A5023429180- MRI in cancer diagnosis
- Radiomics and Machine Learning in Medical Imaging
- Advanced MRI Techniques and Applications
- Advanced Neuroimaging Techniques and Applications
- Fetal and Pediatric Neurological Disorders
- Bone and Joint Diseases
- Congenital Diaphragmatic Hernia Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Medical Imaging Techniques and Applications
- Head and Neck Cancer Studies
- Ovarian cancer diagnosis and treatment
- Liver Disease Diagnosis and Treatment
- Prostate Cancer Diagnosis and Treatment
- Pediatric Urology and Nephrology Studies
- Sarcoma Diagnosis and Treatment
- Neonatal Respiratory Health Research
- Congenital Anomalies and Fetal Surgery
- Salivary Gland Disorders and Functions
- Endometrial and Cervical Cancer Treatments
- Prostate Cancer Treatment and Research
- Cancer, Hypoxia, and Metabolism
- Atomic and Subatomic Physics Research
- Advanced X-ray and CT Imaging
- Digital Radiography and Breast Imaging
- Lung Cancer Diagnosis and Treatment
KU Leuven
2016-2025
Universitair Ziekenhuis Leuven
2005-2024
Maastricht University
2022
RWTH Aachen University
2022
Universitätsklinikum Aachen
2022
University of Brescia
2021
Ghent University Hospital
2017
Vlaams Patiëntenplatform
2017
University of Antwerp
2014
iMinds
2014
PURPOSE: To prospectively evaluate feasibility of diffusion-weighted (DW) magnetic resonance (MR) imaging in assessment renal function healthy volunteers and patients with various abnormalities to reproducibility DW MR volunteers. MATERIALS AND METHODS: Study protocol was approved by local ethics committee; informed consent obtained. Eighteen 15 underwent transverse fat-saturated echo-planar the kidneys during normal breathing. Freehand regions interest were delineated cortex medulla...
To assess the diagnostic accuracy of diffusion kurtosis magnetic resonance imaging parameters in grading gliomas.The institutional review board approved this prospective study, and informed consent was obtained from all patients. Diffusion parameters-mean diffusivity (MD), fractional anisotropy (FA), mean kurtosis, radial axial kurtosis-were compared solid parts 17 high-grade gliomas 11 low-grade (P<.05 significance level, Mann-Whitney-Wilcoxon test, Bonferroni correction). MD, FA, tumors...
Purpose: To evaluate diffusion-weighted (DW) magnetic resonance (MR) imaging, as compared with turbo spin-echo MR for the detection of nodal metastases in head and neck squamous cell carcinoma (HNSCC). Materials Methods: The study was approved by ethics committee, patients gave written informed consent. Before undergoing surgery, 33 consecutive underwent 1.5-T including DW imaging performed a wide range b values (0–1000 sec/mm2). apparent diffusion coefficients (ADCs) lymph nodes 4 mm or...
Comparative reviews of whole-body magnetic resonance imaging (WB-MRI) and positron emission tomography/computed tomography (CT; with different radiotracers) have shown that metastasis detection in advanced cancers is more accurate than currently used CT bone scans. However, the ability WB-MRI tomography/CT to assess therapeutic benefits has not been comprehensively evaluated. There also considerable variability availability quality WB-MRI, which an impediment clinical development. Expert...
Purpose: To prospectively evaluate feasibility and reproducibility of diffusion-weighted (DW) blood oxygenation level–dependent (BOLD) magnetic resonance (MR) imaging in patients with renal allografts, as compared these features healthy volunteers native kidneys. Materials Methods: The local ethics committee approved the study protocol; provided written informed consent. Fifteen a allograft stable condition (nine men, six women; age range, 20–67 years) 15 age- sex-matched underwent DW BOLD...
