A5062837223- Prostate Cancer Diagnosis and Treatment
- Advanced Radiotherapy Techniques
- Prostate Cancer Treatment and Research
- Head and Neck Cancer Studies
- Medical Imaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Bladder and Urothelial Cancer Treatments
- MRI in cancer diagnosis
- Head and Neck Surgical Oncology
- Radiopharmaceutical Chemistry and Applications
- Management of metastatic bone disease
- Urinary and Genital Oncology Studies
- Oral health in cancer treatment
- Lung Cancer Diagnosis and Treatment
- Cancer Genomics and Diagnostics
- Cancer Diagnosis and Treatment
- Cancer Immunotherapy and Biomarkers
- Esophageal Cancer Research and Treatment
- Salivary Gland Disorders and Functions
- Advanced MRI Techniques and Applications
- Cancer, Hypoxia, and Metabolism
- Bone and Joint Diseases
- Sinusitis and nasal conditions
- Radiation Therapy and Dosimetry
- Urological Disorders and Treatments
Iridium Kankernetwerk
2016-2025
University of Antwerp
2016-2023
GZA Ziekenhuizen Campus Sint-Augustinus
2017-2020
University of Sheffield
2020
GTx (United States)
2020
Erasmus MC
2019
HistoGeneX (Belgium)
2019
Technical University of Munich
2018
KU Leuven
2006-2015
Puigvert Foundation
2015
Purpose: To evaluate diffusion-weighted (DW) magnetic resonance (MR) imaging, as compared with turbo spin-echo MR for the detection of nodal metastases in head and neck squamous cell carcinoma (HNSCC). Materials Methods: The study was approved by ethics committee, patients gave written informed consent. Before undergoing surgery, 33 consecutive underwent 1.5-T including DW imaging performed a wide range b values (0–1000 sec/mm2). apparent diffusion coefficients (ADCs) lymph nodes 4 mm or...
Importance Although immune checkpoint inhibitors (ICIs) targeting programmed cell death 1 (PD-1) and PD-1 ligand have improved the outcome for many cancer types, majority of patients fails to respond ICI monotherapy. Hypofractionated radiotherapy has potential improve therapeutic ratio ICIs. Objective To assess addition ICIs compared with monotherapy in advanced solid tumors. Design, Setting, Participants This open-label, multicenter, randomized phase 2 trial was conducted 5 Belgian...
The purpose of this work was to evaluate the potential functional imaging with <sup>18</sup>F-FDG PET, <sup>18</sup>F-fluoromisonidazole diffusion-weighted MRI, and dynamic contrast-enhanced MRI provide an appropriate reliable biologic target for dose painting in radiotherapy head neck squamous cell carcinoma (HNSCC). <b>Methods:</b> Fifteen patients locally advanced HNSCC, treated concomitant chemoradiotherapy, were prospectively enrolled a bioimaging protocol. Sequential PET...
Abstract Background Pelvic nodal recurrences are being increasingly diagnosed with the introduction of new molecular imaging techniques, like choline and PSMA PET-CT, in restaging recurrent prostate cancer (PCa). At this moment, there no specific treatment recommendations for patients limited different locoregional approaches currently used, mostly by means metastasis-directed therapies (MDT): salvage lymph node dissection (sLND) or stereotactic body radiotherapy (SBRT). Since majority...
Background and purposeOligometastatic prostate cancer is a new emerging treatment field with only few prospective randomized studies published so far. Despite the lack of strong level I evidence, metastasis-directed therapies (MDT) are widely used in clinical practice, mainly based on retrospective small phase 2 large difference across centers. Pending results ongoing trials, there clear need for more consistent indications radiotherapy practices.Material methodsA European Society...
Purpose. The study presents the implementation of a novel method for incorporating hypoxia information from PET-CT imaging into treatment planning and estimates efficiency various optimization approaches. Its focuses on feasibility optimizing plans based non-linear conversion PET images radiosensitivity maps uptake properties tracers used. Material methods. seven head-and-neck cancer patients were used to determine optimal dose distributions needed counteract radiation resistance associated...
Immunotherapeutic approaches have revolutionized oncological practice but are less evaluated in gynecological malignancies. PD-1/PD-L1 blockade cancers showed objective responses 13-17% of patients. This could be due to immunosuppressive effects exerted by tumors on the microenvironment and an altered tumor vasculature. In other malignancies, combining checkpoint with radiation delivers benefit that is believed abscopal effect. Addition immune modulation agents has also shown enhance...