A5024677686- Acute Myeloid Leukemia Research
- Colorectal Cancer Treatments and Studies
- Hematopoietic Stem Cell Transplantation
- Wireless Communication Networks Research
- Advanced Wireless Communication Techniques
- Lung Cancer Treatments and Mutations
- Gastric Cancer Management and Outcomes
- Retinoids in leukemia and cellular processes
- Mesenchymal stem cell research
- Multiple Myeloma Research and Treatments
- Central Venous Catheters and Hemodialysis
- Pancreatic and Hepatic Oncology Research
- Viral-associated cancers and disorders
- Lymphoma Diagnosis and Treatment
- Cancer Genomics and Diagnostics
- RNA Interference and Gene Delivery
- Polyomavirus and related diseases
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cytomegalovirus and herpesvirus research
- Cardiac tumors and thrombi
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Renal cell carcinoma treatment
- Optical Imaging and Spectroscopy Techniques
- Bone health and osteoporosis research
- Photodynamic Therapy Research Studies
Bucheon University
2014-2023
Soonchunhyang University
2014-2023
Soonchunhyang University Hospital
2009-2023
BioMarin (United States)
2022
Washington University in St. Louis
2013
Korea National Tuberculosis Association
2013
Catholic University of Korea
2008
Mississippi State University
2004-2006
Soon Chun Hyang University Cheonan Hospital
2006
Sun Moon University
2006
We investigated clinical efficacy of green tea extracts (polyphenon E; poly E and (−)-epigallocatechin-3-gallate [EGCG]) delivered in a form ointment or capsule patients with human papilloma virus (HPV) infected cervical lesions. Fifty-one lesions (chronic cervicitis, mild dysplasia, moderate dysplasia severe dysplasia) were divided into four groups, as compared 39 untreated control. Poly was applied locally to 27 twice week. For oral delivery, 200 mg EGCG taken orally every day for eight 12...
Recombinant adeno-associated virus (rAAV) vectors are often produced in HEK293 or Spodoptera frugiperda (Sf)-based cell lines. We compared expression profiles of "oversized" (∼5,000 bp) and "standard-sized" (4,600 rAAV5-human α1-antitrypsin (rAAV5-hA1AT) manufactured Sf cells investigated molecular mechanisms mediating decline. C57BL/6 mice received 6 × 1013 vg/kg vector, blood liver samples were collected through week 57. For all vectors, peak (weeks 12-24) declined by 50% to Sf-...
Ride comfort is one of the most important dynamic performance characteristics railway vehicles and affected by various factors, such as vibration, acoustic sound, smell, temperature, visual stimuli, humidity seat design. In general, vibration known to be a major factor that affects ride comfort. There are many studies on methods for evaluating in vehicles, standards or criteria have been developed used countries. Most evaluation methods, however, recommend different criteria, so users should...
This study investigated the safety and effectiveness of each type central venous catheters (CVC) in patients with cancer. We prospectively enrolled cancer who underwent catheterization involving a subclavian catheter (SVC), peripherally inserted (PICC), or chemo-port (CP) our department. From March 2007 to 2009, 116 179 episodes catheterization. A SVC was most frequently (46.4%). Fifty-four complications occurred (30.1%): infection 23 cases, malpositioning migration tip 18 thrombosis eight...
We investigated the role of fasting hormones and pro-inflammatory cytokines in cancer patients. Hormones (ghrelin, adiponectin, leptin) (TNF-α, IFN-γ, IL-6) were measured by ELISA or RIA lung colorectal patients before administration therapy, measurements repeated every 2 months for 6 months. From June 2006 to August 2008, 42 (19 with 23 cancer) enrolled. In total, 21 included cachexia group others served as a comparison group. No significant difference initial ghrelin, TNF-α, IL-6 level was...
Purpose The prognosis of gastric cancer patients with bone marrow metastases is extremely poor. current study was conducted to evaluate the clinical outcomes advanced metastases. Materials and Methods We retrospectively reviewed medical records 26 who were treated at Soonchunhyang University Hospital between September 1986 February 2009. Results median age 46 years (range, 24 61 years). All had poorly differentiated adenocarcinoma, including 17 signet ring cell carcinomas. majority...
We propose a multicarrier code-division multiple-access (MC-CDMA) system employing an antenna array at the base station, and analyze performance of MC-CDMA in fading channel. An optimal beamformer not requiring explicit direction arrival estimation or training signals is derived for reverse link, shown to reduce interferences from other users significantly, thus increasing system's user capacity. Also, it that approach can achieve better than direct-sequence CDMA when both approaches employ...
The fetal liver kinase 1 (FLK-1)(+) hemangioblast can generate hematopoietic, endothelial, and smooth muscle cells (SMCs). ER71/ETV2, GATA2, SCL form a core transcriptional network in development. Transient coexpression of these three factors during mesoderm formation stage mouse embryonic stem (ESCs) robustly enhanced generation by activating bone morphogenetic protein (BMP) FLK-1 signaling while inhibiting phosphatidylinositol 3-kinase, WNT signaling, cardiac output. Moreover, etsrp,...