The purpose of this work was to evaluate the potential functional imaging with <sup>18</sup>F-FDG PET, <sup>18</sup>F-fluoromisonidazole diffusion-weighted MRI, and dynamic contrast-enhanced MRI provide an appropriate reliable biologic target for dose painting in radiotherapy head neck squamous cell carcinoma (HNSCC). <b>Methods:</b> Fifteen patients locally advanced HNSCC, treated concomitant chemoradiotherapy, were prospectively enrolled a bioimaging protocol. Sequential PET...
Abstract Purpose: To prospectively evaluate multiparametric magnetic resonance imaging (MRI) for accurate localization of intraprostatic tumor nodules, with whole‐mount histopathology as the gold standard. Materials and Methods: Seventy‐five patients biopsy‐proven, intermediate, high‐risk prostate cancer underwent preoperative T2‐weighted (T2w), dynamic contrast‐enhanced (DCE) diffusion‐weighted (DW) MRI at 1.5T. Localization suspicious lesions was recorded each 24 standardized regions...
Applications of diffusion-weighted (DW) magnetic resonance (MR) imaging outside the brain have gained increasing importance in recent years. Owing to technical improvements MR units and faster sequences, need for noninvasive without contrast medium administration, mainly patients with renal insufficiency, can be met successfully by applying this technique. DW is quantified apparent diffusion coefficient (ADC), which provides information on perfusion simultaneously. By using a biexponential...
To investigate the use of FDG-PET/CT before, during and after chemoradiotherapy (CRT) diffusion-weighted magnetic resonance imaging (DW-MRI) before CRT for prediction pathological response (pCR) in rectal cancer patients.Twenty-two patients treated with long course were included. An was performed prior to start CRT, 10 12 fractions five weeks end CRT. The tumor delineated using a gradient based delineation method maximal standardized uptake values (SUV(max)) calculated. A DW-MRI Mean...
Purpose To evaluate the effects of exposure to routine magnetic resonance (MR) imaging at 1.5 T during pregnancy on fetal growth and neonatal hearing function in relation dose timing utero a group newborns low risk for congenital impairment or deafness. Materials Methods This retrospective case-control study was approved by local ethics committee, written informed consent waived. Between January 2008 December 2012, 751 neonates exposed MR control subjects comprising 10 042 nonexposed...
Correct staging of patients with colorectal cancer is utmost importance for the prediction operability. Although computed tomography (CT) has a good overall performance, estimation peritoneal spread known weakness, problem that cannot always be overcome by Fluorine-18 fluorodeoxyglucose positron emission tomography/computed (18F-FDG-PET/CT); especially in infiltrative and miliary disease spread. Due to its high spatial contrast resolution magnetic resonance imaging (MRI) diffusion-weighted...
To compare dynamic contrast material-enhanced magnetic resonance (MR) imaging and diffusion-weighted MR for noninvasive evaluation of early late effects a vascular targeting agent in rat tumor model.The study protocol was approved by the local ethics committee animal care use. Thirteen rats with one rhabdomyosarcoma each flank (26 tumors) underwent contrast-enhanced echo-planar 1.5-T unit before intraperitoneal injection combretastatin A4 phosphate at (1 6 hours) later (2 9 days) follow-up...
PURPOSE: To evaluate diffusion-weighted magnetic resonance (MR) imaging for monitoring tumor response in rats after administration of combretastatin A4 phosphate. MATERIALS AND METHODS: Study protocol was approved by local ethical committee animal care and use. Rhabdomyosarcomas implanted subcutaneously both flanks 17 were evaluated with 1.5-T MR unit using four-channel wrist coil. Transverse T2-weighted fast spin-echo sequences, T1-weighted sequences before gadodiamide administration,...
To investigate the use of diffusion-weighted (DW) imaging for differentiating benign lesions from malignant pleural disease (MPD) and to retrospectively assess dynamic contrast material-enhanced (DCE) magnetic resonance (MR) acquisitions find out whether combining these measurements with DW could improve diagnostic value imaging.This study was approved by local ethics committee, all patients provided written informed consent. Thirty-one consecutive abnormalities suspicious MPD underwent...