A5004131213- Reproductive tract infections research
- Syphilis Diagnosis and Treatment
- Adolescent Sexual and Reproductive Health
- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- Reproductive Health and Contraception
- Herpesvirus Infections and Treatments
- Cervical Cancer and HPV Research
- Female Genital Mutilation/Cutting Issues
- Bacillus and Francisella bacterial research
- Urinary Tract Infections Management
- Poxvirus research and outbreaks
- Virology and Viral Diseases
- Hepatitis B Virus Studies
- Infective Endocarditis Diagnosis and Management
- Prenatal Screening and Diagnostics
- Cytomegalovirus and herpesvirus research
- Ethics in Clinical Research
- Bacterial Infections and Vaccines
- Vaccine Coverage and Hesitancy
- Sexuality, Behavior, and Technology
- Sex work and related issues
- Genital Health and Disease
- Colorectal and Anal Carcinomas
- Blood groups and transfusion
Wake Forest University
2009-2024
CDC Foundation
2024
Centers for Disease Control and Prevention
2018-2024
National Center for HIV/AIDS Viral Hepatitis STD and TB Prevention
2018-2024
The University of Texas Health Science Center at Houston
2024
Foundation Center
2024
Emory University
2024
The Centers
2024
Community Link
2024
University Medical Center of the Johannes Gutenberg University Mainz
2023
These guidelines for the treatment of persons who have or are at risk sexually transmitted infections (STIs) were updated by CDC after consultation with professionals knowledgeable in field STIs met Atlanta, Georgia, June 11-14, 2019. The information this report updates 2015 guidelines. discuss 1) recommendations Neisseria gonorrhoeae, Chlamydia trachomatis, and Trichomonas vaginalis; 2) addition metronidazole to recommended regimen pelvic inflammatory disease; 3) alternative options...
Sexually transmitted infections (STIs) caused by the bacteria Neisseria gonorrhoeae (gonococcal infections) have increased 63% since 2014 and are a cause of sequelae including pelvic inflammatory disease, ectopic pregnancy, infertility can facilitate transmission human immunodeficiency virus (HIV) (1,2). Effective treatment prevent complications transmission, but N. gonorrhoeae's ability to acquire antimicrobial resistance influences recommendations complicates control (3). In 2010, CDC...
On May 17, 2022, the Massachusetts Department of Public Health (MDPH) Laboratory Response Network (LRN) laboratory confirmed presence orthopoxvirus DNA via real-time polymerase chain reaction (PCR) from lesion swabs obtained a resident. Orthopoxviruses include Monkeypox virus, causative agent monkeypox. Subsequent PCR testing at CDC on 18 that patient was infected with West African clade virus. Since then, cases* have been reported by nine states. In addition, 28 countries and territories,†...
High prevalences of HIV and other sexually transmitted infections (STIs) have been reported in the current global monkeypox outbreak, which has affected primarily gay, bisexual, men who sex with (MSM) (1-5). In previous outbreaks Nigeria, concurrent infection was associated poor clinical outcomes (6,7). Monkeypox, HIV, STI surveillance data from eight U.S. jurisdictions* were matched analyzed to examine diagnoses among persons assess differences features according status. Among 1,969 during...
No vaccines and few chemoprophylaxis options exist for the prevention of bacterial sexually transmitted infections (STIs) (specifically syphilis, chlamydia, gonorrhea). These have increased in United States disproportionately affect gay, bisexual, other men who sex with (MSM) transgender women (TGW). In three large randomized controlled trials, 200 mg doxycycline taken within 72 hours after has been shown to reduce syphilis chlamydia by >70% gonococcal approximately 50%. This report outlines...
Congenital syphilis cases in the United States increased 755% during 2012-2021. Syphilis pregnancy can lead to stillbirth, miscarriage, infant death, and maternal morbidity; these outcomes be prevented through appropriate screening treatment.A cascading framework was used identify classify missed opportunities prevent congenital among reported CDC 2022 National Notifiable Diseases Surveillance System. Data on testing treatment clinical manifestations present newborn were syphilis.In 2022, a...
