- Diabetes Management and Research
- Diabetes Treatment and Management
- Diabetes Management and Education
- Diabetes and associated disorders
- Diet and metabolism studies
- Diet, Metabolism, and Disease
- Pancreatic function and diabetes
- Nutrition, Health and Food Behavior
- Nutrition, Genetics, and Disease
- Consumer Attitudes and Food Labeling
- Metabolism, Diabetes, and Cancer
- Advanced Glycation End Products research
- Mobile Health and mHealth Applications
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Health and Wellbeing Research
- Sleep and related disorders
- Dietary Effects on Health
- Behavioral Health and Interventions
- Chronic Disease Management Strategies
- Liver Disease Diagnosis and Treatment
- Iron Metabolism and Disorders
- Physical Activity and Health
- Exercise and Physiological Responses
- Natural Antidiabetic Agents Studies
- Regulation of Appetite and Obesity
Kyoto Medical Center
2018-2025
Clinical Research Institute
2025
Murata (Japan)
2022
Chang Gung University of Science and Technology
2022
Seiko Holdings (Japan)
2022
National Hospital Organization
2022
Okayama Medical Center
2022
Osaka National Hospital
2022
Hyogo Chuo National Hospital
2022
University hospital Medical Information Network
2022
Background Commercial smartphone apps that promote self-monitoring of weight loss are widely available. The development disease-specific has begun, but there is no app for specific health guidance (SHG) to prevent metabolic syndrome, type 2 diabetes, and cardiovascular diseases in middle-aged adults Japan. Objective This study aimed determine the efficacy an SHG mobile facilitating Japanese with obesity hypertension. Methods In a 12-week, statistician-blinded, randomized parallel controlled...
Abstract Background: Falls are among the most prevalent workplace accidents, necessitating thorough screening for susceptibility to falls and customization of individualized fall prevention programs. The aim this study was develop validate a high risk prediction model using machine learning (ML) video-based first three steps in middle-aged workers. Methods: Train data (n=190, age 54.5±7.7 years, 48.9% male) validation (n=28, 52.3±6.0 53.6% were enrolled study. Pose estimation performed...
Omega-3 polyunsaturated fatty acids (n-3 PUFAs) have unique properties that benefit female athletes. No study has examined the association between dietary inflammatory index (DII) and omega-3 index. Therefore, we investigated DII This cross-sectional included university athletes age- sex-matched controls. Data were collected from anthropometric assessments, a food frequency questionnaire (FFQ), blood tests for lipidomics. The energy-adjusted was calculated using FFQ. Seventy-four (mean...
Brown adipose tissue (BAT) is responsible for non-shivering thermogenesis and an attractive therapeutic target combating obesity related diseases. Human BAT activity has been evaluated by 18F-fluorodeoxyglucose-positron emission tomography/computed tomography (18FDG-PET/CT) under acute cold exposure, but the method some serious limitations, including radiation exposure. Infrared thermography (IRT) may be a simple less-invasive alternative to evaluate activity. In present study, establish...
The discrepancy between HbA1c and glucose exposure may have significant clinical implications; however, the association hemoglobin glycation index (HGI) parameters in type 1 diabetes remains controversial. This study aimed to find factors associated with HGI (laboratory - predicted derived from continuous monitoring [CGM]).We conducted a cross-sectional of adults (n = 211, age 50.9 ± 15.2 years old, female sex 59.2%, duration CGM use 2.1 1.0 years). All subjects wore for 90 days before...
Background: Information about factors related to better adherence continuous glucose monitoring (CGM) sensor is quite limited. Materials and Methods: Forty-six participants with type 1 diabetes using subcutaneous insulin infusion (CSII) without CGM were recruited. The participants’ characteristics diabetes-related quality of life (QOL) evaluated at baseline one year after starting use CGM. Participants wearing the for ≥60% time considered as adherent. Results: mean age 46 was 44.1 ± 15.0...
Given the major role of glucose-dependent insulinotropic polypeptide (GIP) in regulation adiposity, this study examined effects induced by a diet based on Japanese tradition (SMART WASHOKU) visceral fat area (VFA) and GIP secretions.Overweight/obese men (n = 21; mean age, 41.0 ± 9.0 years; BMI, 25.2 2.0 kg/m2) without diabetes were placed either SMART WASHOKU or control meal for 2 weeks, randomized, cross-over setup with four-week washout period.For tolerance test, blood samples collected at...
