A5102013589- Parasitic Infections and Diagnostics
- Plant Gene Expression Analysis
- Fungal Biology and Applications
- Microbial Natural Products and Biosynthesis
- Photosynthetic Processes and Mechanisms
- Malaria Research and Control
- Bryophyte Studies and Records
- Vector-borne infectious diseases
- Advanced Memory and Neural Computing
- Advanced Sensor and Energy Harvesting Materials
- Plant biochemistry and biosynthesis
- Nanoplatforms for cancer theranostics
- Nanoparticle-Based Drug Delivery
- RNA and protein synthesis mechanisms
- Protein Structure and Dynamics
- Prostate Cancer Treatment and Research
- Advances in Cucurbitaceae Research
- MicroRNA in disease regulation
- Conducting polymers and applications
- Nanomaterials and Printing Technologies
- Protein Degradation and Inhibitors
- NF-κB Signaling Pathways
- Enzyme Structure and Function
- Coccidia and coccidiosis research
- Photoacoustic and Ultrasonic Imaging
Universitat Pompeu Fabra
2018-2024
Yale University
2024
Binzhou University
2023
Binzhou Medical University
2023
Shandong University
2013-2022
Shandong University of Technology
2022
Dalian Medical University
2015-2021
First Affiliated Hospital of Dalian Medical University
2015-2021
University of Groningen
2019-2021
Zhengzhou University
2021
Abstract To realize high performance flexible transparent electronics with extreme environmental adaptivity, Ag nanowires (Ag NWs) electrodes should simultaneously meet the requirements of high-temperature tolerance, chemical and mechanical robustness. Herein, a scalable NWs bundle micro-meshes embedded in polyimide BMs/ePI) conducting film via facile spray coating transfer method is reported. Due to synergistic effect micromesh architecture, BMs/ePI electrode exhibits thermal stability (370...
High-density genetic map provides an essential framework for accurate and efficient genome assembly QTL fine mapping. Construction of high-density maps appears more feasible since the advent next-generation sequencing (NGS), which eases SNP discovery high-throughput genotyping large population. In this research, a high density cucumber (Cucumis sativus) was successfully constructed across F2 population by recently developed specific length amplified fragment (SLAF-seq) method. total, 18.69...
Designing a flexible transparent electronic device with biological functions is of great interest for the future wearable integrated artificial intelligence equipment. Nociceptor vitally important receptor sensory neuron, which responsible providing warning signal by recognizing noxious stimuli to reduce potential physical injury. Here, nociceptor demonstrated simulate based on indium tin oxide (ITO) memristor, exhibits forming-free and reproducible threshold resistive switching behaviors....
FNS I is a 2‐oxoglutarate dependent dioxygenase (2‐ODD) found mainly in species of the Apiaceae family. Here, an cDNA sequence was isolated from liverwort Plagiochasma appendiculatum (Aytoniaceae) and characterized. The recombinant protein exhibited high activity catalyzing conversion naringenin to apigenin 2‐hydroxynaringenin. critical residue for flavanone‐2‐hydroxylation Tyr240, as identified homology modeling site‐directed mutagenesis. also showed some flavonol synthase activity, it can...
The compatibility of free boronic acid building blocks in multicomponent reactions to readily create large libraries diverse and complex small molecules was investigated. Traditionally, synthesis is sequential, synthetically demanding, time-consuming, which leads high target times low coverage the chemical space. We have performed derivatives based on multiple chemistries using acoustic dispensing technology. a nanomole scale with success rates. discovery protease inhibitor underscores...
Background: Glioblastoma (GBM) is the most common and aggressive form of brain cancer. After surgery, radiotherapy mainstay treatment for GBM patients. Unfortunately, vast majority patients fail responding to because cells remain highly resistant radiation. Radiotherapy-induced DNA damage response may correlate with therapeutic resistance. Methods: Ionizing radiation (IR) was used induce damage. Cell proliferation migration were detected by wound-healing, MTT apoptosis assays....
Ribosomal protein s15a (RPS15A), a highly conserved cytoplasmic protein, promotes mRNA/ribosome interaction in translation. Recent evidence showed that RPS15A is essential for tumor growth. expression level was measured glioblastoma tissue samples and normal brain (NB) samples. RNAi stable cell line U87 U251 generated by the pLVTHM-GFP lentiviral system. The knockdown efficiency confirmed quantitative real-time PCR western blot. Molecular mechanisms effect of on growth migration were...
Abstract A 3D Co‐based metal–organic framework ( Co‐MOF ) with two kinds of large pores filled by free Co 2+ ions and ligands was synthesized characterized. To expand the MOF structure conductivity, were exchanged conductive ionic liquid EtpyBr photosensitive AgNO 3 through single crystal‐to‐single crystal transformation, which produced structure‐changed MOFs Co‐MOF‐Br Co‐Ag‐MOF , characterized single‐crystal X‐ray diffraction. Incorporating small quantities doped polyaniline (PANI) redox...
