Zuchao Gu

ORCID: 0000-0002-1806-8754
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About
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Research Areas
  • Pelvic and Acetabular Injuries
  • Spinal Fractures and Fixation Techniques
  • Bone fractures and treatments
  • Hip and Femur Fractures
  • Spine and Intervertebral Disc Pathology
  • Medical Imaging and Analysis
  • Bone health and osteoporosis research
  • Shoulder and Clavicle Injuries
  • Bone Metabolism and Diseases
  • Shoulder Injury and Treatment
  • Scoliosis diagnosis and treatment
  • Orthopaedic implants and arthroplasty
  • Estrogen and related hormone effects
  • Molecular Biology Techniques and Applications
  • Radiation Dose and Imaging
  • Bone health and treatments
  • RNA Research and Splicing
  • Elbow and Forearm Trauma Treatment
  • Trauma Management and Diagnosis
  • Artificial Intelligence in Healthcare and Education
  • Congenital heart defects research
  • Natural product bioactivities and synthesis
  • Metabolomics and Mass Spectrometry Studies
  • Inflammatory mediators and NSAID effects
  • Pediatric Hepatobiliary Diseases and Treatments

First Affiliated Hospital of Chengdu Medical College
2018-2024

Integrated Chinese Medicine (China)
2020

Fourth People's Hospital of Sichuan Province
2015

Chengdu Women's and Children's Central Hospital
2014

Objective. Idiopathic scoliosis is the most common pediatric spinal deformity affecting 1% to 3% of population, and adolescent idiopathic (AIS) accounts for approximately 80% these cases; however, etiology pathogenesis AIS are still uncertain. The current study aims identify relationship between calmodulin 1 (CALM1) gene predisposition, genotypes SNPs clinical phenotypes AIS. Methods. 146 patients healthy controls were enrolled into this case-control study. 12 single nucleotide polymorphisms...

10.1155/2014/168106 article EN BioMed Research International 2014-01-01

Abstract A convenient method to evaluate bone cement distribution following vertebral augmentation is lacking, and therefore so our understanding of the optimal distribution. To address these questions, we conducted a retrospective study using data from patients with single-segment fracture who were treated at two hospitals. Five evaluation methods based on X-ray film compared determine best Of 263 included, 49 (18.63%) experienced re-collapse vertebrae 119 (45.25%) new fractures during...

10.1038/s41598-020-73513-2 article EN cc-by Scientific Reports 2020-10-01

To investigate the influencing factors of fracture nonunion after intramedullary nailing for subtrochanteric fractures and to construct a risk assessment model.Based on multicenter retrospective analysis 251 patients, all patients were divided into modeling group verification group. In group, postoperative rate, general data, fracture-related factors, surgical reduction-related mechanical biological calculated, screened by univariate analysis. Logistic regression model was used multifactor...

10.1097/md.0000000000025274 article EN cc-by-nc Medicine 2021-03-23

It is unclear whether the sandwich vertebra, at higher risk of new symptomatic fractures (NSFs), and prophylactic augmentation might benefit patients with vertebrae.To compare fracture-free probabilities sandwich, ordinary-adjacent, non-adjacent vertebrae, identify predictors NSFs.Data were retrospectively analyzed for who had undergone vertebral resulting in vertebrae. NSF rates determined identified using Cox proportional hazard models.The analysis included 1408 untreated vertebrae (147...

10.1136/neurintsurg-2020-016985 article EN Journal of NeuroInterventional Surgery 2021-01-19

Abstract Objective This study aimed to explore the correlation between SRY-related high-mobility-group box gene 4 (SOX4) 3′ untranslated region (UTR) single nucleotide polymorphism (SNP) and osteoporosis susceptibility. Methods The recruited 330 patients (the case group) non-osteoporosis control in Sichuan Chengdu First People’s Hospital Zibo Central from August 2016 2019. Sanger sequencing was used analyze genotypes of SOX4 rs79958549, rs139085828, rs201335371 loci. Multi-factor...

10.1186/s13018-021-02454-x article EN cc-by Journal of Orthopaedic Surgery and Research 2021-05-18

To compare the clinical effects of cortical bone trajectory screws and traditional pedicle in posterior lumbar fusion.

