A5009745129- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer Mechanisms and Therapy
- Liver physiology and pathology
- Liver Disease Diagnosis and Treatment
- Cancer Research and Treatments
- Ubiquitin and proteasome pathways
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pediatric Hepatobiliary Diseases and Treatments
- Liver Disease and Transplantation
- Lung Cancer Treatments and Mutations
- Circular RNAs in diseases
- Gallbladder and Bile Duct Disorders
- Acute Myeloid Leukemia Research
- MicroRNA in disease regulation
- Pancreatic and Hepatic Oncology Research
- NF-κB Signaling Pathways
- Autophagy in Disease and Therapy
- Histone Deacetylase Inhibitors Research
- Bioactive Compounds and Antitumor Agents
University of Science and Technology of China
2019-2025
Anhui Provincial Hospital
2019
Liver venous deprivation (LVD; simultaneous portal vein embolization and hepatic embolization) has been the latest surgical strategy for rapid future liver remnant (FLR) hypertrophy. The aim of this study was to assess feasibility, safety, efficacy LVD following arterial chemoembolization (TACE-LVD) before major hepatectomy hepatocellular carcinoma (HCC). A retrospective analysis outcomes 23 HCC patients who underwent TACE-LVD at our center between October 2019 2023 conducted. An assessment...
γ-Tocotrienol (γ-T3) exhibits the activity of anticancer via regulating cell signaling pathways. Nuclear factor-κB (NF-κB), one crucial pro-inflammatory factors, is involved in regulation proliferation, apoptosis, invasion, and migration tumor. In present study, NF-κB inhibited by γ-T3 was investigated gastric cancer cells. Cell activity, active protein phosphatase type 2A (PP2A), ataxia-telangiectasia mutated (ATM) were explored using 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium...
To date, carbohydrate antigen 19-9 (CA19-9) and carcinoembryonic (CEA) have been widely used for the screening, diagnosis prediction of biliary tract cancer (BTC) patients. However, few studies with large sample sizes 50 (CA50) were reported in BTC
Leukemia is a life-threatening malignant tumor of the hematopoietic system. Currently, main treatment modalities are chemotherapy and stem cell transplantation. However, increased drug resistance due to decreased sensitivity leukemia cells chemotherapeutic drugs presents major challenge in current treatments. Autophagy-associated proteins involved autophagy initiation have now been shown be development various types associated with resistance. Therefore, this review will explore roles...
e15129 Background: The implementation of adjuvant therapy in reducing tumor recurrence hepatocellular carcinoma (HCC) is an essential approach for extending the prognosis patients. exploration treatment strategies that are both efficacious and secure remains a prominent area research recent years. Donafenib novel, oral, small-molecule, multikinase inhibitor, has demonstrated promising efficacy safety profiles preclinical clinical studies. However, there currently lack reported data on...
Background: Adjuvant therapy is used to reduce the risk of hepatocellular carcinoma (HCC) recurrence and improve patient prognosis. Exploration treatment strategies that are both efficacious safe has been extensively performed in recent years. Although donafenib demonstrated good efficacy advanced HCC, its use as adjuvant HCC not reported. Objectives: To investigate safety postoperative patients with at high-risk recurrence. Design: Retrospective study. Methods: A total 196 were included...
Hepatocellular adenoma is a rare type of benign tumor in the liver. It has high risk rupture and low malignant transform. Recently incidence hepatocellular transforming been increasing. The progress develop to carcinoma transition state. This course not only relyes on CTNNB1 gene exon 3 mutations, but also depends TERT promoter mutation. article will elaborate molecule mechanism, pathological diagnosis therapies. Key words: Adenoma, liver cell; Mechanism; Genes, TERT; β-catenin