A5038054381- Intensive Care Unit Cognitive Disorders
- Respiratory Support and Mechanisms
- Family and Patient Care in Intensive Care Units
- Long-Term Effects of COVID-19
- Frailty in Older Adults
- Hip and Femur Fractures
- Sepsis Diagnosis and Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Delphi Technique in Research
- Nutrition and Health in Aging
- Nosocomial Infections in ICU
- Airway Management and Intubation Techniques
- Clinical Nutrition and Gastroenterology
- Cardiac Arrest and Resuscitation
- Palliative Care and End-of-Life Issues
- Pediatric Pain Management Techniques
- COVID-19 Clinical Research Studies
- Cerebral Palsy and Movement Disorders
- Bone and Joint Diseases
- COVID-19 and Mental Health
- Neonatal Respiratory Health Research
- Patient Satisfaction in Healthcare
- Traumatic Brain Injury and Neurovascular Disturbances
- Pneumonia and Respiratory Infections
Queen's University Belfast
2019-2024
St Thomas' Hospital
2013-2024
Guy's and St Thomas' NHS Foundation Trust
2015-2024
University of Oxford
2023-2024
The University of Melbourne
2017-2024
King's College London
2015-2024
Belfast Health and Social Care Trust
2024
Collaborative Group (United States)
2023
University College London
2010-2023
National Institute for Health Research
2017-2023
Survivors of critical illness demonstrate skeletal muscle wasting with associated functional impairment.To perform a comprehensive prospective characterization wasting, defining the pathogenic roles altered protein synthesis and breakdown.Sixty-three critically ill patients (59% male; mean age: 54.7 years [95% CI, 50.0-59.6 years]) an Acute Physiology Chronic Health Evaluation II score 23.5 (95% 21.9-25.2) were prospectively recruited within 24 hours following intensive care unit (ICU)...
The Faculty of Intensive Care Medicine and Society Guideline Development Group have used GRADE methodology to make the following recommendations for management adult patients with acute respiratory distress syndrome (ARDS). British Thoracic supports in this guideline. Where mechanical ventilation is required, use low tidal volumes (<6 ml/kg ideal body weight) airway pressures (plateau pressure <30 cmH
Quadriceps weakness is an important complication of advanced chronic obstructive pulmonary disease (COPD) but few data exist concerning muscle bulk in early disease. We hypothesised that quadriceps bulk, measured by ultrasound rectus femoris cross-sectional area (USRF CSA ), would be reduced mild, as well advanced, COPD compared with controls, and correlate physical activity. 161 patients stable 40 healthy subjects had a measurement USRF wore multisensor armband to record was Global...
<h3>Importance</h3> Continuous positive airway pressure (CPAP) and high-flow nasal oxygen (HFNO) have been recommended for acute hypoxemic respiratory failure in patients with COVID-19. Uncertainty exists regarding the effectiveness safety of these noninvasive strategies. <h3>Objective</h3> To determine whether either CPAP or HFNO, compared conventional therapy, improves clinical outcomes hospitalized COVID-19–related failure. <h3>Design, Setting, Participants</h3> A parallel group,...
Puthucheary, Zudin A.; Rawal, Jaikitry; Mcphail, Mark; Connolly, Bronwen; Ratnayake, Gamunu; Chan, Pearl; Hopkinson, Nicholas S.; Padhke, Rahul; Dew, Tracy; Sidhu, Paul Velloso, Cristiana; Seymour, John; Agley, Chibeza C.; Selby, Anna; Limb, Marie; Edwards, Lindsay M.; Smith, Kenneth; Rowlerson, Anthea; Rennie, Michael Moxham, Harridge, Stephen D. R.; Hart, Nicholas; Montgomery, Hugh E. Author Information
Section:ChooseTop of pageAbstract <<Need for Precise and Accu...Measuring Up: Methods for...Current State the Tran...Challenges in Critical Ca...Perspectives: Optimizing ...ReferencesCITING ARTICLES
Abstract Introduction Impaired skeletal muscle function has important clinical outcome implications for survivors of critical illness. Previous studies employing volitional manual testing diagnosing intensive care unit-acquired weakness (ICU-AW) during the early stages illness have only provided limited data on outcome. This study aimed to determine inter-observer agreement and predictive value Medical Research Council sum score (MRC-SS) test in critically ill patients. Methods Study 1:...
Supported by the U.K. National Institute of Health Research (NIHR) (Z.A.P.), Batchworth Charitable Trust, Moulton Foundation, and NIHR University College London Hospitals Biomedical Centre (UCLH BRC) (A.S.M.), Councils UK (S.D.H.), Clinical Facility BRC at Guy’s St. Thomas’ Service (NHS) Foundation Trust (GSST) King’s (N.H. B.C.), UCLH (H.E.M., Z.A.P., A.S.M.). The doctorate fellowship (2010–2014) underpinned core patient population study on which this follow-up was built, as did funding...
The study objective was to obtain consensus on physical therapy (PT) in the rehabilitation of critical illness survivors after hospital discharge. Research questions were: what are PT goals, recommended measurement tools, and constitutes an optimal intervention for illness? A Delphi conducted. Panelists were included based relevant fields expertise, years clinical experience, publication record. literature review determined five themes, forming basis round one, which aimed at generating...
Objective To comprehensively update and survey the current provision of recovery, rehabilitation follow-up services for adult critical care patients across UK. Design Cross-sectional, self-administered, predominantly closed-question, electronic, online survey. Setting Institutions providing identified from national databases. Participants Multiprofessional clinicians delivering at each site. Results Responses 176 UK hospital sites were included (176/242, 72.7%). Inpatient recovery present...
Objective To determine the implementation of National Institute for Health and Care Excellence guidance (NICE CG83) posthospital discharge critical illness follow-up rehabilitation programmes. Design Closed-question postal survey. Setting Adult intensive care units (ICUs) across UK, identified from national databases organisations. Specialist-only private ICUs were not included. Participants Senior respiratory physiotherapy clinicians. Results A representative sample 182 surveys was returned...
Our objective was to obtain international consensus on a set of core outcome measures that should be recorded in all clinical trials interventions intended modify the duration ventilation for invasively mechanically ventilated patients ICU.A two-stage process undertaken between December 2015 and January 2018. Stage 1 included an online three-round Delphi study three meetings. 2 meetings.The setting international, including Europe, North South America, Australia, Asia, Africa.Organization...