A5009515814- Health and Medical Studies
- COVID-19 and Mental Health
- COVID-19 epidemiological studies
- Legionella and Acanthamoeba research
- Infection Control and Ventilation
- Respiratory viral infections research
- Pediatric health and respiratory diseases
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Vibrio bacteria research studies
- Pneumocystis jirovecii pneumonia detection and treatment
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Long-Term Effects of COVID-19
- Bacillus and Francisella bacterial research
- Gut microbiota and health
- Pleural and Pulmonary Diseases
- Immune Cell Function and Interaction
- COVID-19 and healthcare impacts
- COVID-19 Impact on Reproduction
- SARS-CoV-2 detection and testing
- Bacterial biofilms and quorum sensing
- Viral Infections and Outbreaks Research
- Neonatal Health and Biochemistry
- Travel-related health issues
- Pneumothorax, Barotrauma, Emphysema
Robert Koch Institute
2018-2024
Mitigation of the coronavirus disease (COVID-19) pandemic in Germany included school closures early March 2020. After reopening April, preventive measures were taken schools. We analysed national surveillance system data on COVID-19 outbreaks during different time periods. reopening, smaller (average: 2.2/week) occurred despite low incidence general population. School might have a detrimental effect children and should be applied only cautiously combination with other measures.
We investigated three SARS-CoV-2 variant B.1.1.7 childcare centre and related household outbreaks. Despite group cohorting, cases occurred in almost all groups, i.e. also among persons without close contact. Children's secondary attack rates (SAR) were similar to adults (childcare centres: 23% vs 30%; p = 0.15; households: 32% 39%; 0.27); child- adult-induced outbreaks led SAR. With the advent of B.1.1.7, susceptibility infectiousness children seem converge. Public health measures should be...
Abstract Background During the SARS-CoV-2 pandemic, German early childhood education and care (ECEC) centres organised children’s attendance in different ways, they reduced opening hours, provided emergency support for a few children, or closed completely. Further, protection hygiene measures like fixed children-staff groups, ventilation surface disinfection were introduced ECEC centres. To inform modify public health ECEC, we investigate occurrence of infections among children staff light...
Before the COVID-19 pandemic, acute respiratory infections (ARIs) in children were mainly characterised by three pathogens: syncytial viruses (RSV), influenza and rhinoviruses. The impact of pandemic measures taken Germany (especially until end 2021) on incidence ARI adolescents aged 0 to 14 years pathogens causing them has not yet been comprehensively analysed.The evaluation is based data from population-based, virological hospital-based surveillance instruments up 2022.After onset early...
As of December 31, 2019, initial reports circulated internationally an unusual cluster pneumonia unknown cause in China. By the end January 2020, virus affected Germany with first case confirmed on 27, 2020. Intensive contact tracing and infection control measures contained two clusters country. However, dynamic wave gained momentum as March, by mid-June 2020 over 190,000 laboratory-confirmed cases had been reported to Robert Koch Institute. This article examines these part a retrospective...
Abstract Background During the five waves of SARS-CoV-2 pandemic so far, German early childhood education and care (ECEC) centres implemented various protective measures, such as wearing a face mask, fixed children-staff groups or regular ventilation. In addition, parents ECEC staff were increasingly vaccinated throughout 2021. 4th wave, variant concern (VOC) Delta-driven transmission indicators reached record values at end Those even exceeded in 5th wave beginning 2022 when Omicron...
Using participatory, virologic, and wastewater surveillance systems, we estimated when to what extent reported data of adult COVID-19 cases underestimated incidence in Germany. We also examined how case underestimation evolved over time. Our findings highlight community-based systems can complement official notification for respiratory disease dynamics.
Sources of infection most cases community-acquired Legionnaires' disease (CALD) are unknown.
Abstract Background During the SARS-CoV-2 pandemic, German early childhood education and care (ECEC) centres organised childrens attendance variably (i.e., reduced opening hours, emergency support for few children only or full close-down). Further, protection hygiene measures like fixed children/staff groups, ventilation surface disinfection were introduced among ECEC centres. To inform modify public health in ECEC, we investigate occurrence of infections staff light social determinants...
Daycare centers are of substantial sociopolitical and pedagogical relevance; at the same time, close contact children in daycare groups among each other with employees favors transmission infections. In COVID-19 pandemic, questions arose about how infection events occur centers, what role play protective hygienic measures implemented centers. From 06/2020 to 12/2021, we conducted "Corona Day Care Study," which address epidemiological topics a joint approach.
The evidence for the incubation period of Legionnaires' disease is based on data from a small number outbreaks. An 2-10 days commonly used definition and investigation cases. In German LeTriWa study, we collaborated with public health departments to identify evidence-based sources exposure among cases within 1-14 before symptom onset. For each individual, assigned weights numbered onset, giving highest weight only one possible day exposure. We then calculated an distribution where median was...
The "LeTriWa study" on community-acquired cases of Legionnaires' disease (LD) found that most likely acquired their infection at home (AHALD). However, which sources confer the is largely unknown. We therefore analyzed data set from LeTriWa study to find out if individual were associated with AHALD and specific behavioral habits may increase or lower risk for AHALD.During we had used two comparison groups: (i) controls matched age group hospital ("controls"), (ii) household members...
Zusammenfassung Hintergrund Die Symptomatik einer pädiatrischen SARS-CoV-2-Infektion ist sehr variabel. Es gibt nur wenige Studien zu nichthospitalisierten Kindern bzw. im Kita-Alter. Ziel der Arbeit soll die Häufigkeit verschiedener COVID-19-Symptome bei ein- bis 6‑jährigen beschreiben. Sie führt dazu Daten aus 2 Modulen Corona-KiTa-Studie zusammen: 1) das Modul „COALA“ – Corona: Anlassbezogene Untersuchungen in Kitas und 2) „CATS“ Corona KiTa Surveillance (Meldedaten). Material Methoden In...
Abstract Introduction Sources of infection most cases community-acquired Legionnaires’ disease (CALD) are unknown. Objective Identification sources CALD. Setting Berlin; December 2016–May 2019. Participants Adult CALD reported to district health authorities and consenting the study; age hospital matched controls. Main outcome measure Percentage with identified source infection. Methods Analysis secondary patient samples for monoclonal antibody (MAb) type (and sequence type);...
Background: During the five waves of SARS-CoV-2 pandemic so far, German early childhood education and care (ECEC) centres implemented various protective measures, such as wearing a face mask, fixed children-staff groups or regular ventilation. In addition, parents ECEC staff were increasingly vaccinated throughout 2021. 4th wave, variant concern (VOC) Delta-driven transmission indicators reached record values at end Those even exceeded in 5th wave beginning 2022 when Omicron dominated. We...
We determined whether the incidence rates of travel-associated Legionnaires' disease (TALD) in hotels Germany increased after a previous occurrence and control measures required by European Disease Surveillance Network cluster (>2 cases within 2 years) restored rate to baseline. analyzed TALD surveillance data from during 2015-2019; total 307 (163 domestic, 144 nondomestic) were reported. The ratio was 5.5 (95% CI 3.6-7.9) for second case 25 11-50) third had occurred, suggesting that...