10.12182/20240360205 article EN PubMed 2024-03-20

To investigate the effectiveness of open reduction and internal fixation for multiple injuries superior shoulder suspensory complex (SSSC) with coracoid process fracture.Between January 2014 October 2018, 22 patients SSSC fracture were treated by fixation. There 16 males 6 females, aged from 24 to 72 years an average age 36.6 years. 10 cases falling injury, 5 traffic accident 7 height injury. All them fresh closed injuries. The time injury operation ranged 2 17 days 6.9 days. Both X-ray film...

10.7507/1002-1892.201908098 article EN PubMed 2020-03-15

Introduction Xianlinggubao (XLGB) capsule is a traditional Chinese medicine, which approved by the State Food and Drug Administration (CFDA) for osteoarthritis (OA) osteoporosis (OP). However, as with complex ingredients, molecular mechanisms supporting therapeutic effects have not been explored. Material methods A network pharmacology-based approach was conducted to explore interactome among targets of XLGB active compounds. Results The herbs in contain 41 compounds 246 high score targets,...

10.5114/aoms.2020.92931 article EN cc-by-nc-sa Archives of Medical Science 2020-02-12

To compare the refracture risk between sandwich vertebrae and ordinary adjacent vertebrae, to explore factors related refracture.Retrospective analysis was performed on data of patients who received percutaneous vertebral augmentation (PVA) formed April 2015 October 2019. Of them, 115 were enrolled in study. There 27 males 88 females with an average age 73.9 years (range, 53-89 years). Univariate analyzed patients' general data, indexes, indexes. Survival for all untreated at T 4-L 5...

10.7507/1002-1892.202104060 article EN PubMed 2021-09-15

Objective To investigate the epidemiological characteristics of proximal ulnoradial fractures in eastern coast and western inland areas China from 2010 through 2011. Methods The data all inpatients outpatients with fracture were collected who had been treated 16 hospital 6 provinces area 15 hospitals January December 2011. The patients assigned into group A those B. concerning gender, age injury AO type compared between 2 groups. Results From 2010through 2011, a total 1, 889 31...

10.3760/cma.j.issn.1671-7600.2016.06.011 article EN 2016-06-15

To investigate the effectiveness of "hybrid" suture with en masse combined double-layer repair under arthroscopy in delaminated rotator cuff tear by comparison suture.Fifty-six patients tears met selection criteria between June 2020 and January 2022 were included study. Patients divided into two groups ( n=28) using a random number method. The trial group underwent arthroscopic combination suture. control arthroscopy. There was no significant difference P>0.05) terms gender, age, side, size,...

10.7507/1002-1892.202301034 article EN PubMed 2023-04-15

This study aimed to explore the relationship between time from percutaneous vertebral augmentation (PVA) until subsequent fracture and risk of new symptomatic fractures (NSFs) in untreated vertebrae at different distances "augmented vertebrae". METHODSPatients who underwent PVA for treatment osteoporotic compression West China Hospital Sichuan University May 2014 April 2019 were retrospectively recruited.Vertebrae not treated during stratified based on their distance nearest augmented...

10.4274/dir.2023.221424 article EN cc-by-nc Diagnostic and Interventional Radiology 2023-08-09

To investigate the effectiveness of closed or limited open reduction and intramedullary nail fixation in treatment Seinsheimer type Ⅴ subtrochanteric fracture.Between May 2014 July 2018, 36 patients with Scinsheimer fractures were treated fixation. There 25 males 11 females an age 23-86 years (mean, 55.8 years). The cause injury included falling 19 cases, traffic accident 9 from height 7 heavy object 1 case; all fresh injuries. interval between operation was 1-14 days 6.8 days). 18 cases...

10.7507/1002-1892.201908100 article EN PubMed 2020-04-15

To investigate the effectiveness of volar oblique T-type locking plate and raft screws reduction fixation in treatment extreme distal radius fractures.Between July 2014 2018, 15 patients with fractures were treated fixation. There 6 males 9 females, aged from 30 to 66 years an average age 56.6 years. The cause injury was falling height 2 cases 13 cases. All them fresh closed injuries. rated as type 23C1 8 23C2 7 according AO/Orthopaedic Trauma Association (AO/OTA) classification. ulnar...

10.7507/1002-1892.201911108 article EN PubMed 2020-07-15
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