Kai Meng

ORCID: 0000-0002-2382-7161
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Research Areas
  • Animal Virus Infections Studies
  • Viral gastroenteritis research and epidemiology
  • Virus-based gene therapy research
  • Virology and Viral Diseases
  • Vector-borne infectious diseases
  • Viral Infections and Vectors
  • Wildlife Ecology and Conservation
  • Orbital Angular Momentum in Optics
  • Vector-Borne Animal Diseases
  • Genetic diversity and population structure
  • Identification and Quantification in Food
  • Ruminant Nutrition and Digestive Physiology
  • Microbial infections and disease research
  • Aquaculture disease management and microbiota
  • Genetic Mapping and Diversity in Plants and Animals
  • Plant-Microbe Interactions and Immunity
  • Advanced biosensing and bioanalysis techniques
  • Phytoestrogen effects and research
  • Respiratory viral infections research
  • Fatty Acid Research and Health
  • Indoor Air Quality and Microbial Exposure
  • Odor and Emission Control Technologies
  • interferon and immune responses
  • COVID-19 impact on air quality
  • Hepatitis Viruses Studies and Epidemiology

Shandong Academy of Agricultural Sciences
2018-2025

Affiliated Hospital of Shandong University of Traditional Chinese Medicine
2024

Shandong University of Traditional Chinese Medicine
2024

Poultry Research Institute
2019-2023

Inner Mongolia Agricultural University
2019

Shandong Agricultural University
2013-2017

Jiangsu Academy of Agricultural Sciences
2016

Taishan Medical University
2016

Shanghai Entry-Exit Inspection and Quarantine Bureau
2012

Anhui Normal University
2007-2009

Despite extensive vaccination efforts, certain pathogens continue to pose significant challenges the poultry industry. Interferons (IFNs) are crucial for innate immune defense against various pathogens. Chicken interferon-alpha (chIFN-α) reportedly has good inhibitory activity However, its production is often limited by low yields. This study aimed enhance of chIFN-α using an improved baculovirus expression system and evaluate antiviral efficacy both in vivo vitro. A recombinant bacmid...

10.1016/j.psj.2025.104870 article EN cc-by-nc-nd Poultry Science 2025-02-02

Since mid-2015, numerous outbreaks of hydropericardium-hepatitis syndrome (HHS), which is caused by a novel fowl adenovirus serotype 4 (FAdV-4), have been reported in chickens parts China, thereby causing huge economic losses to the poultry industry. Thus, an effective vaccine control further spread infections with this hyper-virulent FAdV-4 imperative. In study, we isolated strain SDJN0105 from broiler farm HHS disease Shandong Province. Pathogenicity was evaluated observation clinical...

10.3390/v11070627 article EN cc-by Viruses 2019-07-08

Fowl adenovirus (FAdV) is an infectious agent that can cause jaundice, severe anaemia, dyspnoea and reproductive disorders in fowls. Since 2015, FAdV disease has been rapidly spreading among broiler chickens China, where it caused significant economic losses. In this study, a loop-mediated isothermal amplification (LAMP) real-time turbidity method with strong specificity to was established.The established assay specific FAdV-4, the lower limit of detection 75 copies/μL extracted DNA. The...

10.1186/s12917-019-2015-5 article EN cc-by BMC Veterinary Research 2019-07-23

In 2017, a new type of goose-origin astrovirus (GoAstV) that is completely different from previously identified avian astroviruses (which have only 30.0% to 50.5% homology with GoAstV) has been isolated diseased geese in China. This disease can cause joint swelling sick geese, and the anatomy shows clear precipitation urate kidney. The rate death culling reach more than 30%, revealing disease's severe pathogenicity. To quickly accurately diagnose newly emerging disease, we established highly...

10.1128/msphere.00380-18 article EN cc-by mSphere 2018-11-06

Microbial aerosol whose species and concentrations are closely related to human health is ubiquitous. The effect of microbes on animal production performance is, in many cases, caused by the spreading air. Samples this experiment were from a live poultry market (LPM) Tai'an, China, collected three times day (8 am, 14 pm, 20 pm) over consecutive days each month for 11 months (Original sampling plan was year, government due environmental protection, LPM closed). main indicators test cultural...

