A5073004079- Child Nutrition and Water Access
- Gestational Diabetes Research and Management
- Pregnancy and preeclampsia studies
- Birth, Development, and Health
- Iron Metabolism and Disorders
- Food Security and Health in Diverse Populations
- Obesity, Physical Activity, Diet
- Global Maternal and Child Health
- Folate and B Vitamins Research
- Pregnancy and Medication Impact
- Adolescent Sexual and Reproductive Health
- Trace Elements in Health
- Infant Nutrition and Health
- Hemoglobinopathies and Related Disorders
- School Health and Nursing Education
- Poverty, Education, and Child Welfare
- Breastfeeding Practices and Influences
- Pregnancy-related medical research
- COVID-19 Impact on Reproduction
- HIV-related health complications and treatments
- Vitamin D Research Studies
- HIV/AIDS Research and Interventions
- Infant Development and Preterm Care
- Preterm Birth and Chorioamnionitis
- Maternal and fetal healthcare
Harvard Global Health Institute
2015-2024
Harvard University
2013-2024
Massachusetts Department of Public Health
2022-2023
Harvard University Press
2020
Boston University
2016-2019
Purpose Diet is a potentially modifiable risk factor for endometriosis. It has been hypothesized that vitamins C, E, and the B may influence factors involved in pathogenesis of endometriosis, such as oxidative stress steroid hormone metabolism. In this large, prospective cohort study, we examined relation between intake vitamins, use multivitamin supplements diagnosis Methods Data were collected from women Nurses' Health Study II 1991 2005. was assessed via food frequency questionnaire....
The objective of this study was to evaluate gender differences in nutritional status, dietary intake, physical activity and hand hygiene among adolescents from diverse geographical settings sub-Saharan Africa.This utilised cross-sectional data six countries (Burkina Faso, Ethiopia, Ghana, Nigeria, Tanzania Uganda) within the ARISE Adolescent Health Survey (n = 7625). Body mass index (BMI) calculated using measured heights weights, z-scores were based on 2007 WHO growth standards for age sex....
To measure health-related behaviours and risk factors among sub-Saharan African adolescents.Cross-sectional study in nine communities Burkina Faso, Ethiopia, Eswatini, Ghana, Nigeria, Tanzania Uganda between 2015 2017. Community-representative samples of males females 10-19 years age were selected. All used a uniform questionnaire that was adapted from the WHO Global School-based Student Health Survey. Weighted prevalence estimates 95% confidence intervals calculated for each indicator...
Introduction Gestational weight gain (GWG) has important implications for maternal and child health is an ideal modifiable factor preconceptional antenatal care. However, the average levels of GWG across all low-income middle-income countries world have not been characterised using nationally representative data. Methods estimates time were computed data from Demographic Health Surveys Program. A hierarchical model was developed to estimate mean total in year 2015 facilitate cross-country...
Introduction As many as 250 million children under the age of 5 may not be reaching their full developmental potential partly due to poor nutrition during pregnancy and first 2 years life. Micronutrients, including vitamin B 12 , are important for development brain structure function; however, timing, duration severity deficiencies alter impact on functional outcomes. Consequently, fully explore effect cognitive function, it is crucial measure neurodevelopment at different ages, in...
The ARISE Network Adolescent Health Study is an exploratory, community-based survey of 8075 adolescents aged 10-19 in 9 communities 7 countries: Burkina Faso, Eswatini, Ethiopia, Ghana, Nigeria, Tanzania and Uganda. Communities were selected opportunistically existing population cohorts maintained by health demographic surveillance systems (HDSSs). study intended to serve as a first round data collection for African adolescent cohorts, with the overarching goal generating on health-related...
National estimates suggest that COVID-19 vaccination coverage among pregnant persons is lower those identifying as Hispanic or Latino (Hispanic) and non-Hispanic Black African American. When examining during pregnancy by race ethnicity, however, data are typically limited to large, aggregate categories might obscure within-group inequities. To address this, Massachusetts examined combinations of 12 racial 34 ethnic groupings. Among 102,275 with a live birth in May 1, 2021-October 31, 2022,...
