Jun He

ORCID: 0000-0002-1963-9766
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About
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Research Areas
  • Animal Nutrition and Physiology
  • Gut microbiota and health
  • Adipose Tissue and Metabolism
  • Meat and Animal Product Quality
  • Probiotics and Fermented Foods
  • Animal Behavior and Welfare Studies
  • Muscle Physiology and Disorders
  • Exercise and Physiological Responses
  • Viral gastroenteritis research and epidemiology
  • Antimicrobial Peptides and Activities
  • Immune Response and Inflammation
  • Diet and metabolism studies
  • Infant Nutrition and Health
  • Animal Virus Infections Studies
  • Sirtuins and Resveratrol in Medicine
  • Ruminant Nutrition and Digestive Physiology
  • Phytoestrogen effects and research
  • Biofuel production and bioconversion
  • Rabbits: Nutrition, Reproduction, Health
  • Birth, Development, and Health
  • Clostridium difficile and Clostridium perfringens research
  • Aquaculture disease management and microbiota
  • Enzyme Production and Characterization
  • Protein Hydrolysis and Bioactive Peptides
  • Muscle metabolism and nutrition

Sichuan Agricultural University
2016-2025

Ministry of Agriculture and Rural Affairs
2019-2025

Yunnan Agricultural University
2023-2025

Ministry of Education of the People's Republic of China
2014-2024

Thomas Jefferson University
2024

Zhejiang University
2024

Anhui Normal University
2024

Wannan Medical College
2024

Foshan University
2024

Tianjin University of Traditional Chinese Medicine
2024

The objective of the present study was to evaluate effects fibre source on intestinal mucosal barrier function in weaning piglets. A total 125 piglets were randomly allotted basis their body weight and litters one five experimental diets, i.e. a control diet without (CT), diets which expanded maize replaced by 10 % (MF), soyabean (SF), wheat bran (WBF) or pea (PF). water fed ad libitum for 30 d. Piglets WBF PF had lower diarrhoea incidence compared with MF- SF-fed animals. higher ratio...

10.1017/s0007114513001293 article EN British Journal Of Nutrition 2013-05-09

10.1016/j.bbrc.2012.05.106 article EN Biochemical and Biophysical Research Communications 2012-05-26

Rapeseed cake is a good source of protein for animal feed but its utilization limited due to the presence anti-nutritional substances, such as glucosinolates (Gls), phytic acid, tannins etc. In present study, solid state fermentation (SSF) using Aspergillus niger was carried out with purpose degrading and improving nutritional quality rapeseed (RSC). The effects medium composition incubation conditions on Gls content in fermented (FRSC) were investigated, chemical amino acid vitro...

10.1186/s40104-015-0015-2 article EN cc-by Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology 2015-04-07

Abstract Obesity causes changes in microbiota composition and an altered gut can transfer obesity-associated phenotypes from donors to recipients. Obese Rongchang pigs (RP) exhibited distinct fiber characteristics lipid metabolic profiles their muscle compared with lean Yorkshire (YP). However, whether RP have a different than YP there is relationship between the properties are poorly understood. The present study was conducted test be transferred germ-free (GF) mice. High-throughput...

10.1038/srep31786 article EN cc-by Scientific Reports 2016-08-22

Chlorogenic acid (CGA) is a natural phenolic acid, which an important component of biologically active dietary phenols isolated from various species. Two experiments were conducted to investigate the effects CGA on growth performance, antioxidant capacity, nutrient digestibility, diarrhea incidence, intestinal digestion and absorption function, expression levels absorption-related genes in weaned pigs. In Exp. 1, 200 pigs randomly allotted four treatments fed with basal diet or supplemented...

