A5101520179- MicroRNA in disease regulation
- Circular RNAs in diseases
- Cancer-related molecular mechanisms research
- Cancer, Stress, Anesthesia, and Immune Response
- Single-cell and spatial transcriptomics
- Extracellular vesicles in disease
- Nanoplatforms for cancer theranostics
- Plant Water Relations and Carbon Dynamics
- Horticultural and Viticultural Research
- Aldose Reductase and Taurine
- Molecular Biology Techniques and Applications
- RNA Interference and Gene Delivery
- Biological and pharmacological studies of plants
- Cancer Genomics and Diagnostics
- Computational Drug Discovery Methods
- Bioactive natural compounds
- Immune cells in cancer
- Prenatal Substance Exposure Effects
- Plant responses to elevated CO2
- GDF15 and Related Biomarkers
- Retinoids in leukemia and cellular processes
- Macrophage Migration Inhibitory Factor
- Autophagy in Disease and Therapy
- Chromatography in Natural Products
- Microbial Metabolism and Applications
Shanghai Jiao Tong University
2022-2024
Renji Hospital
2024
Liuzhou General Hospital
2022-2023
Nankai University
2023
Shanxi Agricultural University
2021-2022
State Key Laboratory of Oncogene and Related Genes
2022
Cuproptosis, a copper-dependent cell death process, has been confirmed to further activate the immune response and mediate resistance. However, hypoxic tumor microenvironment hampers cuproptosis sensitivity suppresses body's antitumor response. Herein, we have successfully immobilized functionalized catalase (CAT) with long single-stranded DNA containing polyvalent CpG sequences through rolling circle amplification (RCA) techniques, obtaining an enzyme-cored spherical nucleic acid...
Aging is a degenerative process that leads to tissue dysfunction and death. Embryonic stem cells (ESCs) have great therapeutic potential for age-related diseases due their capacity self-renewal plasticity. However, the use of ESCs in clinical treatment limited by immune rejection, tumourigenicity ethical issues. ESC-derived extracellular vesicles (EVs) may provide effects are comparable those while avoiding unwanted effects. Here, we fully evaluate role ESC-EVs rejuvenation vitro vivo. Using...
Although open-central canopy (OCC) is popular in apple (Malus × domestica) orchards Loess Plateau of China, its relevant photosynthetic mechanisms have not been elucidated. In this study, changes photosynthetically active radiation (PAR), gas exchange, chlorophyll fluorescence quenching and fruit quality trees were measured OCC compared with those the conventional condensed round large (RLC). Results showed that light intercepted at different orientations was 44% higher by than RLC. The...
Cancer remains a major cause of death and severe threat to improve life span around the world. Although cancer treatments have made great progress, therapeutic outcomes malignant tumors are limited due drug resistance, side effect, and/or immunosuppressive tumor microenvironment. Traditional Chinese medicines (TCM) been approved be efficient against cancer. Compound kushen injection (CKI) is typical TCM formula, with matrine, sophocarpine, oxymatrine, oxysophocarpine as top four bioactive...
Many epidemiological studies have explored the relationship between single-nucleotide polymorphism and hepatocellular carcinoma (HCC). However, results remain controversial. We performed a large-scale meta-analysis to draw more precise estimation of aforementioned association.Studies on association microRNA (MIR) polymorphisms HCC risk that had been published up Sep 30, 2021 were identified by searching PubMed, Cochrane Library, Google Scholar, Web Science, Chinese Biomedical Literature...