- Gastric Cancer Management and Outcomes
- Microbial Natural Products and Biosynthesis
- Cancer Mechanisms and Therapy
- Adipose Tissue and Metabolism
- Metabolism and Genetic Disorders
- Folate and B Vitamins Research
- Liver Disease Diagnosis and Treatment
- Cholesterol and Lipid Metabolism
- Intracerebral and Subarachnoid Hemorrhage Research
- Mental Health Research Topics
- Reproductive System and Pregnancy
- Cytokine Signaling Pathways and Interactions
- Diet and metabolism studies
- Nutritional Studies and Diet
- Cardiovascular Health and Risk Factors
- Neurosurgical Procedures and Complications
- Autoimmune and Inflammatory Disorders Research
- Kruppel-like factors research
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Traditional Chinese Medicine Studies
- Antimicrobial Peptides and Activities
- Cancer, Hypoxia, and Metabolism
- Skin Protection and Aging
- Drug Transport and Resistance Mechanisms
- Ocular Oncology and Treatments
Baoding People's Hospital
2023-2024
Baoding No.1 Central Hospital
2023-2024
Affiliated Hospital of Southwest Medical University
2022-2023
Wuhou District People's Hospital, Chengdu
2023
Cangzhou Central Hospital
2021-2022
Academy of Military Medical Sciences
2012-2022
The University of Texas Southwestern Medical Center
2020
Southwestern Medical Center
2020
Henan University of Science and Technology
2016-2019
Tongji Hospital
2012-2014
Abstract Background Non-alcoholic fatty liver disease (NAFLD) is characterized by excessive lipid accumulation in the liver. Riboflavin, one of water soluble vitamins, plays a role metabolism and antioxidant function. However, effects riboflavin deficiency on NAFLD development have not yet to be fully explored. Methods In present study, an animal model was induced high fat diet feeding mice cellular developed HepG2 cells palmitic acid (PA) exposure. The function were investigated both vivo...
Resilience is a protective feature against anxiety and depression disorders. However, the precise relationship structure of resilience remain poorly understood. This study sought to investigate link among resilience' components as well depression. 1,279 clinical nurses were recruited. 10-item Connor-Davidson Scale, Generalized Anxiety Disorder 7, Patient Health Questionnaire 9 employed evaluate resilience, anxiety, depression, respectively. The regularized partial-correlation network was...
Intracerebral hemorrhage (ICH) is a devastating event with high disability and fatality rates. However, there lack of effective treatments for this condition. We aimed to investigate the neuroprotective axonal regenerative effects progesterone after ICH. For purpose, an ICH model was established in adult mice by injecting type VII collagenase into striatum; were then treated (8 mg/kg). Hematoma absorption, neurological scores, brain water content evaluated on days one, three, seven The...
Purpose: To examine whether exercise self-efficacy mediates the contributions of pain catastrophizing and kinesiophobia to adherence in patients after total knee arthroplasty. Patients Methods: A cross-sectional study design was conducted. 211 post-total arthroplasty were recruited from three orthopedics units a tertiary hospital China. Participants invited complete questionnaires on catastrophizing, kinesiophobia, self-efficacy, adherence. Mplus 8.3 software used construct mediation models....
Quercetin has been demonstrated to be effective in increasing physical endurance mice and humans. However, the mechanisms involved are not fully understood. In this study, male Kunming were fed a diet containing 0.1% quercetin for 14 days before swimming 60 min. The overall serum metabolic profile was investigated by ¹H nuclear magnetic resonance-based metabolomic approach. Serum glucose, lactate, nonesterified fatty acids (NEFA), nonprotein nitrogen (NPN), as well hepatic muscular glycogen...
Kinesiophobia is common in patients after total knee arthroplasty and an important risk factor for post-operative recovery outcomes. Little known about the complex intercorrelations between different components of pain catastrophizing, self-efficacy, kinesiophobia. This study aimed to identify central kinesiophobia explore interconnectedness
The present study was designed to investigate the efficacy and mechanism of acupuncture treatment on embryo implantation failure in rats. pregnant rats were randomized into normal group (N), (M), (A), progestin (W). model established by mifepristone. Efficacy evaluated number implanted embryos. expression CCL2 CXCL8 subset uterine natural killer cells endometrium detected. We demonstrated that embryos dramatically reduced after mifepristone (M group) treatment, while (A (W treatments...
This study was aimed at investigating the effects of quercetin on mRNA expression and activity critical enzymes in homocysteine metabolism rats fed a methionine-enriched diet. Rats were for 6 weeks following diets, that is, control, 0.5% quercetin, 1.0% methionine, methionine plus diets. Serum significantly increased after treatment decreased addition quercetin. The synthase or supplementation, while its enzymatic supplementation. cystathionine β -synthase γ -lyase upregulated more...
Abstract Background Growth hormone (GH) and insulin signaling pathways are known important regulators of adipose homeostasis. The cross-talk between GH in mature adipocytes is poorly understood. Methods In the present study, impact on GH-mediated differentiated 3T3-F442A primary mice was examined. Results Insulin alone did not induce STAT5 tyrosine phosphorylation, but enhanced GH-induced activation. This effect more pronounced when added 20 min prior to treatment. above results were further...
This study was aimed to observe the effects of vitamin B 1 , 2 and niacin supplementation on hepatic gene expression profiles in mice exposed acute hypoxia. Thirty were randomly divided into normal, hypoxia, hypoxia plus groups fed corresponding diets for weeks then a simulated altitude 6000 m 8 h. Hepatic analyzed using microarray technique. Several biochemical markers also assayed. The results showed that total 2476 genes expressed differentially after exposure (1508 upregulated 968...
Objective. To investigate the clinical efficacy and safety of bevacizumab, apatinib, recombinant human endothelial inhibitor in treatment advanced gastric cancer. Methods. The medical data 204 patients with a medium to cancer assessed for eligibility treated our hospital from February 2019 April 2020 were retrospectively analyzed. eligible assigned at ratio 1 : 1:1 either control group (chemotherapy), study I (bevacizumab combined chemotherapy), II (apatinib or III (recombinant chemotherapy)...