We experienced a case of primary renal synovial sarcoma in 32 year-old woman. On admission, she complained intermittent abdominal pain. radiologic examination, 12×10 cm-sized soft tissue mass was detected on the left kidney. The tumor had histologic and immunophenotypic features that were consistent with spindle cell type monophasic sarcoma. Four months after complete resection tumor, unilateral hematogenous metastasis developed lung. She treated combined chemotherapy doxorubicin ifosfamide...
The COVID-19 pandemic is changing rapidly and requires different strategies to maintain immunization. In Korea, vaccines are recommended available for various populations, including healthcare workers (HCWs) at high risk of SARS-CoV-2 infection. We plan evaluate the adverse events (AEs) immunogenicity BNT162b2 ChAdOx1 in HCWs a single center. This cohort study included fully vaccinated with either or ChAdOx1. Blood samples were taken eight weeks after second vaccination both six months from...
A 65-yr-old woman presented 17 yr status post-hysterectomy with bilateral ovarian salpingo-oophorectomy, attributable to cancer. She was admitted our hospital, multiple cystic liver masses and large seeded in her abdomen pelvic cavity. Histological examination of the demonstrated granulosa cell tumors. After two courses systemic combination chemotherapy, paclitaxel carboplatin, cavity increased, debulking surgery also failed because peritoneal dissemination severe adhesion. Finally, she...
Stroke is a major cause of long-term disability world-wide. Limited pharmacological therapy has been used in stroke patients. Previous studies indicated that herb formula PM012 neuroprotective against neurotoxin trimethyltin rat brain, and improved learning memory animal models Alzheimer’s disease. Its action not reported. This study aims to determine PM012-mediated neural protection cellular stroke. Glutamate-mediated neuronal loss apoptosis were examined primary cortical cultures. Cultured...
Purpose This phase II clinical trial was conducted to evaluate the activity and safety of a combination treatment paclitaxel (Genexol®) plus carboplatin in patients with advanced non-small cell lung cancer. Materials Methods Chemotherapy-naïve having histologically confirmed or metastatic cancer were enrolled. Genexol® administered at 225 mg/m2 intravenous (IV) infusion over 3 hours, followed by (area under concentration-time curve=6) IV on day 1 every weeks. Results Twenty-eight enrolled...
The efficacy of epidermal growth factor (EGF) receptor (EGFR) inhibitors in patients with non-small cell lung cancer (NSCLC), pancreatic (PC), or colorectal (CRC) has been demonstrated. However, dermatological reactions to these can cause significant physical and psychosocial discomfort. objective the present study was evaluate EGF ointment for EGFR inhibitor-related skin adverse events (ERSEs).
Extramedullary plasmacytoma of the liver is a very rare tumor.Although few cases extramedullary have been reported, we could not find any report on truly localized in literature.The patient was 63-yr-old man who exhibited solitary mass dynamic computed tomography and magnetic resonance imaging.Histologically, tumor composed mature plasma cells with mild atypia.Immunohistochemistry demonstrated monoclonal IgG Kappa light chain expression.Bone marrow examination revealed no abnormalities.There...
Human CD34+ Cells Engraftment in a Dose-dependent Fashion NOD/SCID Mice Mesenchymal stem cells (MSCs) have recently been identified and characterized humans.Moreover, MSC secrete cytokines that can support hematopoietic progenitor growth.In the present study, we evaluated whether efficacy of cell transplantation is improved by their co-transplantation with MSC, this positively correlated dose infused MSCs.Accordingly, irradiated mice were transplanted 1× ×10 5 human presence or absence...
Purpose We retrospectively determined the efficacy and safety of combination oxaliplatin, 5-fluorouracil (5-FU), folinic acid (FA) as first-line chemotherapy for patients with metastatic or recurrent gastric cancer. Materials Methods Between January 2006 August 2009, 39 histologically-confirmed, cancer underwent chemotherapy, results were investigated. The regimen consisted oxaliplatin (100 mg/m2) FA (200 mg/m2; 2-hour infusion), then 5-FU (2,400 46-hour continuous infusion) every 2 weeks....
In this study, we examined the efficacy and toxicity of S-1 with cisplatin as a second-line palliative chemotherapy for gemcitabine-refractory pancreatic cancer patients. Patients who had been previously treated gemcitabine-based first-line received S-1/cisplatin [body surface area (BSA) <1.25 m2 , 40 mg/day; BSA ≤1.25 to <1.5 m2, 50 ≥1.5 60 mg/day, orally, bid, daily on days 1-14 followed by 7-day washout mg/m2/day intravenously day 1] every three weeks. The enrollment 32 patients was...
Erlotinib has been the only targeted agent to show significantly improved outcomes in pancreatic adenocarcinoma when combined with gemcitabine. We aimed evaluate whether addition of oxaliplatin a combination gemcitabine/erlotinib treatment conferred clinical benefit patients locally advanced unresectable or metastatic cancer.Chemotherapy-naïve cancer were randomly assigned receive GEMOX-T [gemcitabine 1000 mg/m² and 50 on day 1 (D1) D8 plus erlotinib 100 mg daily for 3 weeks] GT (gemcitabine...