A5029133680- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- Reproductive tract infections research
- Syphilis Diagnosis and Treatment
- HIV Research and Treatment
- Sex work and related issues
- HIV/AIDS drug development and treatment
- Nanoparticle-Based Drug Delivery
- Adolescent Sexual and Reproductive Health
- Herpesvirus Infections and Treatments
- COVID-19 epidemiological studies
- Computational Drug Discovery Methods
- COVID-19 Digital Contact Tracing
- LGBTQ Health, Identity, and Policy
- Female Genital Mutilation/Cutting Issues
- Geriatric Care and Nursing Homes
- Ethics in Clinical Research
- Homelessness and Social Issues
- Genital Health and Disease
- Urinary and Genital Oncology Studies
- Urinary Tract Infections Management
- Urologic and reproductive health conditions
- Poxvirus research and outbreaks
- Reproductive Health and Contraception
- Cell Adhesion Molecules Research
University of California, San Francisco
2015-2025
San Francisco Department of Public Health
2016-2025
University of California System
2024
University of Washington
2024
San Francisco General Hospital
2024
Emory University
2024
Christ University
2024
Jacobs (United States)
2023
Center for Surveillance, Epidemiology, and Laboratory Services
2022
AID Atlanta
2022
<h3>Importance</h3> Several randomized clinical trials have demonstrated the efficacy of preexposure prophylaxis (PrEP) in preventing human immunodeficiency virus (HIV) acquisition. Little is known about adherence to regimen, sexual practices, and overall effectiveness when PrEP implemented clinics that treat sexually transmitted infections (STIs) community-based serving men who sex with (MSM). <h3>Objective</h3> To assess adherence, behaviors, incidence STIs HIV infection a cohort MSM...
Albert Liu and colleagues report early experiences with uptake delivery of pre-exposure prophylaxis(PrEP)for HIV prevention in three different settings San Francisco. PrEP can be an important component a comprehensive program complement efforts to increase testing, linkage care, initiation antiretroviral therapy. Please see later the article for Editors' Summary
Interventions to reduce sexually transmitted infections (STIs) among men who have sex with (MSM) are needed. Download a PDF of the Research Summary. We conducted an open-label, randomized study involving MSM and transgender women were taking preexposure prophylaxis (PrEP) against human immunodeficiency virus (HIV) infection (PrEP cohort) or living HIV (persons [PLWH] had Neisseria gonorrhoeae (gonorrhea), Chlamydia trachomatis (chlamydia), syphilis in past year. Participants randomly...
In the United States, approximately 1.4 million persons access emergency shelter or transitional housing each year (1). These settings can pose risks for communicable disease spread. late March and early April 2020, public health teams responded to clusters (two more cases in preceding 2 weeks) of coronavirus 2019 (COVID-19) residents staff members from five homeless shelters Boston, Massachusetts (one shelter); San Francisco, California (one); Seattle, Washington (three). The investigations...
Background It is unknown if extremely early initiation of antiretroviral therapy (ART) may lead to long-term ART-free HIV remission or cure. As a result, we studied 2 individuals recruited from pre-exposure prophylaxis (PrEP) program who started prophylactic ART an estimated 10 days (Participant A; 54-year-old male) and 12 B; 31-year-old after infection with peak plasma RNA 220 copies/mL 3,343 copies/mL, respectively. Extensive testing blood tissue for persistence was performed, PrEP...
High prevalences of HIV and other sexually transmitted infections (STIs) have been reported in the current global monkeypox outbreak, which has affected primarily gay, bisexual, men who sex with (MSM) (1-5). In previous outbreaks Nigeria, concurrent infection was associated poor clinical outcomes (6,7). Monkeypox, HIV, STI surveillance data from eight U.S. jurisdictions* were matched analyzed to examine diagnoses among persons assess differences features according status. Among 1,969 during...
Background: Preexposure prophylaxis (PrEP) is the first biomedical intervention with proven efficacy to reduce HIV acquisition in men who have sex (MSM) and transgender women. Little known about levels of interest characteristics individuals elect take PrEP real-world clinical settings. Methods: The US Demonstration Project a prospective open-label cohort study assessing delivery municipal sexually transmitted disease clinics San Francisco Miami community health center Washington, DC....
We report the public health response to a coronavirus disease 2019 (COVID-19) outbreak in San Francisco shelter where 67% of residents and 17% staff tested positive for severe acute respiratory syndrome 2 (SARS-CoV-2). describe limited utility case investigation, person-based contact tracing symptom screening, benefits mass testing response.
Doxycycline postexposure prophylaxis (doxy-PEP) reduces sexually transmitted infections (STIs) in men who have sex with (MSM) and transgender women (TGW). In a clinical trial of doxy-PEP, we sought to assess acceptability, impact, meaning doxy-PEP use among MSM/TGW. We conducted semistructured, in-depth 1:1 interviews MSM TGW enrolled the intervention arm Doxy-PEP study. queried motivations for use, attitudes, beliefs, adherence, effect on sexual behaviors, partner, community, structural...
We examined rates of and risk factors for repeat syphilis infection among men who have sex with (MSM) in California.We analyzed 2002 to 2006 California surveillance system data.During the study period, a mean 5.9% (range: 4.9%-7.1% per year) MSM had primary or secondary (PS) within 2 years an initial infection. There was no significant increase annual proportion (P = .42). In multivariable model, associated were HIV (odds ratio [OR] 1.65; 95% confidence interval [CI] 1.14, 2.37), Black race...
Pre-exposure prophylaxis (PrEP) for prevention of HIV infection has demonstrated efficacy in randomized controlled trials and demonstration projects. For PrEP implementation to result significant reductions incidence men who have sex with the United States, sufficient access care continued engagement outside projects is required.We report results a follow-up survey 173 former participants from Miami San Francisco sites US Demo Project, administered 4-6 months after study completion.Survey...
After the initial approval of use tenofovir disoproxil fumarate-emtricitabine (TDF/FTC) by US Food and Drug Administration in 2012 for anti-HIV pre-exposure prophylaxis (PrEP), uptake was initially limited, but more recent community surveys expert opinion suggest wider acceptance some key populations.Demonstration projects are underway to determine best practices United States identify at-risk individuals primary care sexually transmitted disease clinics who could benefit from PrEP. Studies...
The US preexposure prophylaxis (PrEP) Demonstration Project (U.S. Demo) evaluated MSM on PrEP postmarketing and found low seroconversion rates. objective of this study is to examine hair levels as an adherence measure PrEP.
<h3>Importance</h3> Although acute HIV infection contributes disproportionately to onward transmission, testing has not routinely included screening for infection. <h3>Objective</h3> To evaluate the performance of an antigen/antibody (Ag/Ab) combination assay detect compared with pooled RNA testing. <h3>Design, Setting, and Participants</h3> Multisite, prospective, within-individual comparison study conducted between September 2011 October 2013 in 7 sexually transmitted clinics 5...