A5085683956- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Transplantation: Methods and Outcomes
- Cardiac Arrest and Resuscitation
- Cardiac Valve Diseases and Treatments
- Cardiac and Coronary Surgery Techniques
- Heart Failure Treatment and Management
- Cardiac pacing and defibrillation studies
- Organ Transplantation Techniques and Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- Fuel Cells and Related Materials
- Cardiac tumors and thrombi
- Cardiac Arrhythmias and Treatments
- Cardiac Ischemia and Reperfusion
- Renal Transplantation Outcomes and Treatments
- Congenital Heart Disease Studies
- Aortic Disease and Treatment Approaches
- Atrial Fibrillation Management and Outcomes
- Infective Endocarditis Diagnosis and Management
- Acute Kidney Injury Research
- Intensive Care Unit Cognitive Disorders
- Cancer-related molecular mechanisms research
- Advanced MRI Techniques and Applications
- Long-Term Effects of COVID-19
- Organ and Tissue Transplantation Research
Baylor College of Medicine
2019-2025
St. Luke's Hospital
2024
University of Minnesota
2009-2019
University of Minnesota Medical Center
2008-2016
Minnesota Department of Health
2016
Minneapolis Institute of Arts
2016
Nanjing Medical University
2014
University of Minnesota System
2012
Hy-Line (United States)
2009
Medtronic (United States)
2006
Background— Induced pluripotent stem cells (iPSCs) can be differentiated into potentially unlimited lineages of cell types for use in autologous therapy. However, the efficiency differentiation procedure and subsequent function iPSC-derived may influenced by epigenetic factors that iPSCs retain from their tissues origin; thus, more effective treatment myocardial injury if were engineered cardiac-lineage cells, rather than dermal fibroblasts. Methods Results— We show human cardiac (hciPSCs)...
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), a novel coronavirus responsible for worldwide pandemic has forced drastic changes in medical practice an alarmingly short period of time. Caregivers must modify their strategies as well optimize the utilization resources to ensure public and patient safety. For organ transplantation, particular, loss lifesaving organs transplantation could lead increased waitlist mortality. The priority is select uninfected donors transplant...
First-month renal function trajectories after left ventricular assist device (LVAD) implantation vary widely. Lack of improvement (RFI) and postoperative acute kidney injury (AKI) are associated with increased mortality. This study evaluates plasma levels endostatin cystatin C as predictors RFI AKI 1 month post-LVAD implantation. We prospectively enrolled 52 advanced heart failure patients undergoing LVAD Blood samples were collected pre-implant at 1, 2, 3, 4 weeks post-implant. Plasma...
We investigated ferroptosis, a type of programmed cell death mechanism, in human hearts donated after brain (DBD) and those circulatory (DCD), focusing on warm ischemia time (WIT) cold storage. A total twenty-four were procured, with six from the DBD group eighteen DCD group. The was divided into three subgroups, each containing hearts, based different WITs 20, 40, 60 minutes. All procured placed storage for up to 6 hours. Left ventricular biopsies performed at 0, 2, 4, measured ferroptosis...
Delirium is a common neurological complication in patients with advanced heart failure (ADHF) following left ventricular assist device (LVAD) implantation, significantly impacting recovery. This study aimed to analyze non-contrast computed tomography (CT) scans of the brain ADHF undergoing LVAD implantation determine association between pre-existing atrophy and postoperative delirium. A involving 166 was conducted from March 2020 July 2023. Non-contrast CT were analyzed using quantitative...
Abstract This report reviews 5 cases of mitral annular caseoma. Four patients presented with fatigue, stroke, or stenosis. Robot-assisted resection caseoma without valve replacement was successfully performed in all good outcomes. These demonstrate the safety and efficacy robotic surgery treating
Catheter ablation of hemodynamically unstable ventricular tachycardia (VT) is possible with mechanical circulatory support (MCS), little known regarding the relative safety and efficacy different supporting devices for such procedures.Sixteen consecutive patients (aged 63 ± 11 years left ejection fraction 20 9%) who underwent VT were included in this study. Hemodynamic percutaneous (Impella® 2.5, n = 5) implantable assist (LVADs, 6) peripheral cardiopulmonary bypass (CPB, 5). Except 2...
Vasoplegia after cardiac surgery is associated with adverse outcomes. However, the clinical effects of vasoplegia and significance its duration continuous-flow left ventricular assist device (CF-LVAD) implantation are less known. This study aimed to identify predictors outcomes from transient vs prolonged CF-LVAD implantation. The was a retrospective review consecutive patients who underwent between January 1, 2005, December 31, 2017. defined as presence all following: mean arterial pressure...
We explored whether women undergo continuous-flow left ventricular assist device (CF-LVAD) implantation in later stages of heart failure (HF) than men, evidenced by worse preoperative right HF (RHF). also compared two propensity models with and without RHF to assess its effect on outcomes. INTERMACS was queried from July 2008 December 2017. Propensity model 1 matched men age ≥50 years, etiology, body surface area, class, comorbidities, strategy, temporary mechanical circulatory support,...