- Innovative Microfluidic and Catalytic Techniques Innovation
- Microfluidic and Bio-sensing Technologies
- Electrowetting and Microfluidic Technologies
- Microfluidic and Capillary Electrophoresis Applications
- 3D Printing in Biomedical Research
- Luminescence and Fluorescent Materials
- Analytical Chemistry and Sensors
- Molecular Sensors and Ion Detection
- Advanced Sensor and Energy Harvesting Materials
- Photochromic and Fluorescence Chemistry
- Effects and risks of endocrine disrupting chemicals
- Sepsis Diagnosis and Treatment
- Odor and Emission Control Technologies
- Fiber-reinforced polymer composites
- Toxic Organic Pollutants Impact
- Single-cell and spatial transcriptomics
- Orthopaedic implants and arthroplasty
- Surface and Thin Film Phenomena
- Algal biology and biofuel production
- Meat and Animal Product Quality
- Reproductive Biology and Fertility
- Photochemistry and Electron Transfer Studies
- Neuroscience and Neural Engineering
- Textile materials and evaluations
- Electrochemical sensors and biosensors
Seoul National University of Science and Technology
2024
Sungkyunkwan University
2016-2024
Konkuk University
2024
Chungbuk National University
2022
Massachusetts Institute of Technology
2018-2021
University of California, Irvine
2017-2019
Irvine Valley College
2017-2018
University of California System
2017
Korea Advanced Institute of Science and Technology
2007-2016
Samsung Medical Center
2016
Even though persistent organic pollutants (POPs) are well-known neurotoxicants, there is no previous study, even cross-sectional, on the association between background exposure to POPs and clinically significant developmental disorders, such as learning disability (LD) or attention deficit disorder (ADD), among children from a general population.Cross-sectional study.Study subjects were 278 aged 12-15 years included in National Health Nutrition Examination Survey 1999-2000. The seven most...
Although shortened telomeres have been found in many cancers, elongated telomere length has observed as an early response after low-dose treatment with various chemical carcinogens vitro and animal experiments, suggesting exposure to carcinogenic chemicals may function a tumour promoter at the very stage of carcinogenesis humans. This cross-sectional study was performed examine whether persistent organic pollutants (POPs), lipophilic xenobiotics that mainly bioaccumulate adipose tissue, is...
We present a method to discriminate normal oocytes in an optoelectrofluidic platform based on the optically induced positive dielectrophoresis (DEP) for vitro fertilization. By combining gravity with pulling-up DEP force that is by dynamic image projected from liquid crystal display, discrimination performance could be enhanced due reduction friction acting are relatively large and heavy cells being affected field. The voltage condition of 10 V bias at 1 MHz was applied moving oocytes....
Rapid and label-free single-leukemia-cell identification through fluorescence lifetime imaging microscopy (FLIM) in the high-density microfluidic trapping array.
We created an integrated microfluidic cell separation system that incorporates hydrophoresis and dielectrophoresis modules to facilitate high-throughput continuous separation. The module consists of a serpentine channel with ridges trenches generate diverging fluid flow focuses cells into two streams along the edges. is composed chevron-shaped electrode array. Separation in driven by inherent electrophysiological properties does not require cell-type-specific labels. chevron shape array...
Microalgae, a group of microorganisms that grow using sunlight as the sole energy source and carbon dioxide an only source, have been considered feedstock choice for production biofuels such biodiesel. To explore economic feasibility application, however, many technical hurdles must first be overcome; selection and/or screening competent species are some most important yet challenging tasks. greatly accelerate this rather slow laborious step, we developed droplet-based microfluidic system...
Abstract While lipoplex (cationic lipid‐nucleic acid complex)‐mediated intracellular delivery is widely adopted in mammalian cell transfection, its transfection efficiency for suspension cells, e.g., lymphatic and hematopoietic reported at only ≈5% or even lower. Here, efficient consistent lipoplex‐mediated demonstrated hard‐to‐transfect cells via a single‐cell, droplet‐microfluidics approach. In these microdroplets, monodisperse lipoplexes effective gene are generated chaotic mixing induced...
Background: Bipolar hemiarthroplasty for unstable intertrochanteric fractures in elderly patients is a viable option that can prevent the complications of an open reduction, such as nonunion and metal failure.This study evaluated clinicoradiological results cementless bipolar patients.Methods: Forty hips were followed more than 2 years after using Porocoat ® AML Hip System.The mean age was 78.8 follow-up period 40.5 months.The Harris hip score postoperative pain analyzed clinically.The...
mRNA probing from single cells within microfluidic arrays, combining the non-destructive and precise-control of a single-cell probe with sealed systems' multifunctional capability.
We studied 11 patients with checkrein deformities of the hallux who underwent surgical treatment. Six had lengthening flexor hallucis longus tendon by Z-plasty in midfoot, and five release adhesions at musculotendinous junction fracture site. All six midfoot showed complete correction deformity without recurrence. Of site, two partial one
Water evaporation-driven energy harvesting is an emerging mechanism for contributing to green production with low cost. Herein, we developed polyacrylonitrile (PAN) nanofiber-based electricity generators (PEEGs) confirm the feasibility of utilizing electrospun PAN nanofiber mats in system. However, require a support substrate enhance its durability and stability when it applied generator, which could have additional effects on generation performance. Accordingly, various substrates,...
Over the last decade, incidence of ultraviolet B (UVB)-related skin problems has increased. Oxidative stress caused by UVB induces secretion melanocyte growth and activating factors from keratinocytes, which results in formation cutaneous hyperpigmentation. Therefore, increasing antioxidant abilities cells is thought to be a beneficial strategy for development sunscreen agents. Superoxide dismutase 1 (SOD1) an enzyme that known exhibit properties. The purpose this study was investigate...
We report a fully automated, sample-to-answer, and label-free leukocyte activation analysis platform for monitoring immune responses in sepsis, by integrating the multidimensional double spiral (MDDS) isodielectric separation (IDS) subplatforms. The integrated can provide rapid automated identification of clinically diagnosed sepsis patients from only 50 μL peripheral blood volume within 25 min. Many critical innovations were implemented direct interconnection between two subplatforms, such...
Sepsis is a critical illness characterized by dysregulated inflammatory responses lacking counter-regulation. Specialized proresolving mediators are agonists for antiinflammation and promoting resolution, they protective in preclinical sepsis models. Here, human sepsis, we mapped resolution circuits the specialized resolvin D1 D2 peripheral blood neutrophils monocytes, their regulation of leukocyte activation function ex vivo, relationships to measures clinical severity. Neutrophils...