- Health Systems, Economic Evaluations, Quality of Life
- Dementia and Cognitive Impairment Research
- Geriatric Care and Nursing Homes
- Intensive Care Unit Cognitive Disorders
- Anesthesia and Sedative Agents
- Frailty in Older Adults
- Healthcare Policy and Management
- Patient-Provider Communication in Healthcare
- Cultural Competency in Health Care
- Childhood Cancer Survivors' Quality of Life
- Patient Satisfaction in Healthcare
- Ophthalmology and Visual Health Research
- Anesthesia and Neurotoxicity Research
- Prostate Cancer Diagnosis and Treatment
- Retinal and Optic Conditions
- Delphi Technique in Research
- Health disparities and outcomes
- Child and Adolescent Health
- Stroke Rehabilitation and Recovery
- Intimate Partner and Family Violence
- Adolescent and Pediatric Healthcare
- Acute Ischemic Stroke Management
- Infant Development and Preterm Care
- Clinical practice guidelines implementation
- Medical Malpractice and Liability Issues
London School of Hygiene & Tropical Medicine
2016-2025
Indiana University School of Medicine
2025
Indiana University – Purdue University Indianapolis
2025
New York Medical College
2020-2024
Creative Commons
2023
Westchester Medical Center
2020-2023
Brighton and Sussex Medical School
2014-2022
Faculty of Public Health
2012-2022
United States Military Academy
2022
University Hospitals Sussex NHS Foundation Trust
2022
Health-related quality of life (HRQL) is a key outcome in stroke clinical trials. Stroke-specific HRQL scales (eg, SS-QOL, SIS) have generally been developed with samples survivors that exclude people aphasia. We adapted the SS-QOL for use aphasia to produce Stroke and Aphasia Quality Life Scale (SAQOL). report results from psychometric evaluation initial 53-item SAQOL item-reduced SAQOL-39.We studied 95 long-term evaluate acceptability, reliability, validity SAQOL-39 using standard...
Study objective: To develop a measure of unplanned pregnancy that is valid, reliable, and appropriate in the context contemporary demographic trends social mores can be used variety situations, including production population prevalence estimates. Design: A two stage study design: qualitative (inductive) methods to delineate construct planning, quantitative/psychometric establish means measurement. Setting: Eight health service providers (comprising 14 clinics, antenatal, abortion, one...
We identified the need to develop a scientifically rigorous measure of health-related quality life (HRQL) in dementia that would be appropriate for use at all stages severity and available both self- proxy-report versions.We used standard psychometric methods eliminate items with poor properties (item-reduction field test) assess acceptability, reliability validity item-reduced instruments (psychometric evaluation test). developed validated two versions DEMQOL: 28-item...
Background Dementia is one of the most common and serious disorders in later life economic personal cost caring for people with dementia immense. There a need to be able evaluate interventions using cost-effectiveness analyses, but generic preference-based measures typically used measure effectiveness do not work well dementia. Existing dementia-specific can effectively health-related quality their current form cannot directly inform analysis quality-adjusted life-years as effectiveness....
Considering the underlying importance of trust, there is too little research into understanding, protection and recovery trust in health care systems, not only for effective functioning systems but also society general. Several researchers have pointed towards a contemporary crisis been many examples that show severe effects mistrust. More public could contribute to improving efficiency while protecting public.
Radical prostatectomy (RP) is an established treatment for localised prostate cancer that can have a significant impact on urinary and sexual function, with recovery over time. Our aim was to describe functional in the first year after RP, reporting descriptive outcomes alongside validated patient-reported outcome measure scores (Expanded Prostate Cancer Index Composite, EPIC-26).
Background: We previously developed the Stroke and Aphasia Quality of Life scale (SAQOL-39) tested it with people chronic aphasia. A allowing comparisons quality life between versus without aphasia post-stroke would be value to clinicians. Objectives: To evaluate psychometrics SAQOL-39 in a generic stroke sample. Should this process result generic-stroke version (SAQOL-39g), further aim is compare latter as Design subjects: Repeated measures psychometric study, evaluating internal...
The Anti-Clot Treatment Scale (ACTS) is a 15-item patient-reported instrument of satisfaction with anticoagulant treatment. It includes 12-item ACTS Burdens scale and 3-item Benefits scale. Its role in clinical trials other settings should be supported by evidence that it both clinically meaningful scientifically sound. aim the study was to evaluate measurement performance (Dutch, Italian, French, German English language versions) patients venous thromboembolism based on traditional...
Abstract Background The evaluation of multi‐dimensional outcomes such as health‐related quality life (HRQL) is particularly relevant in dementia where the disease can compromise all areas functioning. nature make self‐report difficult, yet subjective HRQL makes value proxy reports limited. Previous work suggests that there are domains unique to dementia. We aimed develop a conceptual framework from perspective people with and their carers examine differences these two groups. Methods...
Abstract Background: The finding that exposure to general anesthetics (GAs) in childhood may increase rates of learning disabilities has raised a concern interfere with brain development. generation neuronal circuits, complex process which axons follow guidance cues dendritic targets, is an unexplored potential target for this type toxicity. Methods: GA exposures were conducted developing neocortical neurons culture and early postnatal slices overlaid fluorescently labeled neurons. Axon...
Abstract Background Leptospirosis is a zoonotic bacterial infection occurring worldwide. It of particular public health concern due to its global distribution, epidemic potential and high mortality without appropriate treatment. The method for the management leptospirosis, particularly in severe disease, clouded by methodological inconsistency lack standardized outcome measures. study this protocol details aims develop core set (COS) leptospirosis research. A COS outcomes with international...
PURPOSE With the transition of USMLE Step 1 to Pass/Fail, 2 CK carries added weight in residency selection process. Our goal was develop a predicted score provide students earlier medical school assist with career mentoring. We also sought understand how scores affected student's plans. METHOD Traditional statistical models and machine learning algorithms identify predictors performance were utilized. Predicted provided all Class 2024 at large allopathic school. A cross-sectional survey...
recognition of prevalent delirium and prediction incident may be difficult at first assessment. We therefore aimed to validate a pragmatic susceptibility (for any, delirium) score for use in front-line clinical practice consecutive cohort older acute medicine patients.consecutive patients aged ≥65 years over two 8-week periods (2010-12) were screened prospectively using the Confusion Assessment Method (CAM), was diagnosed DSM IV criteria. The sum weighted risk factors derived pooled data...
Public trust in health systems is pivotal for their effective and efficient functioning. In particular, public essential personal data use, as demonstrated debates many countries, example, about whether from COVID-19 contact tracing apps should be pooled or remain on individuals' smartphones. Low levels of pose a risk not only to system legitimacy but can also harm population health.
Purpose: To develop a conceptual model representing the impact of musculoskeletal impairments (MSIs) in lives children Malawi. Method: A total 169 with MSIs (CMSIs), family and other community members participated 57 interviews, focus groups observations. An inductive approach to data analysis was used conceptualise children's day-to-day lives. Results: The main themes that emerged were Indignity, Exclusion, Pain Hunger. Indignity represents various affronts sense inherent equal worth as...