A5101823145- Cardiovascular Function and Risk Factors
- Congenital Heart Disease Studies
- Cardiomyopathy and Myosin Studies
- Cardiovascular Issues in Pregnancy
- Congenital heart defects research
- Acute Myeloid Leukemia Research
- Urinary Bladder and Prostate Research
- Cardiac Imaging and Diagnostics
- Immune cells in cancer
- Cardiovascular Health and Disease Prevention
- Sexual function and dysfunction studies
- Adrenal Hormones and Disorders
- Hormonal and reproductive studies
- Anesthesia and Pain Management
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Coronary Artery Anomalies
- Estrogen and related hormone effects
- Williams Syndrome Research
- Hemodynamic Monitoring and Therapy
- Cancer Genomics and Diagnostics
- Blood Pressure and Hypertension Studies
- Chemotherapy-induced cardiotoxicity and mitigation
- Heart Failure Treatment and Management
- Adrenal and Paraganglionic Tumors
- Cardiovascular Effects of Exercise
Beijing Hospital
2020-2024
Shandong Provincial Hospital
2024
Shandong University
2024
Zhejiang University
2014-2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2012-2023
Sir Run Run Shaw Hospital
2014-2023
Institute of Hematology & Blood Diseases Hospital
2019-2022
Weatherford College
2021
Shandong University of Traditional Chinese Medicine
2021
China Medical University
2016
Risk stratification of young patients with hypertension remains challenging. Generally, machine learning (ML) is considered a promising alternative to traditional methods for clinical predictions because it capable processing large amounts complex data. We, therefore, explored the feasibility an ML approach predicting outcomes in and compared its performance that approaches now commonly used practice. Baseline data composite end point—comprising all-cause death, acute myocardial infarction,...
Introduction: Radiation-induced heart disease (RIHD) is a serious side effect of cancer treatment, including coronary artery disease, valvular cardiac dysfunction, cardiomyopathy, aortopathy, and chronic constrictive pericarditis. Herein, this case we present was diagnosed as radiation-induced pericarditis cardiomyopathy by means magnetic resonance (CMR) transthoracic echocardiogram, finally confirmed pathology after performing transplant operation. Conclusions: This supports notion that...
In the clinical practice, right ventricular (RV) manifestations have received less attention in hypertrophic cardiomyopathy (HCM). This paper aimed to evaluate risk prediction value and genetic characteristics of RV involvement HCM patients.A total 893 patients with were recruited. hypertrophy, obstruction, late gadolinium enhancement evaluated by echocardiography and/or cardiac magnetic resonance. Patients any above structural abnormalities identified as having involvement. All followed a...
<sec><strong>OBJECTIVE</strong> To determine the different clinical characteristics and outcomes of hypertrophic cardiomyopathy (HCM) patients with without hypertension (HT). </sec><sec><strong>METHODS</strong> A total 696 HCM were included in this study all diagnoses confirmed by genetic test. Patients analyzed separately septal reduction therapy (SRT) cohort non-SRT cohort. The primary endpoint was cardiovascular death secondary all-cause death. Outcome analyses conducted to evaluate...
Several fetal cardiovascular structural defects may alter the hemodynamics of cardiac chambers resulting in changes chamber sizes. Quantitative measurements sizes can augment diagnostic power echocardiography.Using a new left atrial volume tracking (LAVT) method, time-left curves (TLAVCs) be automatically obtained. The goal this study was to examine whether method used evaluate (LAV) and provide reference values for LAV indices function normal human fetuses.Two hundred four fetuses were...
Background: The presence of variants in OBSCN was identified to be linked hypertrophic cardiomyopathy (HCM), but whether truncating were associated with HCM remained unknown. Methods: Whole-exome sequencing performed 986 patients and 761 non-HCM controls search for variants, the result tested a replication cohort consisting 529 307 controls. association baseline characteristics prognosis ascertained. Results: There 28 qualifying gene detected 26 (2.6%) 6 (0.8%) more prevalent than (odds...
