Joshua Buule

ORCID: 0000-0002-1561-4908
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About
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Research Areas
  • Bacillus and Francisella bacterial research
  • Zoonotic diseases and public health
  • Poxvirus research and outbreaks
  • Yersinia bacterium, plague, ectoparasites research
  • HIV/AIDS Research and Interventions
  • SARS-CoV-2 detection and testing
  • Sex work and related issues
  • COVID-19 epidemiological studies
  • SARS-CoV-2 and COVID-19 Research
  • Liver Disease and Transplantation
  • Liver Diseases and Immunity
  • COVID-19 Clinical Research Studies
  • Microbial infections and disease research
  • Adolescent Sexual and Reproductive Health
  • Hepatitis Viruses Studies and Epidemiology
  • Long-Term Effects of COVID-19
  • Biosensors and Analytical Detection
  • Viral gastroenteritis research and epidemiology

Uganda Virus Research Institute
2020-2025

Ministry of Health
2020

Centers for Disease Control and Prevention
2020

Between April and November 2023, 27 unexplained human deaths that presented with swelling of the arms, skin sores black centers, difficulty in breathing, obstructed swallowing, headaches, other body aches were reported Kyotera District, Uganda by Public Health Emergency Operations Center. Subsequently, death cattle on farms consumption carcass meat some residents also reported. Field response teams collected clinical/epidemiological data autopsy samples to determine cause deaths. Metagenomic...

10.4269/ajtmh.24-0489 article EN cc-by American Journal of Tropical Medicine and Hygiene 2025-01-07

Abstract On April 20, 2018, the Kween District Health Office in District, Uganda reported 7 suspected cases of human anthrax. A team from Ministry and partners investigated identified 49 cases, 3 confirmed 46 suspected; no deaths were reported. Multiple exposures handling carcass a cow that had died suddenly significantly associated with cutaneous anthrax, whereas eating meat was gastrointestinal Eating undercooked but boiling for >60 minutes protective. We recommended providing postexposure...

10.3201/eid2612.191373 article EN cc-by Emerging infectious diseases 2020-11-11

Introduction Gastrointestinal anthrax is a rare but serious disease. In August 2017, Isingiro District, Uganda reported cluster of >40 persons with acute-onset gastroenteritis. Symptoms included bloody diarrhoea. We investigated to identify the etiology and exposures, inform control measures. Methods defined suspected case as diarrhoea or vomiting during 15–31 2017 in resident (aged≥2 years) Kabingo sub-county, District; confirmed was clinical sample positive for Bacillus anthracis by...

10.1371/journal.pntd.0008026 article EN public-domain PLoS neglected tropical diseases 2020-02-27

Anthrax is a zoonotic disease that can be transmitted to humans from infected animals. During May-June 2017, three persons with probable cutaneous anthrax were reported in Arua District, Uganda; one died. All had recently handled carcasses of livestock died suddenly and skin lesion deceased person tested positive by PCR for Bacillus anthracis. July, bull the same community blood sample The aim this investigation was establish scope problem, identify exposures associated illness, recommend...

10.1371/journal.pntd.0009645 article EN public-domain PLoS neglected tropical diseases 2021-08-23

IntroductionSerological testing is needed to better understand the epidemiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus. Rapid diagnostic tests (RDTs) have been developed detect specific antibodies, IgM and IgG, The performance 25 these RDTs was evaluated.MethodsA serological reference panel 50 positive 100 negative plasma specimens from SARS-CoV-2 PCR antibody patients pre-pandemic SARS-CoV-2-negative collected in 2016. Test evaluated against this...

10.1016/j.ijid.2021.09.020 article EN cc-by International Journal of Infectious Diseases 2021-09-15

Anthrax is a zoonotic infection caused by the bacteria Bacillus anthracis. Humans acquire cutaneous through contact with infected animals or animal products. On May 6, 2018, three cows suddenly died on farm in Kiruhura District. Shortly afterwards, sub-county chief District received reports of humans suspected anthrax same district. The patients had reportedly participated butchery and consumption meat from dead cows. We investigated to determine magnitude outbreak, identify exposures...

10.1186/s41182-022-00445-0 article EN cc-by Tropical Medicine and Health 2022-08-06

Abstract Background Anthrax is a vaccine-preventable disease that can be transmitted to humans from infected animals. During May–June 2017, three persons with suspected cutaneous anthrax were reported in Arua District, Uganda; one died. All had recently handled carcasses of livestock died suddenly. July, bull the same community A skin lesion deceased person and blood sample tested positive by PCR for Bacillus anthracis. The aim this investigation was establish scope problem, identify...

10.21203/rs.2.22358/v1 preprint EN cc-by Research Square (Research Square) 2020-01-31

Abstract Reporting of condom-use can limit researchers’ understanding high-risk sexual behaviours. We compared self-reported with the Yc-DNA biomarker data and investigated potential factors influencing participation in, reporting of, Self-reported were collected using Audio Computer Assisted Self Interviews (ACASI) samples for self-administered health worker-collected vaginal swabs from 644 women (aged 15–24 years) who not living HIV. results interview McNemar-Bowker Analysis Cohen’s Kappa....

10.1007/s10461-023-04177-y article EN cc-by AIDS and Behavior 2023-09-26

Abstract Background : Anthrax is a zoonotic vaccine-preventable disease that can be transmitted to humans from infected animals. During May–June 2017, three persons with probable cutaneous anthrax were reported in Arua District, Uganda; one died. All had recently handled carcasses of livestock died suddenly. July, bull the same community A skin lesion deceased person and blood sample tested positive by PCR for Bacillus anthracis. The aim this investigation was establish scope problem,...

10.21203/rs.2.22358/v2 preprint EN cc-by Research Square (Research Square) 2020-06-23
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