A5036138723- Peripheral Nerve Disorders
- Nerve Injury and Rehabilitation
- Orthopedic Surgery and Rehabilitation
- Shoulder Injury and Treatment
- Neurofibromatosis and Schwannoma Cases
- Meningioma and schwannoma management
- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Shoulder and Clavicle Injuries
- Myofascial pain diagnosis and treatment
- Nerve injury and regeneration
- Tendon Structure and Treatment
- Glioma Diagnosis and Treatment
- Pain Management and Treatment
- Facial Nerve Paralysis Treatment and Research
- Intracranial Aneurysms: Treatment and Complications
- Medical Practices and Rehabilitation
- Vascular Malformations Diagnosis and Treatment
- Intraoperative Neuromonitoring and Anesthetic Effects
- Cervical and Thoracic Myelopathy
- Myasthenia Gravis and Thymoma
- Sarcoma Diagnosis and Treatment
- Musculoskeletal pain and rehabilitation
- Trigeminal Neuralgia and Treatments
- Hereditary Neurological Disorders
Universität Ulm
2016-2025
Bundeswehrkrankenhaus
2007-2024
Fachkrankenhaus Hubertusburg
2024
University Hospital Ulm
2009-2023
Klinik und Poliklinik für Neurologie
2017
Carl von Ossietzky Universität Oldenburg
2014
Klinik und Poliklinik für Psychiatrie und Psychotherapie
2009
Praxis für Humangenetik
2003
Kohler (New Zealand)
2003
Deutsche Nationalbibliothek
2003
The purpose of this study was to discover the number and types iatrogenic nerve injuries that were surgically treated during a 9-year period at relatively busy center. specific nerves involved, their sites injury, mechanisms injury also documented.The authors retrospectively evaluated lesions by reviewing case histories, operative reports, follow-up notes in 722 cases trauma. These between January 1990 December 1998 because pain, dysesthesias, sensory and/or motor deficits. latrogenic much...
Suprascapular nerve entrapment (SNE) in the suprascapular notch is a rare entity that must be considered differential diagnosis of radicular pain, as well shoulder discomfort. Over period 10 years (1985-1995), authors treated 28 cases SNE 27 patients by surgical decompression nerve. One patient underwent operation bilaterally within 5 years. Five presented with history trauma to region. In three patients, ganglion cyst was origin lesion. 16 problem primarily related athletic activities....
Little is known about patient satisfaction and disability after brachial plexus surgery. Would patients undergo the procedure again, if they knew current result beforehand? How do rate their disability?Of 319 who had undergone surgery between 1995 2005, 199 received a 65-item questionnaire. Measurement instruments included new plexus-specific outcome questionnaire (Ulm Questionnaire) with categories of satisfaction, functionality, pain, comorbidities, work; arm, shoulder, hand (DASH; scale,...
Surgical treatment of nerve lesions in continuity remains difficult, even the most experienced hands. The regenerative potential those injuries can be evaluated by intraoperative electrophysiological studies and/or intraneural dissection. present study examines value high-frequency ultrasound as an imaging tool for decision making management traumatic continuity.Intraoperative was applied to 19 or iatrogenic differing extents. information obtained correlated with electrophysiological,...
Background: This study aims to analyze potential risk factors that may influence the clinical outcomes following surgical treatment of traumatic peroneal nerve lesions. Methods: We conducted a retrospective analysis patients with injuries treated decompression, split repair, or grafting between 2010 and 2020. Motor function were evaluated. Results: Out 93 patients, 42 (45%) underwent 15 (16%) received 36 (39%) required autologous grafting. Up one year after surgery, weakness anterior tibial...
BACKGROUND: The safety of fibrin tissue adhesives has been a concern since they entered wide clinical application. Most commercially available kits contain the proteolytic inhibitor, aprotinin, to stabilize clot. A bovine protein, this substance an allergenic potency. CASE REPORT: This case report presents patient who had generalized allergic skin reaction, probably triggered by aprotinin upon reexposure sealant injected subgaleally achieve closure liquor fistula after neurosurgical...
