A5019599361- Nuclear Physics and Applications
- Radiation Detection and Scintillator Technologies
- Radiation Therapy and Dosimetry
- X-ray Spectroscopy and Fluorescence Analysis
- Particle Detector Development and Performance
- Radiopharmaceutical Chemistry and Applications
- Ion-surface interactions and analysis
- Particle accelerators and beam dynamics
- Atomic and Subatomic Physics Research
- High-Energy Particle Collisions Research
- Nuclear reactor physics and engineering
- Particle physics theoretical and experimental studies
- Nuclear physics research studies
- Advanced Radiotherapy Techniques
- Electron and X-Ray Spectroscopy Techniques
- Radiation Effects in Electronics
- Atomic and Molecular Physics
- Boron Compounds in Chemistry
- Nuclear Materials and Properties
- Diamond and Carbon-based Materials Research
- Particle Accelerators and Free-Electron Lasers
- Superconducting Materials and Applications
- Chemical Reactions and Isotopes
- Cultural Heritage Materials Analysis
- Quantum Chromodynamics and Particle Interactions
IMT Atlantique
2016-2024
Laboratoire de Physique Subatomique et des Technologies Associées
2015-2024
Centre National de la Recherche Scientifique
2011-2024
Nantes Université
2012-2024
Institut National de Physique Nucléaire et de Physique des Particules
1995-2024
Institut Génétique Nantes Atlantique
2020
École Nationale Supérieure des Mines de Paris
1998-2017
Champalimaud Foundation
2016
Centre de Gestion Scientifique
1996-2000
Lantiq (Germany)
1999
Experimental data obtained with the 4π multidetector system INDRA are used to study light charged particle (LCP, Z<~2) and intermediate mass fragment (IMF, Z>~3) production in peripheral semicentral collisions of Xe Sn at 50 MeV/nucleon. It is found that a sizable fraction detected LCP’s IMF’s originates from midvelocity region. These fragments can be seen come either prompt (preequilibrium) mechanism or slower but dynamically influenced emission process. The relative magnitude isotropic...
During ultra-high dose rate (UHDR) external radiation therapy, healthy tissues appear to be spared while tumor control remains the same compared conventional rate. However, understanding of radiochemical and biological mechanisms involved are still discussed. This study shows how hydrogen peroxide (H2O2) production, one reactive oxygen species (ROS), could controlled by early heterogenous radiolysis processes in water during UHDR proton-beam irradiations. Pure was irradiated plateau region...
The ARRONAX cyclotron facility offers the possibility to deliver proton beams from low ultra-high dose rates (UHDR). As a good control of dosimetry is prerequisite UHDR experimentations, we evaluated in different conditions usability and rate dependency several radiochromic films commonly used for radiotherapy.We compared three types films: GAFchromic™ EBT3 EBT-XD (Ashland Inc., Wayne, NJ, USA), OrthoChromic OC-1 (OrthoChrome Hillsborough, after irradiations at various mean (0.25, 40, 1500,...
Among the large number of radionuclides medical interest, Sc-44 is promising for PET imaging. Either ground-state Sc-44g or metastable-state Sc-44m can be used such applications, depending on molecule as vector. This study compares production rates both states, when protons deuterons are projectiles an enriched Calcium-44 target. work presents first set data deuteron route. The results compared with TALYS code. Thick-Target Yields and calculated those proton route three different scenarios:...
Mo-99 TTY obtain in this work is up to 25%
Radiobiological effectiveness of radiation in cancer treatment can be studied at different scales (molecular till organ scale) and time post irradiation. The production free radicals reactive oxygen species during water radiolysis is particularly relevant to understand the fundamental mechanisms playing a role observed biological outcomes. development validation Monte Carlo tools integrating simulation physical, physico-chemical chemical stages after very important maintain with experiments.
K-shell X-ray production cross-sections measurement campaigns were carried out at the ARRONAX cyclotron with titanium, chromium, copper, molybdenum, silver and gold targets for different energies from 15 to 68 MeV. These measurements, using three detectors (SDD, CdTe HPGe), complete database 66 new values. Our measurements agree previously published data are consistent all detectors, confirming absence of experimental bias. The universal ionisation cross-section representation allows an...
The cyclotron ARRONAX can deliver different types of particles (protons, deuterons, alpha-particles) in an energy range up to 68 MeV. One its six experimental halls is dedicated studying the interactions radiation with matter including living matter. A horizontal beamline for cell irradiation has been setup and characterized. radiobiological characterization was done terms V79 cells survival after MeV protons. results demonstrate that studies be successfully performed confirming high...