A5018985949- Retinal and Macular Surgery
- Retinal Diseases and Treatments
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Retinal and Optic Conditions
- Neurological Complications and Syndromes
- Glaucoma and retinal disorders
- Immune Response and Inflammation
- Phagocytosis and Immune Regulation
- Public Administration and Political Analysis
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Intraocular Surgery and Lenses
- Chronic Obstructive Pulmonary Disease (COPD) Research
- SARS-CoV-2 and COVID-19 Research
Massachusetts Eye and Ear Infirmary
2019-2021
Harvard University
2020-2021
Smith-Kettlewell Eye Research Institute
2019-2021
Harvard College Observatory
2020
Abstract Proliferative vitreoretinopathy (PVR) is the leading cause of retinal detachment surgery failure. Despite significant advances in vitreoretinal surgery, it still remains without an effective prophylactic or therapeutic medical treatment. After ocular injury detachment, misplaced cells undergo epithelial to mesenchymal transition (EMT) form contractile membranes within eye. We identified Runt-related transcription factor 1 (RUNX1) as a gene highly expressed surgically-removed human...
Acute orbital inflammation can lead to irreversible vision loss in serious cases. Treatment thus far has been limited systemic steroids or surgical decompression of the orbit. An animal model that mimics characteristic features acute as found thyroid eye disease be used explore novel treatment modalities.We developed a murine by injecting oxazolone into mouse The mice underwent magnetic resonance imaging (MRI) and were euthanized at various time points for histologic examination....