A5060332012- Esophageal Cancer Research and Treatment
- Gastric Cancer Management and Outcomes
- Esophageal and GI Pathology
- Enhanced Recovery After Surgery
- Lung Cancer Diagnosis and Treatment
- Colorectal Cancer Surgical Treatments
- Pancreatic and Hepatic Oncology Research
- Cardiac, Anesthesia and Surgical Outcomes
- Bariatric Surgery and Outcomes
- Nutrition and Health in Aging
- Appendicitis Diagnosis and Management
- Gastrointestinal Tumor Research and Treatment
- Intraperitoneal and Appendiceal Malignancies
- Hernia repair and management
- COVID-19 and healthcare impacts
- Body Contouring and Surgery
- Tracheal and airway disorders
- Lung Cancer Treatments and Mutations
- Metastasis and carcinoma case studies
- Genetic factors in colorectal cancer
- Immune cells in cancer
- Global Health and Surgery
- Cancer, Lipids, and Metabolism
- Head and Neck Cancer Studies
- Extracellular vesicles in disease
McGill University Health Centre
2021-2024
McGill University
2022-2024
Montreal General Hospital
2021-2024
Shaare Zedek Medical Center
2017-2024
University of British Columbia
2024
Hebrew University of Jerusalem
2019-2023
University of Edinburgh
2022
St Mary's Hospital
2019-2021
St. Mary's Hospital
2019-2021
Imperial College Healthcare NHS Trust
2019-2021
Lymph nodes (LNs) are frequently the first sites of metastasis. Currently, only prognostic LN assessment is determining metastatic status. However, there evidence suggesting that metastasis facilitated by formation a pre-metastatic niche induced tumour derived extracellular vehicles (EVs). Therefore, it important to detect and modify environmental changes. Earlier work has demonstrated neutrophil traps (NETs) can sequester promote distant Here, we confirmed NETs associated with reduced...
Abstract Early events associated with chronic inflammation and cancer involve significant remodeling of the extracellular matrix (ECM), which greatly affects its composition functional properties. Using lung squamous cell carcinoma (LSCC), a inflammation‐associated (CIAC), we optimized robust proteomic pipeline to discover potential biomarker signatures protein changes specifically in stroma. We combined ECM enrichment from fresh human tissues, data‐independent acquisition (DIA) strategies,...
Abstract Purpose Advanced imaging may augment the diagnostic milieux for presumed acute appendicitis (AA) during pregnancy, however it is not clear when such modalities are indicated. The aim of this study was to assess sensitivity and specificity clinical scoring systems with findings on magnetic resonance (MRI) AA in pregnant patients. Methods A retrospective cohort between 2019 2021 performed two tertiary level centers. Pregnant patients presenting suspected non-diagnostic trans-abdominal...
The safety and efficacy of enhanced recovery after surgery (ERAS) following elective gastrectomy for gastric cancer in patients >80 years age are not well described. aim this study was to explore whether an ERAS protocol group can be safely implemented reduce postoperative length stay.
During coronavirus disease 2019 (COVID-19)-related operating room closures, some multidisciplinary thoracic oncology teams adopted a paradigm of stereotactic ablative radiotherapy (SABR) as bridge to surgery, an approach called SABR-BRIDGE. This study presents the preliminary surgical and pathological results.Eligible participants from four institutions (three in Canada one United States) had early-stage presumed or biopsy-proven lung malignancy that would normally be surgically resected....
The treatment paradigm for patients with stage II/III non-small-cell lung cancer (NSCLC) is rapidly evolving. We performed a modified Delphi process culminating at the Early-stage Lung International eXpert Retreat (ELIXR23) meeting held in Montreal, Canada, June 2023. Participants included medical and radiation oncologists, thoracic surgeons pathologists from across Quebec. Statements relating to diagnosis paradigms preoperative, operative postoperative time periods were generated until all...
The impact on pregnancy of laparoscopy for acute appendicitis is well documented. However, with an accurate pre-operative diagnosis being more challenging in pregnant patients, the incidence a negative appendectomy (NA) higher this cohort. aim study was to evaluate maternal and neonatal implications NA during pregnancy.A single center retrospective between 2004 2019 performed. Pregnant women who underwent laparoscopic suspected were identified from which those had pathologically normal...
Physiotherapy is a major cornerstone of enhanced rehabilitation after surgery (ERAS) and reduces the development atelectasis thoracic surgery. By initiating physiotherapy in post-anaesthesia care unit (PACU), aim was to evaluate whether ultra-early initiation (in first hour following tracheal extubation) would improve outcomes patients undergoing elective