10.3389/fmicb.2017.00551 article EN cc-by Frontiers in Microbiology 2017-03-30

AMA Wang J, Yang X, Y, et al. Experimental immunologyGenetic diversity and phylogenetic analysis of Tams1 Theileria annulata isolates from three continents between 2000 2012. Central European Journal Immunology. 2014;39(4):476-484. doi:10.5114/ceji.2014.47732. APA Wang, J., Yang, X., Y., Jing, Z., Meng, K., & Liu, J. (2014). Immunology, 39(4), 476-484. https://doi.org/10.5114/ceji.2014.47732 Chicago Jiayi, Xianyong Yuge Zhihong Kai Jianzhu Huimin Guo 2014. "Experimental 2012". Immunology 39...

10.5114/ceji.2014.47732 article EN cc-by-nc-nd Central European Journal of Immunology 2014-01-01

The objective of this study was to obtain insight into the adverse health effects airborne particulate matter (PM) collected from live bird markets (LBM) and determine whether biological material in PM accounts for immune-related inflammatory response. Mice were exposed a single or repeated dose PM, after which expression Toll-like receptors (TLRs), cytokines, chemokines lungs infected mice examined by enzyme-linked immunosorbent assay histopathological analysis. Results stimulation with...

10.3389/fimmu.2016.00252 article EN cc-by Frontiers in Immunology 2016-06-26

Abstract The identification of MHC class I–restricted CTL epitopes in certain species, particularly nonmammals, remains a challenge. In this study, we developed four-step scheme and confirmed its efficiency by identifying the Anpl-UAA*76–restricted Tembusu virus (TMUV) inbred haplotype ducks HBW/B4. First, peptide binding motif Anpl-UAA*76 was determined random library de novo liquid chromatography–tandem mass spectrometry, novel nonbiased, data-independent acquisition method that previously...

10.4049/jimmunol.2100382 article EN The Journal of Immunology 2022-07-01

Pigeon paramyxovirus type 1 (PPMV-1) is considered as an antigenic variant of Newcastle Disease leading to high mortality and significant economic losses the poultry industry. However, pathogenicity PPMV-1 chickens still unclear. Herein, we reported biological characterization isolated from diseased pigeons suspected studied its in SPF chickens. The phylogenetic tree evolution distances revealed that new isolate belonged a VI.2.1.1.2.2 sub-genotype NDV. Despite cleavage motif F protein...

10.24099/vet.arhiv.1862 article EN Veterinarski arhiv 2023-05-17

The black muntjac (Muntiacus crinifrons) is a vulnerable species found in the mountains of eastern China, about which little known. Here we develop 11 polymorphic microsatellite loci from (CA)(n) -enrichment library for animal. In analyses 25 individuals sampled, unbiased expected heterozygosity levels varied 0.686 to 0.876 and number alleles per locus five nine. Results that were highly indicated these markers are sufficiently powerful address such questions as parentage, mating system...

10.1111/j.1471-8286.2007.02003.x article EN Molecular Ecology Resources 2007-10-11

Abstract Eleven high polymorphic across-species loci were used to test the usefulness in individual identification and parentage determination of black muntjac detect genetic variation a captive population animal. Discrimination power for locus ranged from 0.845 0.949 with cumulative discrimination across eleven being up 1. The combined exclusion probability absence presence information on second parent was 0.999 1, respectively. These results indicated that microsatellites would be highly...

10.1163/157075609x454908 article EN Animal Biology 2009-01-01

Mainland serow is an endanged artiodactyl of southern Anhui province, China, that often subject to poaching. To provide easy, rapid and reliable marker for identification bushmeat, skin other tissues the species, we developed a sequence characterized amplified region (SCAR) based on species-specific random polymorphic DNA (RAPD) marker. Initially, 1012-bp fragment mainland was detected by RAPD primer S1193. Then, serow-specific pair (SCF/SCR) designed according specific fragment, resulting...

10.1111/j.1755-0998.2009.02526.x article EN Molecular Ecology Resources 2009-02-07

Avian paramyxovirus type 4 (APMV-4) has been frequently reported from wildfowl and waterfowl in recent year. However, few studies have on the molecular characteristics regional transmission of APMV-4, knowledge which is important for understanding genetic diversity epidemiology avian paramyxovirus. Herein, we report isolation one APMV-4 strain, designated as QY17, duck eastern China. The determined complete genome isolate with six gene segments 3′-N-P-M-F-HN-L-5′ was 15,054 nt length....

10.1111/tbed.13258 article EN Transboundary and Emerging Diseases 2019-05-27
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