Background and Methods: This cross-sectional study aimed at determining the prevalence risk factors for severe anemia, microcytic normocytic anemia among HIV-infected individuals aged >15 years. Univariate multivariate analyses were performed to identify anemia. Results: Data from 40 408 patients analyzed, showing an overall of 22% The developing increased by 49% with a body mass index <18.5 kg/m 2 , approximately 2-fold World Health Organization (WHO) stage III, 3-fold WHO IV illness....
Vitamin A and zinc are important for immune function may improve host defense against malaria reduce the risk of adverse pregnancy outcomes. Our objective was to determine whether daily oral supplementation with either or both nutrients starting in first trimester reduces placental We undertook a randomized, double-blind placebo-controlled trial factorial design among 2,500 human immunodeficiency virus–negative primigravid secundigravid pregnant women their Dar es Salaam, Tanzania. randomly...
Our objective was to assess the impact of preconceptional heme and non-heme iron on gestational diabetes mellitius (GDM) in Boston University Slone Epidemiology Birth Defects Study (BDS). This retrospective cohort analysis included 7229 participants enrolled BDS between 1998 2008 who gave birth non-malformed infants were free pre-existing diabetes. All data collected through structured interviews conducted within 6 months delivery. Calorie-adjusted multivariable odds ratios (ORs) 95%...
Abstract Some evidence suggests that aflatoxin may contribute to the high prevalence of stunting observed in low‐income countries. Whereas several studies have been conducted West Africa, fewer exist East Africa and even nonagricultural contexts. We analyzed serum samples from 400 iron‐replete, nonanemic pregnant women a cohort Dar es Salaam, Tanzania determine extent magnitude exposure study relationship between levels utero infant birth growth outcomes. Ninety‐nine percent had detectable...
Abstract Objectives We analysed mutually comparable surveys on adolescent attitudes and behaviours from nine sites in seven sub‐Saharan African countries, to determine the relationship between school enrolment health outcomes. Methods Data Africa Research, Implementation Science, Education Network cross‐sectional were used examine associations of current enrolment, self‐reported general four major domains: (i) sexual reproductive health; (ii) nutrition non‐communicable diseases; (iii) mental...
Gestational weight gain (GWG) is associated with fetal and newborn health; however, data from sub-Saharan Africa are limited.We used a prenatal micronutrient supplementation trial among cohort of human immunodeficiency virus-negative pregnant women in Dar es Salaam, Tanzania to estimate the relationships between GWG neonatal outcomes. adequacy was defined as ratio total observed over recommended based on Institute Medicine body mass index-specific guidelines. Neonatal outcomes assessed were...
Abstract Background Appropriate gestational weight gain (GWG) is important for optimal pregnancy outcomes. This study prospectively evaluated the associations between GWG during second and third trimesters of adverse outcomes in an urban Tanzanian cohort. Methods We used data from a randomized clinical trial conducted among pregnant women recruited by 27 weeks gestation Dar es Salaam, Tanzania (N = 1230). Women’s was measured at baseline monthly antenatal visits. Weekly rate calculated...
Research Question Preterm birth (PTB) is the leading cause of perinatal mortality worldwide, with greatest burden occurring in resource-constrained settings. Based on hypothesis that altered placental angiogenesis and inflammation early pregnancy lead to PTB, we examined whether levels inflammatory angiogenic mediators, measured pregnancy, were predictive spontaneous PTB (sPTB). Study Design Plasma samples collected from a prospective cohort primigravid Tanzanian women between 12–27 weeks...
Abstract Background Malaria infection during pregnancy has negative health consequences for both mothers and offspring. Sub-microscopic malaria is common in most African countries. We sought to identify factors associated with sub-microscopic placental malaria, its association adverse outcomes among HIV-negative pregnant women Dar es Salaam, Tanzania. Methods recruited a cohort of their first trimester assessed the occurrence outcomes. The follow-up was done monthly from recruitment until...
Most existing research on gestational weight gain and pregnancy outcomes has not accounted for timing of gain. The area under the curve (AUC) provides a single measure that incorporates both total amount gained. This study evaluated predictors associated with second- third-trimester AUC from second third trimester using time-to-event analysis to account correlation between duration.Our prospective cohort used data LifeCodes at Brigham Women's Hospital. Maternal weights were available all...