PRDM family proteins are dysregulated in many human diseases, especially hematological malignancies and solid cancers, share a unique N-terminal PR domain followed by zinc fingers toward the C terminus. With high frequency of DNA promoter hypermethylation, PRDM5 is primarily considered as tumor suppressor tumors. However, little known about function blood malignancies, acute myeloid leukemia (AML). In this study, we showed that expression levels were independently correlated with poor...
Fetal heart evaluation has been proven to have the utility in differential diagnosis of cardiomyopathies or prediction perinatal mortality congenital disease. The purpose this study is introduce a novel method that can measure global and regional longitudinal strain left ventricle fetuses, described as automated cardiac motion quantitation (aCMQ). Furthermore, evaluate feasibility value aCMQ.A cross-sectional was conducted 138 fetuses with normal structure, then were divided into four groups...
Following the gastrectomy, reduction in pulmonary function is partly attributed to postoperative pain. Subcostal quadratus lumborum block (QLB) has recently emerged as a promising component multimodal analgesia. We aimed assess impact of intermittent boluses subcostal QLB on recovery and analgesic efficacy after gastrectomy. Sixty patients scheduled for gastrectomy were randomly assigned either control group (multimodal analgesia) or intervention (intermittent plus analgesia). Two primary...
The relationship between thyroid diseases and cerebrovascular is getting increasingly attention. Studies have shown that are associated with many kinds of diseases, such as ischemic disease, moyamoya cerebral venous thrombosis, artery dissection. This article review the advances in research on correlation diseases. Key words: Cerebrovascular Disorders; Hypothyroidism; Hyperthyroidism; Autoantibodies; Thyroid Hormones; Risk Factors
Benign prostatic hyperplasia (BPH) is a non-malignant enlargement of the prostate gland that common in older men. The clinical manifestations BPH are frequent urination, urgency, incomplete dribbling urine, and urinary retention. Moxibustion, as convenient, safe effective method, has been widely applied treatment BPH. study aim to assess efficacy safety moxibustion for BPH.The following electronic databases will be searched regardless language publication status: Pubmed, MEDLINE, EMBASE,...
To investigate the effect of Rictor on hematopoiesis fetal liver by specific knock-out in hematopoietic cells Vav-Cre mice.E12.5 0.08ee from experimental group Vav-Cre; Rictorf/f embryos and control f/+ or were transplanted to recipients respectively observe reconstitution ability stem cells. In meantime, E14.5 0, 10, 20, 40, 60, 80 sorted Rictorf/+ analyze numbers functional after was knocked-out. Furthermore, self-renewal capacity investigated secondary transplantation BM primary that had...
Objective To measure mitral annular displacement (MAD) by conventional M-mode echocardiography and free angle echocardiographic measurements respectively in the normal second third trimester fetuses, to analyze differences between two methods explore correlation of MAD with gestational age routine parameters for evaluation fetal left ventricular function. Methods Totally 233 fetuses (GA) at 18 39 weeks were enrolled. was measured (MADCM) echocardiography(MADFM). Tissue Doppler imaging...
Myeloid cells have been identified as hematopoietic stem cell (HSC)-regulating cells. However, the mechanisms by which myeloid regulate function of HSCs are not fully defined. Our previous study indicated that over-expanded in Vav1-Cre;Rheb1 f l/fl mice. Here, using vivo and vitro models, we found Rheb1 -deficient neutrophils remodeled bone marrow environment induced expansion . Further studies showed loss impaired neutrophils’ ability to secrete IL-6, led mesenchymal (MSCs) produce more...
Objective To investigate the reliability of electrocardiographic (ECG) signal for accurate assessment myocardial ischemia in order to evaluate clinical value remote real-time ECG monitoring system based on GPRS patients with acute ST-elevation infarction (STEMI).Methods A total 60 STEMI admitted between April 2008 and December 2010 were enrolled.All subjects given routine 12 leads at same time.They divided into group group.The collects electrocardiosignal imitate V1,V3,V5 lead Ⅰ lead.P wave...