A5044853751- COVID-19 Clinical Research Studies
- Palliative Care and End-of-Life Issues
- Long-Term Effects of COVID-19
- Intensive Care Unit Cognitive Disorders
- SARS-CoV-2 and COVID-19 Research
- Childhood Cancer Survivors' Quality of Life
- Patient Dignity and Privacy
- Respiratory Support and Mechanisms
- Mindfulness and Compassion Interventions
- Dialysis and Renal Disease Management
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Cardiac Arrest and Resuscitation
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Healthcare innovation and challenges
- Adolescent and Pediatric Healthcare
- COVID-19 and Mental Health
- Vasculitis and related conditions
- Organ Donation and Transplantation
- Family and Patient Care in Intensive Care Units
- SARS-CoV-2 detection and testing
- Heparin-Induced Thrombocytopenia and Thrombosis
- Microscopic Colitis
- Thermal Regulation in Medicine
- Sarcoidosis and Beryllium Toxicity Research
- Trauma Management and Diagnosis
Leeds Beckett University
2025
Pennine Acute Hospitals NHS Trust
2015-2024
The Recovery Center
2022
University of Lincoln
2021
King's College Hospital
2018-2020
Royal Blackburn Teaching Hospital
2016
King's College Hospital NHS Foundation Trust
2009-2015
King's College London
2013
Peninsula Health
2013
Essex Cardiothoracic Centre
2009
<h3>Importance</h3> Continuous positive airway pressure (CPAP) and high-flow nasal oxygen (HFNO) have been recommended for acute hypoxemic respiratory failure in patients with COVID-19. Uncertainty exists regarding the effectiveness safety of these noninvasive strategies. <h3>Objective</h3> To determine whether either CPAP or HFNO, compared conventional therapy, improves clinical outcomes hospitalized COVID-19–related failure. <h3>Design, Setting, Participants</h3> A parallel group,...
Background: There is a need to improve end-of-life care for people with end-stage kidney disease, particularly due the increasingly elderly, frail and co-morbid disease population. Timely, sensitive individualised Advance Care Planning discussions are acceptable beneficial can help foster realistic hopes goals. Aim: To explore experiences of regarding starting haemodialysis, its impact on quality life their preferences future needs this population timing support. Study design:...
Background: Most studies of the rapid response team (RRT) investigate effect introducing an RRT on outcomes all hospitalised patients. Less information exists patient epidemiology, or changes in call numbers with time.Objectives: To estimate inhospital mortality patients subject to review, proportion deaths reviewed by RRT, and annual time.Method: Retrospective observational study adult RRTequipped Australian hospitals for up 10 years (2000–2009).Participants outcome measures: Thirty-four...
Background: In recent years, the End-Stage Kidney Disease population has increased and is ever more frail, elderly co-morbid. A care-focused approach needs to be incorporated alongside disease focus, identify those who are deteriorating improve communication about preferences future care. Yet many renal professionals feel unprepared for such discussions. Aim: To develop pilot a REnal specific Advanced Communication Training (REACT) programme address of patients professionals. Design:...
UK policymakers, clinicians and public wish to see improvements in end-of-life care (EoLC). However, healthcare professionals' skills knowledge deliver high-quality are often lacking. Since May 2012, palliative staff an inner-city tertiary hospital have run a 2-day Transforming End of Life Care (TEoLC) course improve EoLC confidence, competence among community staff.To evaluate participants' self-rated topics.A before-and-after design using self-completion questionnaires, precourse...
The prevalence of pulmonary manifestations ANCA-associated vasculitis (AAV) is not well understood. This study describes the respiratory complications AAV detected via imaging in patients presenting to a secondary renal centre and associations with mortality.105 were identified from Chronic Renal Insufficiency Standards Implementation Study (CRISIS). CRISIS prospective epidemiological chronic kidney disease stages 3-5, both who did require dialysis on presentation. Patients recruited between...
Background and aims It has been reported that occult gastrointestinal bleeding as detected by faecal blood (FOB) testing can occur in coeliac disease. This study examines whether a positive FOB is feature of disease FOB-positive subjects need investigation for Methods First, the records patients on Nottingham Register Coeliac Disease were reviewed testing. Second, colorectal cancer screening trial database was also to examine how many had participated their results. Finally, sera from 309...
Kate Shepherd, Sarah Watson and Emma Murphy discuss the development of specialist renal palliative care roles, aims conservative pathways for patients with chronic kidney disease who do not wish to pursue replacement therapy.
<h3>Introduction</h3> Referral rates to Specialist Palliative Care are low in Idiopathic Pulmonary Fibrosis (IPF) despite mean survival of 3 years,<sup>1</sup> and a high symptom burden the final year, particular dyspnoea, chest pain, anxiety depression, fatigue.<sup>2</sup> This study aimed explore clinicians' experiences delivering care advanced IPF. <h3>Methods</h3> Questionnaires were distributed at regional Respiratory meeting, focussing on initiating End-of-Life discussions, predicting...
Abstract The misuse of substances is often maintained by both physical and psychological factors. Opioid-substitution medications manage aspects addiction; however, difficulties with emotional regulation avoidance perpetuate continued substance misuse. In the UK, individuals who are excluded from mental health services, meaning these underlying not addressed. Acceptance Commitment Therapy (ACT) seeks to reduce avoidance. A hermeneutic single-case efficacy design was used evaluate effects ACT...
Background Respecting Patient Choices (RPC) model of ACP has been established in Australia for 10 years. Peninsula Health 35 residential aged care facilities (RACF) its catchment area, yet few residents present to acute with an ACP. Aim To assess the current levels implementation including degree variation from RPC evidence-based practice sector. Methods 30 participating RACFs underwent a comprehensive survey conducted via interview and random 10% sample health record audit collect data....
Abstract Introduction: EMT is frequently activated in a subset of tumor cells during disease progression. described as downregulation E-cadherin with corresponding upregulation mesenchymal markers such Vimentin. linked to carcinoma progression stemming from increased cell motility, growth, survival, and invasion. The c-Met receptor MACC1 (metastasis-associated colon cancer-1) are often upregulated CRC metastases, have been associated metastasis, represent potential drug targets. Here we...