- Ruminant Nutrition and Digestive Physiology
- Reproductive Physiology in Livestock
- Genetic and phenotypic traits in livestock
- Agronomic Practices and Intercropping Systems
- Agriculture Sustainability and Environmental Impact
- Effects of Environmental Stressors on Livestock
- Animal Genetics and Reproduction
- Animal Nutrition and Physiology
- CRISPR and Genetic Engineering
- Phytase and its Applications
- Bioenergy crop production and management
- Moringa oleifera research and applications
- Isotope Analysis in Ecology
- Agroforestry and silvopastoral systems
- Animal Behavior and Welfare Studies
- Milk Quality and Mastitis in Dairy Cows
- Virus-based gene therapy research
- Crop Yield and Soil Fertility
- RNA Research and Splicing
- RNA regulation and disease
- Soil Carbon and Nitrogen Dynamics
- Botany and Plant Ecology Studies
- Agricultural pest management studies
- Prion Diseases and Protein Misfolding
- Forest ecology and management
Aarhus University
2012-2025
Cambridge University Press
2015
New York University Press
2015
Aarhus University Hospital
2002
The objective of the present study was to investigate effect individual and combined use dietary fat, nitrate 3-nitrooxypropanol (3-NOP) on dairy cows' enteric methane (CH4) emission production performance. Twenty-four primiparous 24 multiparous Danish Holstein cows (111 ± 44.6 d in milk; mean SD) were included an incomplete 8 × Latin square design with 6 21 periods. Dietary treatments organized a 2 factorial arrangement aiming for levels FAT (30 or 63 g crude fat/kg DM; LF HF,...
We describe a new human isoform, GFAPε, of the intermediary filament protein GFAP (glial fibrillary acidic protein). GFAPε mRNA is result alternative splicing and polyadenylation signal, thus has C-terminal sequence. This provides with capacity for specific binding presenilin proteins in yeast <i>in vitro</i>. Our observations suggest direct link between presenilins cytoskeleton where incorporated. Mutations are associated Alexander disease Alzheimer's disease, respectively. Accordingly,...
This experiment examined how supplementation of Bovaer in dietary rations with high proportion grass-clover silage affected DMI, milk production, and gas emissions lactating dairy cows, whether the effect was uniform across parity stage lactation. Forty-eight Holstein cows (equally balanced between primiparous multiparous early mid-late lactation) were included a 4 × Latin square design, 2 factorial arrangement treatments. The first factor different sources silage, spring growth or regrowth,...
Mutations in the amyloid-β protein precursor gene (AβPP), presenilin 1 (PSEN1) or 2 (PSEN2) that increase production of AβPP-derived peptide Aβ42 cause early-onset Alzheimer's disease. Rodent models disease show further and ea rlier brain pathology can be obtained by coexpressing AβPP PSEN1 mutations. To generate such elevated level a large animal model, we produced Göttingen minipigs carrying their genome one copy human cDNA with Met146Ile (PSEN1M146I) mutation three copies AβPP695...
This experiment investigated the variation in enteric methane production and associated gas exchange parameters, nutrient digestibility, rumen fermentation, microbiome when a range of silages based on different forage types (grass or clover), species within 2 types, were fed as sole feed to heifers. Three grass (perennial ryegrass, festulolium, tall fescue) clover (red white clover) included. Perennial ryegrass was harvested at maturity stages primary growth, once 4 cuts festulolium fescue 3...
Targeted transgenesis using site-specific recombinases is an attractive method to create genetically modified animals as it allows for integration of the transgene in a pre-selected transcriptionally active genomic site. Here we describe application recombinase-mediated cassette exchange (RMCE) cells from Göttingen minipig with four RMCE acceptor loci, each containing green fluorescence protein (GFP) marker gene driven by human UbiC promoter. The loci segregated independent other, and...
The objective of the current study was to examine effect fibrous pulp and partial substitution soybean meal with green protein concentrate from biorefining grass-clover on dry matter intake, milk production, digestibility, eating behavior in dairy cows compared untreated silage meal. Biorefining occurred right after harvest a production-scale twin-screw press. pressing separated into juice. juice fermented using lactic acid bacteria for precipitation then decanted, precipitate heat dried...
Reelin is an extracellular glycoprotein of crucial importance in the developmental organisation neurons mammalian cerebral cortex and other laminated brain regions. The pig possesses a gyrencephalic that bears resemblance to human brain. In order establish animal model for neuronal migration disorders pig, we have studied expression pattern structure during development. We determined sequence mRNA protein identified high degree homology Reelin. A peak present period major neurogenesis...
Methane constitutes a significant loss of feed gross energy in ruminants, and there is an ongoing struggle for identifying animal characteristics feasible documentation National Greenhouse Gas Inventories. The aim the current study was to develop model that predicts methane conversion factor (Ym, % energy) dairy cows on basis data obtained from range our respiration studies, and, subsequently, use this predict Ym Holstein Jersey compiled average national farm dry matter intake, yield...
The objective of this study was to investigate the effects heat treatment (toasting) and particle size alterations (grinding; rolling) on nutrient utilization, ruminal fermentation, supply metabolizable protein (MP), interaction between processing conditions fava beans forage type. Six Danish Holstein dairy cows fitted with ruminal, duodenal, ileal cannulas were used in a 6 × 4 incomplete Latin square design periods 21-d duration. Cows fed ad libitum experimental diets: diets high either...
Enteric CH4 produced from dairy cows contributes to the greenhouse gas emission anthropogenic sources. Recent studies have shown that selection of lower emitting is possible, but this would be simpler if performance measures already recorded on farm could used, instead measuring individual cows. These used for low The aim analysis was quantify how much between-cow variation in production can explained by measures. A data set with 3 experiments, a total 149 lactating repeated measures,...
The aim of the study was to examine ability Göttingen minipigs acquire an olfaction-based operant conditioning task and determine detection threshold for ethyl acetate ethanol. We used automated olfactometer developed rodents train test 14 pigs. Odor sampling reliable responding were obtained after three fifteen 160-trial sessions. Successful transfer from ethanol achieved in 1–4 Detection varied between 10−2% 10−6% v/v 0.1% 5 × v/v. results provide evidence that can successfully 2-odorant...
Measuring feed intake accurately is crucial to determine efficiency and for genetic selection. A system using three-dimensional (3D) cameras deep learning algorithms can measure the volume of in dairy cows, but now, has not been validated expressed as weight feed. The aim this study was validate predicted from 3D with actual measured weight. It hypothesised that diet-specific coefficients are necessary predicting changes weight, relationship between curvilinear throughout day, manually...
Automated measurements of the ratio concentrations methane and carbon dioxide, [CH
Dietary carbohydrate manipulation can be used to reduce enteric CH4 emission, but there is a lack of studies on the interaction different types carbohydrates that affect feed intake and ruminal fermentation. Understanding this necessary make most out mitigation feeding strategies using dietary carbohydrates. The aim study was test effect milk production response when cows were fed either grass-clover (GCS) or corn silage (CS) as sole forage source (55% dry matter, DM), in combination with...