Surgical therapy for traumatic brachial plexus lesions is still a great challenge in the field of peripheral nerve surgery. The aim this study was to present results different surgical interventions patients with lesion type.One hundred thirty-four underwent surgery between January 1991 and September 1999. In more than 50% patients, injury caused by motorbike accident. Patients mean 6.3 months posttrauma. following techniques were applied: neurolysis continuity (27 cases), grafting...
OBJECTIVE Facial nerve paresis and hearing loss are common complications after vestibular schwannoma surgery. Experiments with facial nerves of the rat retrospectively analyzed clinical studies showed a beneficial effect vasoactive treatment on preservation cochlear functions. This prospective open-label randomized pilot study is first prophylactic in METHODS Thirty patients were before One group (n = 14) received prophylaxis consisting nimodipine hydroxyethylstarch which was started day...
Posterior tarsal tunnel syndrome is an uncommon clinical entity which sometimes misdiagnosed in patients with pain of the retromalleolar region and plantar aspect foot. Surgical intervention recommended for correctly diagnosed posterior syndrome.Selective literature review.Surgical treatment indicated presence dysesthesias refractory to conservative or neurological deficits. If a neural tumor ganglion suspected, diagnostic imaging (MRI, neurosonography) should precede surgery. Division...
OBJECTIVE In this study, we compare different surgical procedures regarding the functional outcome of traumatic peroneal nerve lesions. METHODS a retrospective 48 patients with lesions (17 iatrogenic) were evaluated. Twenty-two presented in continuity displaying regenerative potential by action recording. these cases, surgery was restricted to either external (12÷) or interfascicular neurolysis (10÷). cases had no (10÷) showed discontinuity and thus reconstructed autologous sural grafts....
Abstract Global gene expression profiling was performed using RNA from adult human hippocampus-derived neuroprogenitor cells (NPCs) and multipotent frontal cortical fetal NPCs compared with mesenchymal stem (hMSCs) as a cell control, hippocampal tissue, to define pattern that is specific for NPCs. The results were data various databases. Hierarchical cluster analysis of all neuroectodermal cell/tissue types revealed strong relationship white matter tissues, whereas strongly correlate brain...
The diagnostic workup and surgical therapy for peripheral nerve tumors tumorlike lesions are challenging. Magnetic resonance imaging is the standard tool in preoperative workup. However, even with advanced pulse sequences such as diffusion tensor MR neurography, ability to differentiate tumor entities based on histological features remains limited. In particular, rare different from schwannomas neurofibromas difficult anticipate before exploration confirmation. High-resolution ultrasound...
Abstract Neurogenesis in the adult human brain occurs within two principle neurogenic regions, hippocampus and subventricular zone (SVZ) of lateral ventricles. Recent reports demonstrated isolation neuroprogenitor cells (NPCs) from these but due to limited tissue availability knowledge their phenotype differentiation behavior is restricted. Here we characterize capacity hippocampal NPCs (hNPCs), derived patients who underwent epilepsy surgery, on various feeder including fetal mixed cortical...
The aim of this study is to analyse short- and long-term results after surgical treatment foramen magnum meningiomas identify the possible advantages posterior suboccipital approach over lateral anterior approaches. Between 1992 2006, 16 patients with were operated on in our institution, all cases a was utilised extension bone opening according position tumour. In 14 patients, intraoperative monitoring lower cranial nerves performed. Localisation tumours ventral (3), ventrolateral (10),...
A pilot study of prophylactic nimodipine and hydroxyethyl starch treatment showed a beneficial effect on facial cochlear nerve preservation following vestibular schwannoma (VS) surgery. prospective Phase III trial was undertaken to confirm these results.An open-label, 2-arm, randomized parallel group multicenter with blinded expert review performed included 112 patients who underwent VS surgery between January 2010 February 2013 at 7 departments neurosurgery investigate the efficacy safety...
Abstract Mammals differ in their regeneration potential after traumatic injury, which might be caused by species-specific programs. Here, we compared murine and human Schwann cell (SC) response to injury developed an ex vivo model employing surgery-derived sural nerves. Transcriptomic lipid metabolism analysis of SCs following nerves revealed down-regulation lipogenic genes regulator metabolism, including Pparg (peroxisome proliferator-activated receptor gamma) S1P (sphingosine-1-phosphate)....