A5004358589- Sports injuries and prevention
- Cardiovascular Effects of Exercise
- Cardiovascular and exercise physiology
- Muscle metabolism and nutrition
- Exercise and Physiological Responses
- Muscle Physiology and Disorders
- Knee injuries and reconstruction techniques
- High Altitude and Hypoxia
- Long-Term Effects of COVID-19
- Body Composition Measurement Techniques
- Childhood Cancer Survivors' Quality of Life
- Sports Performance and Training
- Heart Rate Variability and Autonomic Control
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Advanced Neuroimaging Techniques and Applications
- Hormonal and reproductive studies
- Metabolomics and Mass Spectrometry Studies
- Neuroscience of respiration and sleep
- Cardiovascular Function and Risk Factors
- COVID-19 and Mental Health
- Peripheral Nerve Disorders
- Cardiac Health and Mental Health
- Adipose Tissue and Metabolism
- Adolescent and Pediatric Healthcare
- Tendon Structure and Treatment
Heidelberg University
2016-2025
University Hospital Heidelberg
2016-2025
Universitätsklinikum Tübingen
2020
University of Applied Sciences for Public Administration and Management
2019
National Center for Tumor Diseases
2015
Heidelberg University
2013
Chirurgische Universitätsklinik Heidelberg
2010-2011
Martin Luther University Halle-Wittenberg
2010
Background Self-reported health problems following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are common and often include relatively non-specific complaints such as fatigue, exertional dyspnoea, concentration or memory disturbance sleep problems. The long-term prognosis of post-acute sequelae COVID-19/post-COVID-19 (PCS) is unknown, data finding correlating organ dysfunction pathology with self-reported symptoms in patients non-recovery from PCS scarce. We wanted...
Context Dehydration is assumed to be a major adverse effect associated with rapid loss of body mass for competing in lower weight class combat sports. However, the effects such cutting on fluid balance real-life setting are unknown. Objective To examine 5% or greater within few days before competition water, blood volume, and plasma volume elite amateur boxers. Design Case-control study. Setting Sports medicine laboratory. Patients Other Participants Seventeen male boxers (age = 19.2 ± 2.9...
Rapid body mass loss (RBML) before competition was found to decrease hemoglobin (Hbmass ) in elite boxers. This study aimed investigate the underlying mechanisms of this observation. Fourteen well-trained combat athletes who reduced competitions (weight group, WLG) and 14 did not practice RBML (control CON) were tested during an ordinary training period (t-1), 1-2 days official (after 5-7 WLG, t-2), after a post-competition (t-3). In (-5.5%, range: 2.9-6.8 kg) Hbmass (-4.1%) significantly (P...
An infection with SARS-CoV-2 can lead to a variety of symptoms and complications, which impair athletic activity.
Abstract Background Impaired left and right ventricular function have been observed mainly in hospitalized patients with acute SARS-CoV-2 infection. The long-term cardiac sequelae not yet conclusively clarified large, well-defined cohorts. In addition, it is certain whether related to persistent cardiopulmonary symptoms or reduced exercise capacity after COVID-19. Purpose Differences structure suspected post-COVID syndrome (PCS) recovered control (CON) were analysed regard the association...
Abstract Little is known about the exercise‐induced adaptations of metabolome in endurance and strength athletes comparison with sedentary subjects. In order to analyze effects, quantitative, targeted metabolomics (Biocrates MxP® Quant 500) were performed plasma samples before after one bout or resistance exercise (RE) 12 strength‐trained weightlifters (ST), 10 endurance‐trained runners (ET) controls (CG) at end each three characteristic training phases. Performance anthropometric data...
Impaired left and right ventricular (LV/RV) function during acute SARS-CoV-2 infection has been predominantly reported in hospitalized patients, but long-term cardiac sequelae large, well-characterized cohorts remain inconclusive. This study evaluated structure individuals with post-Coronavirus disease (COVID) syndrome (PCS) compared to recovered controls (CON), focusing on associations cardiopulmonary symptoms rapid physical exhaustion (RPE). multicenter, population-based included 1154...
Long- and post-COVID syndrome (PCS) affect at least 65 million individuals globally, with an estimated incidence of 10% among over 651 documented cases SARS-CoV-2 infection. PCS impacts nearly every organ system, posing significant challenges for healthcare systems patients. Despite this, effective guidelines multimodal training or rehabilitation remain absent. The app-based physical intervention long- treatment (A PILOT) study is a prospective, multicentre, two-armed, randomised controlled...
