- Reproductive Biology and Fertility
- Total Knee Arthroplasty Outcomes
- Telemedicine and Telehealth Implementation
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Mobile Health and mHealth Applications
- Ovarian function and disorders
- Liver Disease Diagnosis and Treatment
- Cytomegalovirus and herpesvirus research
- Gynecological conditions and treatments
- MicroRNA in disease regulation
- Stroke Rehabilitation and Recovery
- Cancer therapeutics and mechanisms
- Phytoestrogen effects and research
- Viral gastroenteritis research and epidemiology
- Dysphagia Assessment and Management
- Acute Ischemic Stroke Management
- Glycosylation and Glycoproteins Research
- Proteins in Food Systems
- Cancer survivorship and care
- Prenatal Screening and Diagnostics
- Palliative Care and End-of-Life Issues
- Infant Nutrition and Health
- Natural Compounds in Disease Treatment
- Cancer-related molecular mechanisms research
Shanghai University of Medicine and Health Sciences
2020-2025
Yangzhou University
2024
University of Newcastle Australia
2020-2024
Northwest University
2021-2024
Xuzhou Medical College
2024
Fujian Medical University
2018-2024
Soochow University
2024
First Affiliated Hospital of Soochow University
2024
Shandong University
2024
Shihezi University
2020-2023
Sulfated polysaccharide from sea cucumber (SCSP), fucoidan brown algae, and iota-carrageenan red algae show inhibitory activities against SARS-CoV-2.
The COVID-19 has emerged as an epidemic, causing severe pneumonia with a high infection rate globally. To better understand the pathogenesis caused by SARS-CoV-2, we developed rhesus macaque model to mimic natural via nasal route, resulting in SARS-CoV-2 virus shedding nose and stool up 27 days. Importantly, observed pathological progression of marked interstitial infected animals on 5–7 dpi, dissemination widely occurring lower respiratory tract lymph nodes, viral RNA was consistently...
Gut microbiota dysbiosis plays an important role in the progression of non-alcoholic fatty liver disease (NAFLD), and no approved drugs are available for NAFLD treatment. In this study, we aimed to explore dynamic changes gut at different stages determine whether ursodeoxycholic acid (UDCA) could improve histopathological features steatohepatitis (NASH) mice induced by a high-fat high-cholesterol (HFHC) diet its impact on microbiota. 6-week-old male C57BL/6 were fed with HFHC or normal 12,...
Abstract SARS-CoV-2 can infect many domestic animals, including dogs. Herein, we show that dog angiotensin-converting enzyme 2 (dACE2) bind to the spike (S) protein receptor binding domain (RBD), and both pseudotyped authentic dACE2-expressing cells. We solved crystal structure of RBD in complex with dACE2 found total number contact residues, atoms, hydrogen bonds salt bridges at interface this are slightly fewer than those human ACE2 (hACE2). This result is consistent fact affinity lower...
An unacceptable bitter taste limits the application of luteolin in healthier food systems. In this study, a bitterness-masking assessment was performed on whey protein isolate-coated liposomes loaded with (WPI-coated liposomes) using an electronic tongue and human sensory test. The physical properties WPI-coated colloidal nanocarrier were characterized by zeta potential, average diameter, distribution, morphology analyses. results indicated that systems exhibited uniformly dispersed...
Total hip arthroplasty and total knee are widely performed worldwide. Patients undergoing or often discharged after a short hospital stay. Using information communication technologies, such as mobile applications, to provide rehabilitation services remotely may be strategy support patients' postoperative recovery.This study aimed evaluate the effectiveness of programme delivered via application among Chinese patients arthroplasty.Randomised controlled trial.A teaching in Shanghai,...
A TCM formula has played an important role in the treatment of COVID-19 China. However, mechanism action is still unclear.
Background/Objectives: Coping strategies are influenced by sociocultural factors, and an understanding of how the Brief-COPE functions within Chinese student population is important for its validity reliability. This study aimed to explore factor structure Brief Orientation Problems Experienced Inventory (Brief-COPE) in nursing students. Methods: A cross-sectional design was adopted. total 284 college students, aged 18 years or older, were recruited from a medical university China using...
Abstract Background An increasing number of patients are discharged from a total hip or knee arthroplasty with short length hospital stay. Technologies, such as mobile applications, used to provide remote support patients’ postoperative rehabilitation. Patients’ experiences receiving application-based rehabilitation after have not been investigated extensively. Methods This was qualitative descriptive study. Twenty-five participants who had completed programme for were recruited....
The global increase in total hip or knee arthroplasty has led to concern about the provision of postoperative rehabilitation. Telerehabilitation may be a strategy meet patients' requirements for rehabilitation after arthroplasty. This study aims investigate effectiveness telerehabilitation programme delivered via mobile application WeChat patients on following outcomes: self-efficacy, physical function, pain, depression, anxiety and health-related quality life.This is single-centre,...
Elevated serum ferritin (SF), also defined as hyperferritinemia, is commonly seen in patients with nonalcoholic fatty liver disease (NAFLD). However, the clinical significance of SF NAFLD remains controversial. The aim this study was to characterize elevated and explore association hyperferritinemia severity proved by biopsy Chinese population.A total 136 were enrolled. demographic, anthropometric, historic, laboratory, histological characteristics compared between normal groups. independent...
Abstract The great shortage of human hepatic cells makes it desirable to generate extrahepatic stem or precursor cells. In recent years, has been reported that multipotential mesenchymal (hMSCs) differentiate into hepatocyte‐like fetal lung is one the largest organs containing many MSCs can be easily obtained. Whether from hepatocytes bile duct an important issue in basic medicine and clinical application. We isolated cells, expanded analyzed them. At passage 4, their morphologic,...
Abstract Objectives To evaluate the diagnostic value of luteinizing hormone (LH) and LH/follicle stimulating (FSH) ratio at 60 min after gonadotropin-releasing analogs (GnRHa) stimulation test for central precocious puberty (CPP) in girls. Methods Two hundred fifty-seven girls, aged 3 to 7.5 y, suspected authors’ hospital from April 2020 through November 2023 were enrolled study. The blood was taken 0, 30, GnRHa test, LH LH/FSH detected by chemiluminescence assay. efficacy analysed...