A5101450089- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Cardiac Arrest and Resuscitation
- Respiratory Support and Mechanisms
- Sepsis Diagnosis and Treatment
- Heart Failure Treatment and Management
- Intensive Care Unit Cognitive Disorders
- Higher Education Learning Practices
- Transplantation: Methods and Outcomes
- Hemodynamic Monitoring and Therapy
- Cardiac pacing and defibrillation studies
- Student Assessment and Feedback
- Education Systems and Policy
- Ultrasound in Clinical Applications
- Evaluation and Performance Assessment
- Neonatal Respiratory Health Research
- Forecasting Techniques and Applications
- Inflammasome and immune disorders
- Family and Patient Care in Intensive Care Units
- Psychometric Methodologies and Testing
- Engineering Education and Curriculum Development
- Global Educational Policies and Reforms
- Complex Systems and Decision Making
- Lexicography and Language Studies
- Music Technology and Sound Studies
Queen's University Belfast
2014-2025
Royal Victoria Hospital
2015-2025
University of Ulster
2015-2025
Belfast Health and Social Care Trust
2021-2025
Royal Victoria Eye and Ear Hospital
2017-2024
John Hunter Hospital
2023-2024
Hunter New England Local Health District
2024
International Society for Heart and Lung Transplantation
2024
IFC Research (United Kingdom)
2024
University of Newcastle Australia
2022-2023
The use of left ventricular assist devices is an accepted therapy for patients with refractory heart failure, but current pulsatile volume-displacement have limitations (including large pump size and limited long-term mechanical durability) that reduced widespread adoption this technology. Continuous-flow pumps are newer types developed to overcome some these limitations.In a prospective, multicenter study without concurrent control group, 133 end-stage failure who were on waiting list...
The Faculty of Intensive Care Medicine and Society Guideline Development Group have used GRADE methodology to make the following recommendations for management adult patients with acute respiratory distress syndrome (ARDS). British Thoracic supports in this guideline. Where mechanical ventilation is required, use low tidal volumes (<6 ml/kg ideal body weight) airway pressures (plateau pressure <30 cmH
Data for left ventricular assist devices (LVADs) in patients with noninotrope-dependent heart failure (HF) are limited. The goal of this study was to evaluate HeartMate II (HMII) LVAD support versus optimal medical management (OMM) ambulatory New York Heart Association functional class IIIB/IV meeting indications destination therapy but not dependent on intravenous inotropic support. This a prospective, multicenter (N = 41), observational 200 (97 LVAD, 103 OMM). Entry criteria included ≥1...
The HeartMate 3 (HM3) Left Ventricular Assist System (LVAS) (Abbott) is a centrifugal, fully magnetically levitated, continuous-flow blood pump engineered to enhance hemocompatibility and reduce shear stress on components. MOMENTUM trial (Multicenter Study of MagLev Technology in Patients Undergoing Mechanical Circulatory Support Therapy With 3) compares the HM3 LVAS with II (HMII) advanced heart failure refractory medical management, irrespective therapeutic intention (bridge transplant...
The authors sought to provide the pre-specified primary endpoint of ROADMAP (Risk Assessment and Comparative Effectiveness Left Ventricular Assist Device Medical Management in Ambulatory Heart Failure Patients) trial at 2 years.The was a prospective nonrandomized observational study 200 patients (97 with left ventricular assist device [LVAD], 103 on optimal medical management [OMM]) that showed survival improved functional status 1 year better LVADs compared OMM patient population ambulatory...
<h3>Importance</h3> In patients who require mechanical ventilation for acute hypoxemic respiratory failure, further reduction in tidal volumes, compared with conventional low volume ventilation, may improve outcomes. <h3>Objective</h3> To determine whether lower using extracorporeal carbon dioxide removal improves outcomes failure. <h3>Design, Setting, and Participants</h3> This multicenter, randomized, allocation-concealed, open-label, pragmatic clinical trial enrolled 412 adult receiving...
Background— The effects of continuous blood flow and reduced pulsatility on major organ function have not been studied in detail. Methods Results— We evaluated renal (creatinine urea nitrogen) hepatic (aspartate transaminase, alanine total bilirubin) 309 (235 male, 74 female) advanced heart failure patients who had supported with the HeartMate II continuous-flow left ventricular assist device for bridge to transplantation. To determine whether impaired improve over time support or there are...