Dietary intake, vitamin status and oxidative stress were evaluated in 17 elite male boxers. Ten of them frequently reduced body weight rapidly before competitions (Weight Loss Group) 7 did not practice rapid loss (Control Group). Food record checklists, blood samples for determination plasma glutathione levels obtained during a week maintenance, pre-competition post-competition week. The average dietary intakes both groups 33 ± 8 kcal·kg−1, 3.7 1.1 g·kg−1 carbohydrates, 1.5 0.4 protein, 1.2...
ABSTRACT Purpose Protracted quadriceps muscle atrophy is observed after anterior cruciate ligament reconstruction (ACL-R). The aim of this study was to assess if strength training with eccentric overload (CON/ECC + ) more efficient induce regeneration ACL-R than conventional concentric/eccentric (CON/ECC) training. Methods Biopsies from the vastus lateralis were obtained 37 recreational athletes 12 wk regular rehabilitation and again twice a week either CON/ECC ( n = 16) or 21) one-legged...
Objective: It is unclear whether and to what extent COVID-19 infection poses health risks a chronic impairment of performance in athletes. Identification individual risk an important decision-making basis for managing the pandemic with SARS-CoV-2 sports return play (RTP). Methods: This study aims 1) analyze longitudinal rate seroprevalence German athletes, 2) assess health-related consequences athletes infected SARS-CoV-2, 3) reveal effects general cleared on exercise performance. CoSmo-S...
Abstract Objective To assess risk factors for persistence vs improvement and to describe clinical characteristics diagnostic evaluation of subjects with post-acute sequelae COVID-19/post-COVID-19 syndrome (PCS) persisting more than one year. Design Nested population-based case-control study. Setting Comprehensive outpatient assessment, including neurocognitive, cardiopulmonary exercise, laboratory testing in four university health centres southwestern Germany (2022). Participants PCS cases...
Dilated cardiomyopathy (DCM) is a leading cause of heart failure, particularly in younger individuals. Low physical strength global risk factor for cardiovascular mortality, and activity healthy lifestyle have been shown to improve outcomes patients with failure. However, inappropriate exercise may increase the arrhythmias certain individuals DCM. The determinants predicting individual risks this setting are poorly understood, clinicians hesitant recommend sports patients. activeDCM trial...
To evaluate the reliability and validity of a standardized ultrasound examination protocol for measuring vastus lateralis muscle size.Prospective cohort study.Sixteen staff members university hospital Heidelberg.Muscle thickness, cross-sectional area subcutaneous adipose tissue thickness were measured at 3 sites on right left muscle. Ultrasound measurements collected by 2 independent investigators different days compared with magnetic resonance imaging measurements.Intraclass correlation...
Repeated biopsy sampling from one muscle is necessary to investigate muscular adaptation different forms of exercise as thought be the result cumulative effects transient changes in gene expression response single bouts. In a crossover study, we obtained four fine needle biopsies vastus lateralis 11 male subjects (25.9 ± 3.8 yr, 179.2 4.8 cm, 76.5 7.0 kg), taken before (baseline), 1, 4, and 24 h after bout squatting performed conventional or whole body vibration exercise. To if repeated has...
This document replaces the DGP recommendations published in 1998. Based on recent studies and a consensus conference, indications, choice performance of adequate exercise testing method its necessary technical staffing setting are discussed. Detailed provided: for arterial blood gas analysis right heart catherterization during exercise, 6-minute walk test, spiroergometry, stress echocardiography. The correct use different tests is discussed specific situations respiratory medicine: induced...
Background: An exaggerated blood pressure response (EBPR) during exercise testing is not well defined, and several thresholds are used in different studies recommended guidelines. Methods: Competitive athletes of any age without known arterial hypertension who presented for preparticipation screening were included the present study categorized EBPR according to American Heart Association (AHA), European Society Cardiology (ESC), College Sports Medicine (ACSM) guidelines as systolic...
Iron is an important micronutrient in pathways of energy production, adequate nutrient intake and its balance essential for optimal athletic performance. However, large studies elucidating the impact iron deficiency on athletes' performance are sparse.
Technological advances allow for recording and sharing health-related data in a patient-centric way using smartphones wearables. Secure of such patient-generated with physicians would enable close management individual health trajectories, monitoring risk factors, asynchronous feedback. However, most remote patient (RPM) systems currently available are not fully integrated into hospital IT or lack design.
This document replaces the DGP recommendations published in 1998 and 2013. Based on recent studies a consensus conference, indications, choice performance of adequate exercise testing method its necessary technical staffing setting are discussed. Detailed provided: for blood gas analysis right heart catheterization during exercise, walk tests, spiroergometry, stress echocardiography. The correct use different tests is discussed specific situations respiratory medicine: induced asthma,...