A5022512429- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- COVID-19 and Mental Health
- SARS-CoV-2 and COVID-19 Research
- Respiratory Support and Mechanisms
- COVID-19 and healthcare impacts
- Sepsis Diagnosis and Treatment
- Fibromyalgia and Chronic Fatigue Syndrome Research
- COVID-19 diagnosis using AI
- Intensive Care Unit Cognitive Disorders
- Antibiotic Resistance in Bacteria
- Antibiotic Use and Resistance
- Cardiovascular Function and Risk Factors
- HIV Research and Treatment
- Viral Infections and Outbreaks Research
- Vibrio bacteria research studies
- HIV/AIDS drug development and treatment
- Bacterial Identification and Susceptibility Testing
- HIV/AIDS Research and Interventions
- Viral-associated cancers and disorders
- Pneumonia and Respiratory Infections
- Cardiovascular Effects of Exercise
- Streptococcal Infections and Treatments
- Anesthesia and Sedative Agents
- Cytomegalovirus and herpesvirus research
University of Tübingen
2021-2025
University Children's Hospital Tübingen
2021-2025
German Center for Infection Research
2021-2024
University of Oxford
2021
Goethe University Frankfurt
2014
University Hospital Frankfurt
2014
Background Self-reported health problems following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are common and often include relatively non-specific complaints such as fatigue, exertional dyspnoea, concentration or memory disturbance sleep problems. The long-term prognosis of post-acute sequelae COVID-19/post-COVID-19 (PCS) is unknown, data finding correlating organ dysfunction pathology with self-reported symptoms in patients non-recovery from PCS scarce. We wanted...
Abstract Background Impaired left and right ventricular function have been observed mainly in hospitalized patients with acute SARS-CoV-2 infection. The long-term cardiac sequelae not yet conclusively clarified large, well-defined cohorts. In addition, it is certain whether related to persistent cardiopulmonary symptoms or reduced exercise capacity after COVID-19. Purpose Differences structure suspected post-COVID syndrome (PCS) recovered control (CON) were analysed regard the association...
Impaired left and right ventricular (LV/RV) function during acute SARS-CoV-2 infection has been predominantly reported in hospitalized patients, but long-term cardiac sequelae large, well-characterized cohorts remain inconclusive. This study evaluated structure individuals with post-Coronavirus disease (COVID) syndrome (PCS) compared to recovered controls (CON), focusing on associations cardiopulmonary symptoms rapid physical exhaustion (RPE). multicenter, population-based included 1154...
Introduction Delirium is recognized as a severe complication of coronavirus-disease-2019 (COVID-19). COVID-19-associated delirium has been linked to worse patient outcomes and considered be multifactorial origin. Here we sought evaluate the incidence risk factors in hospitalized COVID-19 patients, along with its impact on clinical outcome. Methods Consecutive adult patients admitted tertiary academic referral hospital between March 1 st December 31 , 2020 were included. Potential for...
OPINION article Front. Psychiatry, 21 May 2021 | https://doi.org/10.3389/fpsyt.2021.677934
Abstract Purpose While more advanced COVID-19 necessitates medical interventions and hospitalization, patients with mild do not require this. Identifying at risk of progressing to might guide treatment decisions, particularly for better prioritizing in need hospitalization. Methods We developed a machine learning-based predictor deriving clinical score identifying asymptomatic/mild COVID-19. Clinical data from SARS-CoV-2 positive the multicenter Lean European Open Survey on Infected Patients...
This study aimed to determine rates and risk factors of extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-PE) acquisition transmission within households after hospital discharge an ESBL-PE-positive index patient.Two-year prospective cohort in five European cities. Patients colonized with ESBL-producing Escherichia coli (ESBL-Ec) or Klebsiella pneumoniae (ESBL-Kp), their household contacts were followed up for 4 months the case. At each follow up, participants provided a faecal...
Since the introduction of highly active antiretroviral therapy (HAART) (1) and later on availability anti-CD20 monoclonal antibody treatment (2), therapeutic options as well prognosis AIDS related lymphoma (ARL) have been improved. There is however no uniform agreement how to treat patients who do not achieve a partial remission, experience relapse or very aggressive subtypes. Autologous hematopoietic stem cell transplantation (ASCT) has become an option for those patients. We...
Introduction HIV infection is accompanied by a variety of neurological disorders. Depression cell‐mediated immunity followed the development central nervous system opportunistic infections/tumours, and frequently occurrence AIDS dementia complex (ADC). However, pathophysiology emergence neuro‐AIDS still unknown. Despite cognitive impairments, early diagnosis, objectification quantification existence extent this impairment during are difficult to recognize in each individual case. To support...
Objectives: For 475 ESBL-producing Escherichia coli (ESBL-Ec), and 171 Klebsiella pneumoniae (ESBL-Kp) collected from human carriers, the human-polluted (hp)-environment, food: (i) to compare antimicrobial resistance gene (ARG) content, (ii) assess clonal relationships between non-human isolates. Methods: Two prospective multicentre cohorts were assessed: colonised hospitalised index-subjects household contacts, long-term care facility (LTCF) residents. Additionally, linked hp-environment...
To analyze the longitudinal epidemiology and antimicrobial resistance (AMR) patterns of Gram-negative bloodstream infections (BSI) in Germany.
Courses of SARS-CoV-2 infections are highly variable, ranging from asymptomatic to lethal COVID-19. Though research has shown that host genetic factors contribute this variability, cohort-based joint analyses variants the entire allelic spectrum in individuals with confirmed still lacking. Here, we present results whole genome sequencing 1,220 mainly vaccine-naïve infection, including 827 hospitalized COVID-19 cases. We observed presence autosomal-recessive or likely compound heterozygous...