A5052474448- Ovarian function and disorders
- Reproductive Biology and Fertility
- Obstructive Sleep Apnea Research
- Helicobacter pylori-related gastroenterology studies
- Pneumonia and Respiratory Infections
- Sperm and Testicular Function
- Lung Cancer Treatments and Mutations
- Neuroscience of respiration and sleep
- Meta-analysis and systematic reviews
- Assisted Reproductive Technology and Twin Pregnancy
- Respiratory viral infections research
- Childhood Cancer Survivors' Quality of Life
- Gastric Cancer Management and Outcomes
- Liver Disease Diagnosis and Treatment
- Machine Learning in Healthcare
- Pediatric health and respiratory diseases
- Metabolomics and Mass Spectrometry Studies
- Epigenetics and DNA Methylation
- Global Cancer Incidence and Screening
- Hypothalamic control of reproductive hormones
- Allergic Rhinitis and Sensitization
- Ovarian cancer diagnosis and treatment
- Microgrid Control and Optimization
- Acute Lymphoblastic Leukemia research
- Air Quality and Health Impacts
Beijing Children’s Hospital
2016-2025
Capital Medical University
2016-2025
Tianjin University
2022-2024
Center for Children
2023-2024
Beihang University
2019-2023
Peking University
2007-2023
Beijing Institute of Big Data Research
2019-2023
Capital University
2023
Peking University Third Hospital
2023
Beijing Obstetrics and Gynecology Hospital
2023
<h3>Objective</h3> <i>Helicobacter pylori</i> infection and overexpression of cyclo-oxygenase-2 (COX-2) are associated with gastric cancer its precursors. To evaluate the effect a selective COX-2 inhibitor alone combined <i>H eradication on evolution precancerous lesions, randomised, placebo-controlled trial was conducted in Linqu County, Shandong Province, China. <h3>Methods</h3> A total 1024 participants aged 35–64 years advanced lesions were randomly assigned factorial design to two...
Abstract Aberrant DNA methylation plays an important role in cancer progression. However, no resource has been available that comprehensively provides methylation-based diagnostic and prognostic models, expression–methylation quantitative trait loci (emQTL), pathway activity-methylation (pathway-meQTL), differentially variable methylated CpGs, survival analysis, as well functional epigenetic modules for different cancers. These provide valuable information researchers to explore profiles...
Background The known risk factors of childhood OSAS include tonsillar and adenoidhypertrophy, obesity, craniofacial anomalies, neuromuscular disorders African-American (AA) ancestry. Whether other such as allergic rhinitis (AR), premature, environmental tobacco smoking (ETS) are associated with inconsistent in different studies. Our study enrolled children a broad age range included potential derived from previous studies our own experience. objective is to identify clinical setting. Methods...
<p>Artificial Intelligence (AI) has transformed how we live and think, it will change practice medicine. With multimodal big data, can develop large medical models that enables what used to unimaginable, such as early cancer detection several years in advance effective control of virus outbreaks without imposing social burdens. The future is promising, are witnessing the advancement. That said, there challenges cannot be overlooked. For example, data generated often isolated difficult...
Purpose: No validated biomarkers that could identify the subset of patients with lung adenocarcinoma who might benefit from chemotherapy have yet been well established. This study aimed to explore potential biomarker model predictive efficacy and survival outcomes after first-line pemetrexed plus platinum doublet based on metabolomics profiling.Experimental Design: In total, 354 consecutive eligible were assigned receive in combination either cisplatin or carboplatin. Prospectively collected...
Abstract Background Acute gastroenteritis (AGE) causes significant morbidity in children worldwide; however, the disease burden of hospitalized with viral China has been rarely described. Through this study, we analyzed data to explore changes epidemiology and clinical characteristics mainland China. Methods Data were extracted from Futang Children's Medical Development Research Center (FRCPD), between 2016 2020, across 27 hospitals 7 regions. The demographics, geographic distribution,...
Futang Research Center of Pediatric Development (FRCPD), the first nonprofit social service organization engaging in pediatric research China, was founded May 2013. Until August 2021, FRCPD has 40 tertiary children's hospitals, accounting for about 65.6% all national public which reported to be 61 China Health Statistical Yearbook (2020). The hospitals are distributed 30 provinces, autonomous regions, and municipalities (except Tibet region), most them capital province, forming a broad...
Background Congenital TORCH ( Toxoplasma gondii (T . gondii) , rubella virus (RV), cytomegalovirus (CMV), and herpes simplex (HSV)) infections are associated with a variety of adverse prenatal neonatal events, including miscarriage, malformations developmental abnormalities, they remain an issue that cannot be neglected in China. However, the current research focuses more on general screening women childbearing age, medical information children hospitalized due to congenital perinatal has...
Pediatric tuberculosis (TB) is a serious infectious disease that affects many children worldwide and more likely to be extrapulmonary than adult TB. However, the clinical epidemiological profile, cost burden of pediatric TB (EPTB) in China remain unknown. Here, we conducted descriptive, multicenter study patients from 22 hospitals across all six regions October 2015 December 2018. Of 4,654 patients, 54.23% (2,524) had pulmonary (PTB), 17.76% (827) EPTB, 28.00% (1,303) concurrent (combined...
<p>Air pollution is a pressing concern in China, particularly its adverse effects on vulnerable populations such as children and adolescents. This study aimed to elucidate the disease burden adolescents attributable air geographical areas across China from 1990 2019. We used Global Burden of Diseases, Injuries, Risk Factors Study 2019 methodology estimate 33 including provinces, autonomous regions, municipalities, special administrative regions. In 2019, approximately 10,511 childhood...
To develop a clinical model for predicting the occurrence of Central Precocious Puberty based on breast development outcomes in chinese girls. This is retrospective study, which included total 1,001 girls aged 6-9 years old who visited outpatient clinic Beijing Children's Hospital from January 2017 to October 2022 "breast development". Participants were categorized into pubertal (PD) cohort and simple premature (PT) according criteria, information was collected tested relevant indicators....
To investigate the epidemiological profile and cost burden of pediatric inpatients with tuberculous meningitis (TBM) in China. We conducted a descriptive multicenter study involving TBM from 9 provincial hospitals 20 municipal across 24 provinces China January 2016 to December 2021. Sociodemographic geographic variables, admission discharge information were extracted face sheets medical records describe characteristics. Length hospital stay (LOS) hospitalization expenses used assess disease...
<p>Artificial intelligence (AI) is driving transformative changes in the field of medicine, with its successful application relying on accurate data and rigorous quality standards. By integrating clinical information, pathology, medical imaging, physiological signals, omics data, AI significantly enhances precision research into disease mechanisms patient prognoses. technologies also demonstrate exceptional potential drug development, surgical automation, brain-computer interface (BCI)...
Community acquired pneumonia (CAP) is a major global public health concern among children, with viral pathogens playing significant role. Despite this, national multicenter studies on community (VCAP) in hospitalized children remain scarce. The study employed approach to investigate the clinical epidemiology and burden of VCAP across China. Data were extracted from face sheets discharge medical records (FSMRs) within FuTang Update Medical Records (FUTURE) database, spanning 2016 2022. cases...
Hospitalized children experience mortality as a result of infections. Since the COVID-19 outbreak in early 2020, China's strict prevention measures have curbed pathogen transmission, altering infection-related epidemiology. The Futang Research Center Pediatric Development has collected face sheet discharge medical records (FSMRs) data from 27 tertiary children's hospitals since January 2016, which facilitate us to investigate this issue. Moreover, study focuses on hospitalized aged 18 years...