A5084143590- Circular RNAs in diseases
- MicroRNA in disease regulation
- Smoking Behavior and Cessation
- Cytokine Signaling Pathways and Interactions
- Obesity, Physical Activity, Diet
- Growth Hormone and Insulin-like Growth Factors
- Cancer-related molecular mechanisms research
- Cancer Research and Treatments
- Cancer Cells and Metastasis
- Medicinal Plant Pharmacodynamics Research
- Management of metastatic bone disease
- Indoor Air Quality and Microbial Exposure
- Carcinogens and Genotoxicity Assessment
- Ovarian cancer diagnosis and treatment
- Reproductive System and Pregnancy
- Innovations in Medical Education
- Cancer Risks and Factors
- Cancer Treatment and Pharmacology
- Primary Care and Health Outcomes
- Diversity and Career in Medicine
- Consumer Attitudes and Food Labeling
- Eating Disorders and Behaviors
- Cancer survivorship and care
- Immune cells in cancer
- Estrogen and related hormone effects
Stanford University
2020-2024
Realistic Education in Action Coalition to Foster Health
2023-2024
Memorial Sloan Kettering Cancer Center
2021
Society of Teachers of Family Medicine
2021
University of Oxford
2018
University of California, Los Angeles
2015
Pacific Union College
2012-2014
Chang Gung University of Science and Technology
2014
Chang Gung Memorial Hospital
2014
Kaohsiung Chang Gung Memorial Hospital
2013
Abstract Malignant ascites is a common complication in the late stages of epithelial ovarian cancer (EOC) that greatly diminishes quality life patients. known consequence vascular dysfunction, but current approved treatments are not effective preventing fluid accumulation. In this study, we investigated an alternative strategy targeting macrophage functions to reverse pathology malignant using from human patients and immunocompetent murine model (ID8) EOC mirrors disease by developing...
Abstract Purpose: The proinflammatory cytokine interleukin-32 (IL-32) is a novel tumor marker highly expressed in various human carcinomas, including gastric cancer. However, its effects on prognosis of patients with cancer and metastasis are virtually unknown at present. main aim this study was to explore the clinical significance IL-32 further elucidate molecular mechanisms underlying IL-32–mediated migration invasion. Experimental Design: Gastric cells ectopic expression or silencing were...
E-cigarettes, the most popular tobacco product among adolescents, vary widely in design and nicotine composition; thus, different devices may have addictive potential. However, few studies examine levels of dependence across adolescent young adult (AYA) e-cigarette users. To assess extent US AYA (ages 13-24) by device type, we conducted a large, national, cross-sectional survey (n = 4351) used Hooked on Nicotine Checklist (HONC) to those who had disposable, pod-based, and/or mods/other past...
Thyroid hormone (T(3)) signaling through the thyroid receptor (TRα1) regulates hepatoma cell growth and pathophysiology, but underlying mechanisms are unclear at present. Here, we have shown that oncomir microRNA-21 (miR-21) is activated by T(3) a native response element in primary miR-21 promoter. Overexpression of promoted migration invasion, similar to observed with stimulation cells. In addition, anti-miR-21-induced suppression was rescued T(3). The Rac-controlled regulator invasion...
Nonnicotine e-cigarettes contain chemicals, flavorants, and solvents that have known health harms and/or not been proven safe for inhalation.To evaluate nonnicotine e-cigarette use patterns, including common flavors, brands, ingredients.This cross-sectional study included a convenience sample of US residents aged 13 to 40 years who completed an online survey in November December 2021. Quota sampling was used equal proportion participants 17 years, 18 20 21 balanced sex, race, ethnicity per...
Previous in vitro and case-control studies have found an association between the insulin-like growth factor (IGF)-axis bladder cancer risk. Circulating concentrations of IGF-I also been to be associated with increased risk several types; however, relationship pre-diagnostic circulating has never studied prospectively. We investigated plasma overall urothelial cell carcinoma (UCC) a study nested within European Prospective Investigation into Cancer Nutrition (EPIC) cohort. A total 843 men...
<p>PDF File - 47K, Effect of T3 on primary miR-21 in HepG2-TR�1 cells.</p>
<p>PDF File - 97K, Homo sapiens microRNA pri-miR-21, complete sequence.</p>
<p>PDF - 38K, Sequence of primary miR-21 promoter region (-3000/+1).</p>
<p>PDF - 144K, Schematic effects of miR-21 regulated by T3 on cell migration and invasion.</p>
<p>PDF File - 116K, Full-length 3'UTR sequence of TIAM1 and MSH2.</p>
<p>PDF - 179K, MSH2 is a miR-21 target downregulated by T3.</p>
<p>PDF - 655K, The effects of T3, miR-21 and TIAM1 in SK-Hep1 cells.</p>
<p>PDF - 144K, Schematic effects of miR-21 regulated by T3 on cell migration and invasion.</p>