Abstract Background Hypoglycemia in type 1 diabetes (T1D) is associated with mortality and morbidity, especially when awareness of hypoglycemia impaired. This study aimed to investigate the protective risk factors for impaired (IAH) adults T1D. Methods cross-sectional enrolled 288 T1D (mean age, 50.4 ± 14.6 years; male, 36.5%; duration, 17.6 11.2 mean HbA1c level, 7.7 0.9%), who were divided into IAH non-IAH (control) groups. A survey was conducted assess using Clarke questionnaire. Diabetes...
Objective Patients with type 1 diabetes (T1D) and impaired awareness of hypoglycemia (IAH) are at an elevated risk experiencing automobile accidents. We therefore investigated the association IAH driving safety problem-solving abilities in adults T1D. Methods This cross-sectional survey used Gold's method adult patients T1D National Hospital Organization (NHO) from February 14, 2020, to October 31, 2021. The participants were divided into control groups. data included information on...
Polycystic ovary syndrome (PCOS) is a common endocrine disorder among reproductive-aged women. While PCOS associated with an increased risk of obesity and insulin resistance, little known regarding the prevalence factors for nonalcoholic fatty liver disease (NAFLD) Japanese women PCOS. We estimated elevated enzymes, as index NAFLD, in PCOS.We retrospectively reviewed 102 who visited Department Gynecology, Kyoto Medical Center Japan from January 2000 to September 2016. Inclusion criterion was...
Lifestyle interventions have been shown to prevent or delay the onset of diabetes; however, inter-individual variability in responses such makes lifestyle recommendations challenging. We analyzed Japan Diabetes Outcome Intervention Trial-1 (J-DOIT1) study data using a previously published mechanistic simulation model type 2 diabetes and progression understand causes optimize dietary intervention strategies at an individual level. J-DOIT1, large-scale study, involved 2607 subjects with...
Background: Continuous subcutaneous insulin infusion (CSII) is associated with improved glycemic control, a reduced incidence of hypoglycemia, and quality life (QOL). To date, however, there has been no QOL scale specific to CSII. The objective this study was develop validate measure CSII-QOL for people type 1 diabetes (T1D). Methods: A total 50 T1D aged ≥15 years who used CSII (28% males; age, 47.6 ± 17.0 years; duration diabetes, 14.7 9.7 use, 6.1 3.3 HbA1c, 7.4% 0.8%) took part in the...
Introduction This study evaluated the impact of a telephone support programme with telemonitoring on changes in healthy eating and active exercise adults prediabetes using stage change framework. Methods We performed post hoc analysis data from Japan Diabetes Outcome Trial-1. A total 2607 participants aged 20–65 years impaired fasting glucose were recruited workplace/community randomized to one year intervention arm ( n = 1240) or self-directed control 1367). Participants both arms received...
Background: Evidence of the long-term benefits telephone-delivered lifestyle interventions is limited. This study investigated ability intervention to reduce incidence metabolic syndrome (MetS) in subjects diagnosed with impaired fasting glucose (IFG) during health checkups. Methods: Our were participants Japan Diabetes Outcome Intervention Trial-1 (J-DOIT1), a prospective, cluster-randomized controlled trial designed investigate whether goal-focused coaching over telephone can effectively...
Abstract Objectives Using annual health check-up data, the aim of this study was to identify target populations for lifestyle interventions effectively prevent diabetes in a real-world setting. Methods The Japan Diabetes Outcome Intervention Trial-1, prospective, cluster-randomized controlled trial, launched test if year-long telephone-delivered support by professionals can development type 2 (T2D) people with impaired fasting glucose (IFG) identified at check-ups. A total 2607 participants...
This study evaluated the association between psychological distress and development of type 2 diabetes (T2D) among male individuals in workplace.This observational cohort enrolled 6,326 participants aged 18 - 65 years (mean age 47.4 ± 9.5 years, body mass index 23.4 3.4 kg/m2, hemoglobin A1c 5.5±0.3%), who received annual health checkups from April 2016 to March 2017. Those had a level ≥ 6.5%, previous history diabetes, or used medication were excluded analysis. Psychological was measured...
Objectives: Limited understanding of the causes variability in individual response to similar lifestyle changes makes it challenging design individualized diet plans for diabetes prevention. We previously reported a simulation model disease and tested using data from DPP low carb-low fat crossover study. Here we used analyze J-DOIT1 understand optimize therapy. Methods: is large-scale intervention study 2,607 subjects with 5.5 year follow-up. selected 60 baseline-matched individuals placebo...