Background/Objectives: Adults with hearing loss demonstrate poorer overall health outcomes (e.g., physical health, cognitive functioning and wellbeing) lower levels of activity/function compared to those without loss. Hearing aids have the potential improve wellbeing factors, but there is a dearth evidence on their impact outcomes. Evidence association between aid provision activity mostly limited cross-sectional studies. This research aimed assess whether study can be performed identify...

Purpose: Higher accelerometer-assessed volume and intensity of physical activity (PA) have been associated with a longer life expectancy but can be difficult to translate into recommended doses PA.We aimed to: (a) improve interpretability by producing UK Biobank age-referenced centiles for PA intensity; (b) inform public-health messaging examining how adding quantities moderate vigorous affect intensity.Methods: 92,480 UK-Biobank participants aged 43-80 wrist-worn accelerometer data were...

To describe age-related differences in the absolute and relative intensity of physical activity (PA) associations with mortality. UK Biobank participants accelerometer-assessed PA (mg) fitness data (N=11 463; age: 43-76 years) were included. The distribution was expressed terms. outcome volume (average acceleration) lower increasing age (~-0.03 to -0.04 SD mean value across all ages per year; p<0.001) but by markedly smaller women (-0.003 SD; p<0.184) men (-0.012 p<0.001). Absolute higher...

Allelic variation in the size of insulin (INS) variable number tandem repeat (VNTR) correlates with expression both INS pancreas and thymus IGF2 (the gene downstream INS) placenta. In addition, shorter, class I alleles are associated type 1 diabetes, whereas longer, III 2 polycystic ovary syndrome (PCOS), at birth. Parent-of-origin effects have been reported for diabetes PCOS, thus implicating a role genomic imprinting these phenotypes. mice, Ins2 is imprinted paternally expressed yolk sac....

Abstract Background Mobile health technologies have advanced to now allow monitoring of the acute physiological responses lifestyle behaviours. Our aim was explore how people engaged with real-time feedback on their physical activity and glucose levels over several weeks. Methods Semi-structured interviews 26 participants (61.5% female, 56.6 years) at moderate-to-high risk developing type 2 diabetes were conducted. Interviews completed after took part in an intervention comprising a flash...

Background Self-monitoring of behavior (namely, diet and physical activity) physiology glucose) has been shown to be effective in type 2 diabetes (T2D) prediabetes prevention. By combining self-monitoring technologies, the acute physiological consequences behaviors could shown, prompting greater consideration activity levels today, which impact risk developing years or decades later. However, until recently, commercially available technologies have not able show individuals health benefits...

Objectives To determine whether quantifying both the absolute and relative intensity of accelerometer-assessed physical activity (PA) can inform PA interventions. We hypothesised that individuals whose free-living is at a low are more likely to increase in response an intervention, as they have spare capacity. Method conducted secondary data analysis 12-month randomised controlled trial, Physical Activity after Cardiac EventS, which was designed but showed no improvement. Participants...

Background: The constructs and interdependency of physical behaviors are not well described the complexity activity (PA) data analysis remains unexplored in COPD. This study examined interrelationships 24-hour investigated their associations with participant characteristics for individuals mild–moderate airflow obstruction healthy control subjects. Patients methods: Vigorous PA (VPA), moderate-to-vigorous (MVPA), light (LPA), stationary time (ST), average movement intensity (vector magnitude...

Albert Einstein taught us that “everything is relative.” People’s experience of physical activity (PA) no different, with “relativism” particularly pertinent to the perception intensity. Markers absolute and relative intensities PA have different but complimentary utilities, intensity considered best for guideline adherence personalized exercise prescription. Under paradigm as medicine, our Technical Note proposes a method synchronizing accelerometry incremental shuttle walking test...

Background: Unfortunately, global efforts to promote “how much” physical activity people should be undertaking have been largely unsuccessful. Given the difficulty of achieving a sustained lifestyle behavior change, many scientists are reexamining their approaches. One such approach is focus on understanding context (ie, where, when, and with whom) view identifying promising intervention targets.

