A5014090847- Chronic Obstructive Pulmonary Disease (COPD) Research
- Respiratory Support and Mechanisms
- Pleural and Pulmonary Diseases
- Tracheal and airway disorders
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Airway Management and Intubation Techniques
- Asthma and respiratory diseases
- Global Public Health Policies and Epidemiology
- Respiratory and Cough-Related Research
- Nosocomial Infections in ICU
- Healthcare Quality and Management
- Infection Control in Healthcare
- Pulmonary Hypertension Research and Treatments
- Obstructive Sleep Apnea Research
- Health Promotion and Cardiovascular Prevention
- Clinical practice guidelines implementation
- Lung Cancer Diagnosis and Treatment
- Primary Care and Health Outcomes
- Nursing Diagnosis and Documentation
- Parkinson's Disease Mechanisms and Treatments
- Delphi Technique in Research
- Thermoregulation and physiological responses
- Research in Social Sciences
- Cardiovascular and Diving-Related Complications
- Smoking Behavior and Cessation
University of Groningen
2019-2024
University Medical Center Groningen
2011-2024
National Patient Safety Foundation
2012-2014
Alberta Health Services
2014
Saskatchewan Health Quality Council
2008
For selected patients with advanced emphysema, bronchoscopic lung volume reduction one-way valves can lead to clinically relevant improvements of airflow obstruction, hyperinflation, exercise capacity, and quality life. The most common complication this procedure is pneumothorax a prevalence up ±34% the treated patients. Patients who develop also experience meaningful clinical benefits once resolved. Timely resolution post-valve treatment requires skilled adequate management. This expert...
Background: Endobronchial valve (EBV) treatment is an effective for patients with severe emphysema. Revision bronchoscopies after endobronchial can be essential to prolong the effect of or address long-term complications. Purpose: To evaluate indications, endoscopic findings and outcomes revision investigate if any predictors granulation tissue formation, EBV treatment, identified. Patients Methods: who underwent between 2016 2019 in our hospital, as routine care, were included. If a patient...
Bronchoscopic lung volume reduction using endobronchial valves (EBV) has been shown to be beneficial for severe emphysema patients. The most important predictor of treatment response is absence collateral ventilation between the target and ipsilateral lobe. However, there are still a substantial number nonresponders it would useful improve pre-treatment identification responders. Presumably, predictors will multifactorial, therefore our aim was explore whether we can identify groups cluster...
Introduction: Currently, there is a lack of bronchoscopic lung volume reduction options that do not depend on fissure integrity. Endobronchial coils have been extensively studied to address this need but exhibited variable patient response and discontinued. Lung tension device (LTD) represent the next-generation coil treatment. This study aimed evaluate safety, feasibility, efficacy LTD-coil Methods: Patients with advanced emphysema hyperinflation were enrolled at two European sites....
<b><i>Background:</i></b> For selected patients with severe emphysema, bronchoscopic lung volume reduction endobronchial valves (EBV) is recognized as an additional treatment option. In most trials investigating EBV treatment, a very low diffusing capacity (DLCO) were excluded from participation. <b><i>Objectives:</i></b> Our goal was to investigate whether in emphysema DLCO safe and effective. <b><i>Methods:</i></b>...
Bronchoscopic lung volume reduction using endobronchial valves (EBV) is a treatment option for selected patients with advanced emphysema. The significantly improves pulmonary function, exercise capacity, quality of life, and potentially survival. Our main aim was to assess whether response influences survival time after EBV treatment.We evaluated at 6-week 1-year follow-up all treated EBVs between 2008 2020. Survival status retrieved on December 1, 2021. Patients were defined as responders...
Bronchoscopic lung volume reduction using one-way endobronchial valves (EBVs) is a valid therapy for severe emphysema patients. However, alpha-1 antitrypsin (AAT)-deficient patients were excluded from the majority of clinical trials investigating this intervention.The aim study was to investigate feasibility, efficacy, and safety EBV treatment in with AAT deficiency (AATD) or reduced level.A retrospective analysis performed all treated confirmed AATD serum level at University Medical Center...
Multiple studies have shown that patients with severe emphysema can significantly benefit from bronchoscopic lung volume reduction endobronchial valve (EBV) treatment up to 1 year after treatment. However, hardly any data exist on longer term follow-up, especially quality of life. Our aim was investigate long-term follow-up EBV 3 years including life in a real-life routine clinical setting.We retrospectively included who underwent our hospital the Netherlands at least prior. Patients were...
<b><i>Background:</i></b> Bronchoscopic lung volume reduction using the Zephyr® endobronchial valve (EBV) is a guideline treatment for patients with advanced emphysema. To achieve reduction, it crucial that there absence of collateral ventilation and complete occlusion target lobe. While 3 EBV sizes (4.0; 4.0-LP; 5.5) are currently available to accommodate all airway sizes, local anatomical variations sometimes warrant wide diameter but shorter length. address this,...
Background Assessment of static hyperinflation severity is crucial to identify COPD patients eligible for lung volume reduction. The current recommendation residual ≥175% predicted may need be reconsidered owing potential differences between the Global Lung Function Initiative (GLI) and European Community Steel Coal (ECSC) reference equations concerns about using percentage predicted. Methods We compared values derived from GLI ECSC mathematically simulated data used a receiver operating...
Bronchoscopic lung volume reduction with endobronchial valves is a guideline treatment leading to improved pulmonary function, exercise tolerance and quality of life, in patients advanced emphysema, severe hyperinflation no collateral ventilation. After valve treatment, loss the initial effect can occur, as well local valve-induced complications such persistent haemoptysis. In these cases, surgical lobectomy be considered achieve similar efficacy outcomes. We evaluated safety feasibility...
Klooster, Karin PhD; Hartman, Jorine E. van Dijk, Marlies MD; Koster, Theodoor David Slebos, Dirk-Jan MD, PhDAuthor Information
Interventions to encourage compliance with smoking control policies often rely on intermediaries for implementation, and the culture of intermediary group might affect policy implementation. The authors present an ethnography security staff involved in enforcing restrictive a large hospital Canada. They find strong norms associated control, mutuality, deference authority. Common sense interpretation rather than strict enforcement rules prevails. To be enforced effectively, would have compete...
Canadian provinces are addressing quality of care and patient safety in a systemic way, but obtaining physician involvement system improvement continues to be challenge. To address this issue, individual physicians, groups, the British Columbia Medical Association, health authorities, BC Patient Safety & Quality Council (BCPSQC) Ministry Health have come together support foster satisfaction. Building on earlier work safety, 2010 ministry developed comprehensive strategy for system-wide...
Abstract Background Bronchoscopic lung volume reduction techniques are minor invasive treatment modalities for severely hyperinflated emphysema patients. The severity of static hyperinflation determines eligibility and success rate these treatments. However, it is not exactly known what parameter should be used to optimally reflect hyperinflation. Commonly parameters residual (RV) the RV/Total capacity (TLC) ratio. Other reflecting Inspiratory Capacity/TLC forced vital capacity. Objectives...
Abstract Background and Purpose In patients with severe emphysema, dynamic hyperinflation is superimposed on top of already existing static hyperinflation. Static reduces significantly after bronchoscopic lung volume reduction (BLVR). this study, we investigated the effect BLVR compared to standard care (SoC) Methods Dynamic was induced by a manually paced tachypnea test (MPT) defined change in inspiratory capacity (IC) measured before MPT. measurements were performed both at baseline 6...