers for predicting chemoradiotherapy efficacy limited-disease small cell lung cancer (LD-SCLC) are lacking. The inflammation-based Glasgow Prognostic Score (GPS), comprising serum C-reactive protein (CRP) and albumin levels, can predict survival in advanced cancer. This study investigated whether metabolic inflammatory markers, including the GPS, of patients with LD-SCLC. Methods: We retrospectively analyzed 124 who underwent LD-SCLC at two institutions...
Introduction: Established biomarkers for predicting chemoradiotherapy efficacy limited-disease small cell lung cancer (LD-SCLC) are lacking. The inflammation-based Glasgow Prognostic Score (GPS), comprising serum C-reactive protein (CRP) and albumin levels, can predict survival in advanced cancer. This study investigated whether metabolic inflammatory markers, including the GPS, of patients with LD-SCLC. Methods: We retrospectively analyzed 124 who underwent LD-SCLC at two institutions...
Zusammenfassung Bisphosphonate spielen eine entscheidende Rolle in der Osteologie und Onkologie. Sie vermindern die Häufigkeit unerwünschter skelettaler Ereignisse verbessern somit Lebensqualität Patienten. Bis phosphonate gelten insgesamt als nebenwirkungsarm. Doch seit Beschreibung Bisphosphonat-assoziierter Kiefernekrosen haben sich diese zu einem ernsthaften klinischen Problem entwickelt. treten hauptsächlich bei Patienten mit langjähriger intravenöser Applikation von stickstoffhaltigen...
Dieser Beitrag gibt einen Überblick über die Besonderheiten der radiologischen Diagnostik von Frakturen im Kindesalter. Nach einer einleitenden Darstellung Skelettentwicklung wird auf röntgenologische eingegangen. Zusätzlich werden weiterführende bildgebende Verfahren wie Sonographie, CT und MRT diskutiert. Es dargestellt, wann diese Methoden zu schnellen genaueren Diagnosefindung beitragen, nachdem projektionsradiographisch keine befriedigende Diagnose möglich war. kurzen Beschreibung...