Physical activity (PA) intensity of people living with chronic obstructive pulmonary disease (COPD) is typically evaluated using thresholds developed in younger, healthier populations greater exercise capacity and free from respiratory symptoms. This study therefore compared (i) PA differences between COPD non-COPD controls both traditional threshold-free metrics that represent the volume whole profile, (ii) explored influence on observed differences. Moderate-to-vigorous physical (MVPA),...

When launched, FreeStyle Libre (FSL; a flash glucose monitor) onboarding was mainly conducted face-to-face. The COVID-19 pandemic accelerated change to online starts with patients directed videos such as Diabetes Technology Network UK for education. We an audit evaluate glycemic outcomes in people who were onboarded face-to-face versus those remotely and determine the impact of ethnicity deprivation on outcomes.People living diabetes started using FSL between January 2019 April 2022, had...

Acute reductions in postprandial glucose excursions because of movement behaviors have been demonstrated experimental studies but less so free-living settings.The objective this study was to explore the nature acute stimulus-response model between accelerometer-assessed physical activity, sedentary time, and variability over 13 days nondiabetic adults.This measured interstitial continuously 29 participants (mean age years: 44.9 [SD 9.1]; female: 59%, 17/29; white: 90%, 26/29; mean body mass...

Background: The recent surge in commercially available wearable technology has allowed real-time self-monitoring of behavior (eg, physical activity) and physiology glucose levels). However, there is limited neuroimaging work (ie, functional magnetic resonance imaging [fMRI]) to identify how people's brains respond receiving this personalized health feedback impacts subsequent behavior. Objective: Identify regions the brain activated examine associations between activation Methods: This was a...

Introduction Increasing physical activity (PA) reduces the risk of developing diabetes, highlighting role preventive medicine approaches. Changing lifestyle behaviours is difficult and often predicated on assumption that individuals are willing to change their lifestyles today reduce disease years or even decades later. The self-monitoring technologies tested in this study will present PA feedback real time, parallel with acute physiological data. Presenting immediate health benefits being...

Like many wearables, flash glucose monitoring relies on user compliance and is subject to missing data. As recent research beginning utilise technologies as behaviour change tools, it important understand whether data are tolerable. Complete Freestyle Libre files were amputed remove 1-6 h of both at random over mealtimes (breakfast, lunch, dinner). Absolute percent errors (MAPE) intraclass correlation coefficients (ICC) calculated evaluate agreement reliability. Thirty-two (91%) participants...

The dataset consists of a densely phenotyped sample adults collected from March to August 2014. captures behavioural, physical, physiological and psychosocial characteristics individuals with without General Practitioner diagnosis chronic obstructive pulmonary disease (COPD). Data were at Glenfield Hospital on 436 (139 COPD patients 297 apparently healthy adults) aged 40–75 years, residing in Leicestershire Rutland, United Kingdom. includes seven days raw wrist-worn accelerometry, venous...

The response to COVID-19 resulted in behavioral restrictions tackle the spread of infection. Initial data indicates that step counts were impacted by lockdown restrictions; however, there is little evidence regarding changes light and moderate vigorous physical activity (MVPA) intensities. In this study, participants asked provide longitudinal wearable from Fitbit devices over a period 30 weeks, December 2019 June 2020. Self-assessed key worker status was captured, along with estimates...

Abstract Aim To assess the differential association of risk factors with severe and non‐severe hypoglycaemia. Materials Methods The Hypoglycaemia Assessment Tool study evaluated hypoglycaemia over a 4‐week period in patients type 1 diabetes (T1D) 2 (T2D) on insulin 24 countries. Negative binomial regressions were applied to examine associations several Results median age was 41 years 5949 T1D 62 12 914 T2D. rates hypoglycaemic 5.57 1.40 episodes per person T2D, respectively; corresponding...