Brandon V. Duffy

ORCID: 0000-0002-2049-2781
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About
Contact & Profiles
Research Areas
  • Retinal Diseases and Treatments
  • Glaucoma and retinal disorders
  • Retinal Imaging and Analysis
  • Immune Response and Inflammation
  • Retinal and Optic Conditions
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Retinal and Macular Surgery
  • Intraocular Surgery and Lenses

Northwestern University
2023-2024

Harvard College Observatory
2020

Massachusetts Eye and Ear Infirmary
2020

Harvard University
2020

Smith-Kettlewell Eye Research Institute
2020

Abstract Proliferative vitreoretinopathy (PVR) is the leading cause of retinal detachment surgery failure. Despite significant advances in vitreoretinal surgery, it still remains without an effective prophylactic or therapeutic medical treatment. After ocular injury detachment, misplaced cells undergo epithelial to mesenchymal transition (EMT) form contractile membranes within eye. We identified Runt-related transcription factor 1 (RUNX1) as a gene highly expressed surgically-removed human...

10.1038/s41598-020-77254-0 article EN cc-by Scientific Reports 2020-11-30

Acute orbital inflammation can lead to irreversible vision loss in serious cases. Treatment thus far has been limited systemic steroids or surgical decompression of the orbit. An animal model that mimics characteristic features acute as found thyroid eye disease be used explore novel treatment modalities.We developed a murine by injecting oxazolone into mouse The mice underwent magnetic resonance imaging (MRI) and were euthanized at various time points for histologic examination....

10.1167/tvst.9.8.26 article EN cc-by-nc-nd Translational Vision Science & Technology 2020-07-16

To evaluate the reliability of clinical grading diabetic retinopathy (DR) severity compared with on ultra-widefield pseudocolor fundus (UWF-CF) and fluorescein angiography (UWF-FA) images their relative detection sight-threatening DR referable DR.

10.1097/iae.0000000000004140 article EN Retina 2024-04-26
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