ABSTRACT It is uncertain which methods for the diagnosis of rectal gonococcal and chlamydial infection are optimal. This study evaluated performance culture nucleic acid amplification tests (NAATs) diagnosis. From July 2003 until February 2007, 441 test sets were collected from individuals attending a sexually transmitted disease clinic three HIV clinics who gave history anal intercourse or women at high risk Neisseria gonorrhoeae Chlamydia trachomatis infections. Rectal swab specimens...
The optimal methods for the diagnosis of pharyngeal Neisseria gonorrhoeae infection are uncertain. objective this study was to define performance culture and nucleic acid amplification tests (NAATs) N. gonorrhoeae. In cross-sectional study, males females >15 years old who acknowledged performing fellatio or cunnilingus (in previous 2 months) were recruited from three clinics (two human immunodeficiency virus one sexually transmitted diseases clinic) located in Birmingham, AL. test...
Congenital syphilis is an infection with Treponema pallidum in infant or fetus, acquired during pregnancy from a mother untreated inadequately treated syphilis. can cause miscarriage, stillbirth, early death, and infected infants experience lifelong physical neurologic problems. Although timely identification treatment of maternal prevent congenital (1,2), the number reported cases United States increased 261% 2013-2018, 362 to 1,306. Among 2018, total 94 resulted stillbirths deaths (3)....
We tested an intervention designed to increase human immunodeficiency virus (HIV) testing among men who have sex with and transgender persons within existing commonly used social media. At follow-up, communities had significantly higher past 12-month HIV than the comparison communities. Findings suggest that promoting via media can testing.
A multicountry outbreak of mpox (formerly monkeypox) in 2022 has affected gay, bisexual, and other men who have sex with disproportionately, highlighting the need to understand role sexual contact transmission.• While virus (mpoxv) is not a novel pathogen been circulating subsaharan Africa for many years, transmission well described.• Epidemiological, clinical, virological data indicate that mpoxv through contact, both penetrative nonpenetrative, more effective than casual skin-to-skin...
Trichomonas vaginalis (TV) infection is the most prevalent curable sexually transmitted in United States and worldwide. Most TV infections are asymptomatic, accurate diagnosis of this has been limited by lack sufficiently sensitive specific diagnostic tests, particularly for men. To provide updates 2010 Centers Disease Control Prevention's Sexually Transmitted Diseases Treatment Guidelines, a PubMed search was conducted all literature published from 9 January 2004 through 24 September 2008....
The Internet has emerged as an important tool for the delivery of health promotion and disease prevention interventions. Our community-based participatory research (CBPR) partnership developed piloted CyBER/testing, a culturally congruent intervention designed to promote HIV testing among men who have sex with (MSM) within existing chat rooms. Using quasi-experimental, single-group study design, cross-sectional data were collected from room participants, known "chatters," at pretest (n =...
Antimicrobial resistance in Mycoplasma genitalium (MG), a cause of urethritis, is growing concern. Yet little known about the geographic distribution MG United States or its associated clinical outcomes. We evaluated frequency among men with mutations, and posttreatment symptom persistence.We enrolled presenting urethritis symptoms to 6 US sexually transmitted disease (STD) clinics during June 2017-July 2018; were eligible for follow-up contact and, if they had persistent MG, chart review....
Renewed interest in developing vaccines against Neisseria gonorrhoeae has been sparked by the increasing threat of gonococcal antimicrobial resistance (AMR) and growing optimism that are biologically feasible. Evidence suggests serogroup B meningitidis might provide some cross-protection N. gonorrhoeae, new vaccine candidates based on several approaches currently preclinical development. To further stimulate investment accelerate development vaccines, greater understanding is needed...
COVID-19 has brought unprecedented challenges to clinical and public health laboratories. While U.S. laboratories have continued striving provide quality test results during the pandemic, uncertainty lack of supplies became a significant hurdle, hindering day-to-day laboratory operations ability increase testing capacity for both SARS-CoV-2 non-COVID-19 testing. In addition, long-standing workforce shortages apparent, rapidly The American Society Microbiology, College Pathologists, National...
Trichomoniasis is the most prevalent curable sexually transmitted disease (STD). It has been associated with preterm birth and acquisition transmission of HIV. Recently, nucleic acid amplification tests (NAAT) have FDA cleared in United States for detection Trichomonas vaginalis specimens from both women men. This study reports results a multicenter recently conducted using Xpert TV (T. vaginalis) assay to test men women. On-demand were available as little 40 min positive specimens. A total...