A novel polarizer based on the dissolution‐dynamic nuclear polarization (DNP) method has been designed, built and tested. The differs from those previously described by being designed with sterile use intent compatible clinical use. main features are: (1) an integral, disposable fluid path containing all pharmaceuticals constituting a barrier, (2) closed‐cycle cryogenic system to eliminate consumption of liquid cryogens (3) multi‐sample increase throughput. consists vial agent be polarized,...

The aim of this study was to compare the effects intermittent cold-water immersion and massage on perceptual performance markers recovery by basketball players after competitive matches. Eight men (age 23 ± 3 years; stature 190.5 8.9 cm; body mass 90.3 9.6 kg; fat 12.8 4.8%) eight women 22 2 179.0 8.5 77.6 9.2 22.5 6.6%) participated. Massage, or control were applied immediately matches, followed assessments measures physical performance, countermovement jump repeated-sprint ability 24 h...

The aim of this study was exploratory and sought to examine the effect on blood pressure (BP), heart rate (HR) mood state responses in primary school children moderate intensity cycling whilst viewing a green environment compared exercise alone. Following ethics approval parental informed consent, 14 (seven boys, seven girls, Mean age ± SD = 10 1 years) undertook two, 15 min bouts at counterbalanced order. In one bout they cycled film forest setting. other condition participants with no...

The 2011 English Elite Player Performance Plan (EPPP) stipulates training volumes that could put elite youth players at high risk of non-functional overreaching. aim the study was to assess player perceptions well-being and physical performance these loads. Fourteen academy football (mean ± SD: age 17 1 years; stature 179 6 cm; body mass 70.8 8.6 kg, pre-season) completed a perception questionnaire 1-4 times per week throughout each block (pre-season, in-season 1, 2, 3). Physical tests were...

Oral carbohydrate (CHO) rinsing has beneficial effects on endurance performance and caffeine (CAF) mouth either independently or in conjunction with CHO may enhance sprinting performance. However, the of CAF rinses resistance exercise have not been examined previously. The purpose this study was to investigate maximum strength muscular Fifteen recreationally resistance-trained males completed an protocol, which involved a 1 repetition (RM) bench press followed by 60% their 1RM failure...

In March 2020, the spreading Coronavirus (COVID-19) prompted United Kingdom government to introduce a societal shutdown, accompanied by self-isolation and social-distancing measures reduce virus transmission. doing so, opportunities for physical activity were likely reduced, potentially causing detrimental effects older adults. Therefore, present study investigated influence of initial six weeks lockdown on levels, perceived function mood in A cross-sectional, mixed-methods, observational...

MutY is an adenine-DNA glycosylase with specificity for mismatches involving 8-oxoguanine (oG.A) or guanine (G.A). In addition to a 25 kDa catalytic domain common all members of its DNA superfamily, has 14 C-terminal domain. Sequence analyses suggest that this distantly related MutT, pyrophosphohydrolase specific 2'-deoxy-8-oxoguanosine triphosphate (doGTP). Here we present biochemical evidence the MutT-like principal determinant oG specificity. First, dissociates approximately 1500-fold...

Abstract Hydrophobic side chains often are buried in the interior of a protein, and evolutionarily related proteins usually maintain hydrophobic character position. In this paper we shown that pattern hydrophobicity values derived from set protein sequences is well correlated with linear side‐chain solvent accessibility values, calculated known structure representative sequences. several cases, information aligned can be used to select correct tertiary fold large database structures.

This study examined the effect of short duration, moderate and high-intensity exercise on a Go/NoGo task. Fifteen, habitually active (9 females 6 males aged 28 ± 5 years) agreed to participate in cognitive performance was measured three sessions lasting 10 min each, performed at different intensities: rest, high. Results indicated significant intensity main effects for reaction time (RT) (p = 0.01), omission error rate 0.027) decision 0.011), with significantly longer RTs during high...

Abstract Richardson, DL and Clarke, ND. Effect of coffee caffeine ingestion on resistance exercise performance. J Strength Cond Res 30(10): 2892–2900, 2016—The aim the present study was to determine effect ingesting dose-matched anhydrous caffeine, coffee, or decaffeinated plus during Nine resistance-trained men (mean ± SD : age, 24 2 years; weight, 84 8 kg; height, 180 cm) completed a squat bench press protocol at 60% 1 repetition maximum until failure 5 occasions consuming 0.15 g·kg −1...

Over the past 20 years, monitoring in soccer has become increasingly popular for managing training loads, preventing injuries, and optimizing performance. However, implementing sophisticated systems demands substantial investment equipment, staff training, athlete time. The present study aimed to evaluate player's perceptions around a comprehensive programme used within professional English men's team. A mixed-methods sequential explanatory design was employed across two phases. In Phase...

Escherichia coli MutY is a 39 kDa adenine DNA glycosylase and 3' apurinic/apyrimidinic (AP) lyase that active on substrates containing A/G, A/C, or A/8-oxoG mismatches. 8-oxoG (7,8-dihydro-8-oxoguanine GO) major stable product of oxidative damage, A/GO mismatches may be particularly important biological for MutY. Proteolytic digestion using thermolysin was found to produce two relatively fragments 25 12 kDa. The fragment begins at the N terminus spans region homologous with E. endonuclease...

A total of 77 children (34 boys, 43 girls, mean age ± standard deviation = 9 1 years) participated in this study; 46 (intervention) undertook a 12-week school gardening programme and 31 acted as controls. Measures the Theory Planned Behaviour fruit vegetable consumption were taken pre- post-intervention. Repeated measures analysis variance hierarchical regression indicated that intervention group increased daily fruits vegetables intentions, attitudes, norms, perceived behavioural control...

The purpose of this study was to investigate the effect a simulated soccer test on functional hamstrings‐to‐quadriceps ratio ( H ecc : Q con ) in female players. Fourteen amateur players (age, 26.1 ± 4.6 years; height, 168 12 cm; body mass, 62.7 5.5 kg; fat, 23.7 2.2%) performed modified L oughborough I ntermittent S huttle T est (modified LIST ). Isokinetic strength assessments hamstrings and quadriceps dominant non‐dominant legs at 120°/s were before immediately after . calculated as peak...

The aim of this study was to investigate the effect incorporating stretches into a massage recovery treatment after competitive basketball match on perceptual and physical markers recovery. Nine men (age: 22 ± 3 years; stature: 191.2 8.5 cm; body mass: 90.9 10.1 kg; fat: 12.4 4.7%) 8 women 21 176.4 8.1 73.9 9.7 21.9 5.5%) who are national-level players received massage, stretching, or no immediately match. perception overall fatigue leg soreness assessed 24 hours later, whereas...

This study examined the effects of changes in physiological and psychological arousal on badminton short-serve performance competitive practice climates. Twenty players (10 males 10 females) volunteered to participate following ethics approval. After familiarisation, was measured at rest, mid-way through end a badminton-specific exercise protocol two conditions; competition vs. practice. Ratings cognitive somatic anxiety were assessed three time points prior using Mental Readiness Form 3....