A5015041050- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Bone and Joint Diseases
- Pelvic and Acetabular Injuries
- Metal-Organic Frameworks: Synthesis and Applications
- Advanced Sensor and Energy Harvesting Materials
- Organometallic Compounds Synthesis and Characterization
- Orthopedic Infections and Treatments
- Periodontal Regeneration and Treatments
- Spinal Hematomas and Complications
- Nanoplatforms for cancer theranostics
- Surface Modification and Superhydrophobicity
- Cervical and Thoracic Myelopathy
- Gastric Cancer Management and Outcomes
- Medical Imaging and Analysis
- Photoacoustic and Ultrasonic Imaging
- Cerebral Venous Sinus Thrombosis
- Membrane Separation Technologies
- Cancer Treatment and Pharmacology
- Infectious Diseases and Tuberculosis
- Endometrial and Cervical Cancer Treatments
- Sarcoidosis and Beryllium Toxicity Research
- Breast Cancer Treatment Studies
- Vitamin D Research Studies
- Cancer Diagnosis and Treatment
Affiliated Zhongshan Hospital of Dalian University
2011-2024
Liaocheng University
2020-2022
Beijing Hospital
2021-2022
Anhui Medical University
2021
Second Hospital of Anhui Medical University
2021
Xian Yang Central Hospital
2021
Dalian University of Technology
2020
Karamay Central Hospital
2019
Xinjiang Medical University
2019
Beijing HuiLongGuan Hospital
2012
The influence of the vitamin D receptor (VDR) gene for risk osteoporosis remains to be elucidated. aim present study was understand distribution various single-nucleotide polymorphisms (SNPs) within VDR and its association with osteoporosis. In total, 378 subjects without a genetic relationship were recruited between January 2013 July 2015. divided into three groups, which normal (n=234), (n=65) osteoporotic fracture (n=79) groups. Three pertinent SNPs rs17879735 (ApaI, Allele A/a, SNP C>A)...
Abstract Background Steroid-induced osteonecrosis of the femoral head (SONFH) is a devastating orthopedic disease, which seriously affects quality life patients. The study aims to investigate effects LncRNA NORAD on SONFH. Methods Human bone marrow-derived mesenchymal stem cells (hBMSCs) were isolated from proximal femur patients during routine surgery and then cultured with dexamethasone (Dex) transfected overexpression vector, siRNA-NORAD miR-26a-5p mimics. mRNA expression NORAD,...
Abstract Background Long-term use of steroid may lead to osteonecrosis the femoral head (ONFH). Mechanical stress help bone formation and remodeling. This study aimed probe role mechanical in recovery rats. Methods Rat models with ONFH were induced by steroid. Rats subjected different levels (weight-bearing training), then morphology density rats measured. The mRNA protein OPG/RANK/RANKL axis rat assessed. Gain- loss-of function experiments OPG performed identify its following implement. ex...
OBJECTIVE: To evaluate the biomechanical effects of internal fixation with different screw insertion depths on vertebrae stiffness and stress for L1 fracture. METHODS: The established fracture was fixed 10 inse
Non-invasive removal of thrombosis is a difficult problem in clinical vascular disease. Herein, we reported magnetic hyperthermia combined photothermal therapy for celiac vein using Fe3S4 nanoparticles as thrombolytic agents under the stimulation near infrared (NIR) laser and an external alternating field (AMF). showed excellent magnetothermal conversion performance continuous AMF very good irradiation NIR laser. Moreover, exhibited synergistic thermal effect co-stimulation AMF. In addition,...
Massive hemorrhage caused by the uncontrolled release of thrombolysis drugs is a key issue therapy in clinical practice. In this study, we report near-infrared (NIR) light-triggered drug delivery system, i.e., CuS@mSiO 2 -PEG (CSP) nanoparticles, for loading thrombolytic (urokinase plasminogen activators, uPA). CSP nanoparticles with CuS as photothermal agents and mesoporous SiO uPA were synthesized using facile hydrothermal method. The core-shell demonstrated to possess excellent...
Objective This study was performed to investigate the effect of microscopically assisted decompression using a micro-hook scalpel on ossification posterior longitudinal ligament (OPLL). Methods Sixty-one patients with OPLL were divided into Group A (posterior surgery laminectomy responsible segment and lateral mass screw fixation) B (anterior cervical corpectomy intervertebral titanium cage fusion). Neurological function assessed by Japanese Orthopaedic Association (JOA) score, visual analog...
Objective To discuss the surgical outcome of fenestration assistant by microscopy for single-level lumbar disc protrusion (LDH), compared with tradition laminotomy and discectomy. Methods From January 2008 to 2010, forty-eight patients underwent traditional open discectomy 40 surgery. The involved L3- L4 level in 12 cases, L4-L5 46 L5-S1 30 cases; preoperative JOA score was 8-19 points (average 12.9 points) 7-19 12.7 surgery patients. Results Cauda equina injury occurred repaired 2 cases...
Objective To evaluate the characteristics and efficacy of microscope-assisted bilateral decompression via unilateral approach for treatment lumbar stenosis. Methods From June 2007 to 2010, Sixty case stenosis with were treated under microscopy. Patients followed up from 6 24 months, average (12 ± 4.7) months. Results The pain level each patient was assessed both before after opeartion, using a visual analogue scale (VAS). Intermittent claudication completely relieved in 57 out 60 cases,...
Objective To comparison anterior cervical decompression and plating techniques for CSM between under microscope traditional method retrospectively, investigate clinical result of surgery microscope. Methods Sixty-seven patients with underwent were evaluated retrospectively from January 2008 to June 2010. Thirty-three operation microscope; thirty-four operation. The operating time, bleeding volume during poster operating, walking time post-operation complication observed. Clinical outcomes...
Objective To study the expression of CD133 protein in gastric cancer tissue and its relationship with infection helicobacter pylori(HP).Methods The levels were detected by immunohistochemistry 62 cases surgically removed 41 corresponding non-tumor normal tissues.The status HP was upgrade Giemsa staining tissues 103 cases.The between analyzed.Results rates positive for 48.4％ (30/62) carcinoma tissue,and 26.8％ (11/41) tissues,there significant difference (P =0.023).The rate 65.8％ (50/76)...
Objective To analyze the correlation between prognosis and changes of PT, APTT D-dimer before after operation in patients with colon carcinoma. Methods Between January 2011 2015, one hundred twenty carcinoma were chosen as study objects, level detected 1 day operation, 2 days variations recorded analyzed combined pathological characteristics complication rate. Results The variation PT was (1.1±0.4) s, that (5.4±2.4) (112.5±31.4) μg/L. After hemorrhage occurred 9 (7.5%), 12...
Objective To explore efficacy of breast-conserving surgery (BCS) combined with endoscopic axillary lymph node dissection (EALND) in the treatment early breast cancer. Methods A total 60 patients cancer Department General Surgery, Karamay Central Hospital from July 2009 to 2011 were enrolled for a prospective study. The divided into three groups according their wishes: BCS+ EALND group (16 cases), BCS (20 cases) and modified radical mastectomy (MRM) (24 cases). χ2 test Fisher exact was...