10.1093/jas/skx078 article EN Journal of Animal Science 2018-03-01

Lactobacillus rhamnosus GG (LGG) has been regarded as a safe probiotic strain. The aim of this study was to investigate whether dietary LGG supplementation could alleviate diarrhea via improving jejunal mucosal barrier function in the weaned piglets challenged by RV, and further analyze potential roles for apoptosis cells intestinal microbiota. A total 24 crossbred barrows at 21 d age were assigned randomly 1 2 diets: basal diet supplementing diet. On day 11, all pigs orally infused RV or...

10.1371/journal.pone.0146312 article EN cc-by PLoS ONE 2016-01-04

Chitosan oligosaccharide (COS), an oligomer of<sc>d</sc>-glucosamine, is a vital growth stimulant in the pig industry.

10.1039/c7ra00142h article EN cc-by-nc RSC Advances 2017-01-01

Chlorogenic acid (CGA), an ester formed between caffeic and quinic acid, is one of the most abundant phenolic acids widespread in fruits, vegetables, cereals tuber crops. Therefore, present study was conducted to test hypothesis that dietary supplementation with CGA could improve intestinal health regulate selected microbiota weaned piglets. A total twenty-four piglets (21 d age) were randomly assigned four groups according their initial BW sex fed a basal diet (control group) or containing...

10.1039/c8fo01126e article EN Food & Function 2018-01-01

In recent years, the function of plant polyphenols to improve intestinal barrier has been fully demonstrated. However, exact mechanisms linking with have not yet established. Apple (APs) are safe and healthy nutrients, which extracted from apples their byproducts. Using pig IPEC-J2 cell models, this study investigated effects dietary AP supplementation on antioxidant capacity function. Then, we further explored role Nrf2/Keap1 signaling pathway in maintaining Our found that improved...

10.1021/acs.jafc.2c02495 article EN Journal of Agricultural and Food Chemistry 2022-06-09

Abstract Rotavirus is one of the pathogenic causes that induce diarrhea in young animals, especially piglets, worldwide. However, nowadays, there no specific drug available to treat disease, and related vaccines have obvious efficiency some countries. Via analyzing pathogenesis rotavirus, it inducing mainly due disturb enteric nervous system, destroy gut mucosal integrity, intracellular electrolyte imbalance, impair microbiota immunity. Many studies already proved prebiotics probiotics can...

10.1186/s40104-024-01018-3 article EN cc-by Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology 2024-05-03

Abstract The intestine plays key roles in maintaining body arginine (Arg) homoeostasis. Meanwhile, the is very susceptible to reactive oxygen species. In light of this, study aimed explore effects Arg supplementation on intestinal morphology, transporters and metabolism, potential protective mechanism piglets under oxidative stress. A total thirty-six weaned were randomly allocated six groups with replicates fed a base diet (0·95 % Arg,) or supplemented 0·8 1·6 l- for 1 week, respectively....

10.1017/s0007114517001519 article EN British Journal Of Nutrition 2017-06-14

As a organic acid, benzoic acid has become one of the most important alternatives for antibiotics, and its beneficial effect on performance in animals been proven decade. However, knowledge effects jejunal digestive physiology, especially antioxidant capacity mucosal glucagon-like peptide 2 (GLP-2) concentrations is lacking.A total 20 barrows [Duroc × (Yorkshire Landrace)] with an average body weight (BW) 18.75 ± 0.2 kg were used 14-d trial to determine potential mechanisms supplementation...

10.1186/s40104-016-0091-y article EN cc-by Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology 2016-05-28

Summary This study was conducted to investigate the effects of benzoic acid ( BA ) on growth performance, intestinal development and barrier function in weaned pigs. Ninety pigs were randomly assigned one three treatments: a basal diet CON ), supplemented with 2000 mg/kg 1) 5000 2). At end days 14 42, six per treatment selected collect plasma samples. Results showed that supplementation not only improved final body weight, daily feed conversion ratio from 15 42 1 but also decreased activity...

10.1111/jpn.12627 article EN Journal of Animal Physiology and Animal Nutrition 2016-10-16
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