Leucocytozoon parasites infect a large number of avian hosts, including domestic chicken, and cause significant economical loss to the poultry industry. Although transmission stages were observed in blood cells more than century ago, specific host cell type(s) that gametocytes remain uncertain. Because all cells, red (RBCs), are nucleated, developing dramatically change morphology infected it has been difficult identify cell(s). Here we use cell-type antibodies investigate identities by...
Apigenin, a widely distributed flavone, exhibits excellent antioxidant, anti-inflammatory, and antitumor properties. In addition, the methylation of apigenin is generally considered to result in better absorption greatly increased bioavailability. Here, four putative Class II methyltransferase genes were identified from transcriptome sequences generated liverwort species Plagiochasma appendiculatum. Each was heterologously expressed as His-fusion protein Escherichia coli their activity...
The rodent malaria parasite Plasmodium yoelii is an important animal model for studying host-parasite interaction and molecular basis of pathogenesis. Although a draft genome P. YM available, RNA sequencing (RNA-seq) data several species (RMP) were reported recently, variations in coding regions structure mRNA transcript are likely present between different strains or subspecies. Sequencing cDNA libraries from additional strains/subspecies will help improve the gene models annotation. Here...
Novel biophysical tools allow the structural dynamics of proteins and regulation such by binding partners to be explored in unprecedented detail. Although this has provided critical insights into protein function, means which direct evolution remain poorly understood. Here, we investigated how with a bilobed structure, composed two related domains from periplasmic-binding protein-like II domain family, have undergone divergent evolution, leading adaptation their dynamics. We performed...
High-performance electrical heaters with a rapid thermal response, homogeneous temperature distribution, and chemical mechanical robustness are desirable for inevitable use in various areas such as defrosting windows wearable thermotherapy. Herein, optimally engineered ordered Ag nanowire micromeshes partially embedded poly(ethylene terephthalate) matrix (Ag NMs/ePET) via facile spray coating transfer approach flexible transparent conductor heater applications, which exhibit slight sheet...
Abstract Background Malignant melanoma is an aggressive skin cancer and a tumor of melanocytic origin. Recent studies have suggested that long non-coding RNAs (lncRNAs) play crucial regulatory roles in multiple malignancies, including melanoma. Testis expressed 41 (TEX41) relatively new lncRNA whose mechanism remains vague. Aims This study aimed to explore the role specific TEX41 Methods The expression genes involved this was determined by qRT-PCR. Functional assays were conducted analyze...
Leucocytozoon parasites infect many species of avian hosts, including domestic chicken, and can inflict heavy economic loss on the poultry industry. Two major have been reported in China, L. sabrazesi caulleryi, although appears to be more widespread than caulleryi southern China. The traditional method for detecting infection is microscopic examination blood smears presence mature gametocytes circulation, which may miss infections with low parasitemia (gametocytemia) or immature...
AMA Wang J, Yang X, Y, et al. Experimental immunologyGenetic diversity and phylogenetic analysis of Tams1 Theileria annulata isolates from three continents between 2000 2012. Central European Journal Immunology. 2014;39(4):476-484. doi:10.5114/ceji.2014.47732. APA Wang, J., Yang, X., Y., Jing, Z., Meng, K., & Liu, J. (2014). Immunology, 39(4), 476-484. https://doi.org/10.5114/ceji.2014.47732 Chicago Jiayi, Xianyong Yuge Zhihong Kai Jianzhu Huimin Guo 2014. "Experimental 2012". Immunology 39...
CRISPR/Cas9 is a powerful genome editing method that has greatly facilitated functional studies in many eukaryotic organisms including malaria parasites. Due to the lack of genes encoding enzymes necessary for non-homologous end joining DNA repair pathway, genetic manipulation parasite genomes generally accomplished through homologous recombination requiring presence templates. Recently, an alternative double-strand break microhomology-mediated joining, was found Plasmodium falciparum...
The search for decent material systems is the most desirable to obtain superior performances in resistive random access memory (RRAM) devices. Nitride switching materials have attracted much attention RRAMs due their excellent device properties such as high-speed and low-energy switching. However, unclear mechanisms, which been characterized only indirectly, are a critical problem continued RRAM optimization, especially transparent devices with indium tin oxide (ITO) electrodes. Here, we...
Abstract Transparent nonvolatile memory fabricated on flexible substrates is expected to meet the requirement of integrated transparent circuits. Here, a simple route prepare memristors presented. Flexible conducting Ag grids with low sheet resistance are self‐assembled polyethylene terephthalate (PET) substrate, and WO 3 dielectric layer selectively deposited via low‐cost cathodic electrodeposition method under ambient condition. Finally, Au/WO /Ag grids/PET device exhibits fair good...