A5101511961- Sleep and related disorders
- Plant Molecular Biology Research
- Research in Cotton Cultivation
- Sleep and Wakefulness Research
- Greenhouse Technology and Climate Control
- Plant Physiology and Cultivation Studies
- Cell Adhesion Molecules Research
- Signaling Pathways in Disease
- Agricultural Science and Fertilization
- Chemokine receptors and signaling
- Lipid metabolism and biosynthesis
- Advanced Cellulose Research Studies
- Immunotherapy and Immune Responses
- Cellular transport and secretion
- Cancer-related Molecular Pathways
- Aortic Disease and Treatment Approaches
- Diverse Educational Innovations Studies
- Food Science and Nutritional Studies
- Microtubule and mitosis dynamics
- Chemotherapy-induced cardiotoxicity and mitigation
- Cardiac Ischemia and Reperfusion
- Garlic and Onion Studies
- Pancreatic function and diabetes
- PI3K/AKT/mTOR signaling in cancer
- Metal complexes synthesis and properties
Southwest University
2024-2025
Henan Provincial People's Hospital
2021
Henan University
2021
Zhengzhou University
2021
Beijing Children’s Hospital
2018
Capital Medical University
2018
Fu Wai Hospital
2017
Chinese Academy of Medical Sciences & Peking Union Medical College
2014-2015
Air Force Medical University
2013-2014
First Affiliated Hospital of Zhengzhou University
2014
Cotton is the most important natural fiber crop in world. cells are not only major economic product of cotton, but also an ideal material for studying growth and development plant cell. The cell elongation secondary wall short thick mutant ligon lintless-1 (li-1) severely impaired. However, its mechanism still unclear. Boosting evidence showed that sphingolipids sterols play roles But it unknown changes these lipids li-1 cells. In study, we detected lipid profiles 10-DPA 20-DPA wild type...
Boosting evidence indicated lipids play important roles in plants. To explore lipid function cotton fiber development, the composition and content were detected by untargeted targeted lipidomics. Compared with rapid elongation fibers, intensity of 16 sub-classes 56 molecular species decreased, while only 7 26 increased fibers at stage secondary cell wall deposition. Unexpectedly, stage, 20 60 significantly, 5 8 decreased ligon lintless-1 (li-1) mutant compared its wild-type Texas Maker-1...
Ovarian cancer is an aggressive gynecological malignancy with high metastatic potential. Recently, the CXC receptor (CXCR7) has been identified as a new for stromal-derived factor-1 (SDF-1), and exerts important roles in development. However, its effect on ovarian underlying mechanism remain unknown. In this study, we detected abundant CXCR7 expression tissues cells. Moreover, SDF-1 induced dramatically upregulation of mRNA protein levels, indicating that SDF-1/CXCR7 axis existed cancer....
To explore the characteristics of gut microbiota and its relationship between clinical manifestations in patients with type 1 narcolepsy (NT1).Scale polysomnography were performed 20 NT1 16 healthy controls (HC group) to evaluate NT1. Illumina sequencing was on bacterial 16S ribosomal RNA gene using V3-V4 regions compare fecal all subjects. Associations analyzed partial correlation analysis.Compared HC group, group had a significantly higher ESS score, longer total sleep time, increased...
Sphingolipids serve as essential components of biomembrane and possess significant bioactive properties. Sphingosine-1-phophate (S1P) plays a key role in plant resistance to stress, but its specific impact on growth development remains be fully elucidated. Cotton fiber cells are an ideal material for investigating the maturation cells. In this study, we examined content composition sphingosine (Sph) S1P throughout progression cell development. The elevated gradually during elongation...
ABSTRACT Although the cell membrane and cytoskeleton play essential roles in cellular morphogenesis, interaction between is poorly understood. Cotton fibers are extremely elongated single cells, which makes them an ideal model for studying development. Here, we used sphingolipid biosynthesis inhibitor, fumonisin B1 (FB1), found that it effectively suppressed myeloblastosis (MYB) transcription factor GhMYB86, thereby negatively affecting fiber elongation. A direct target of GhMYB86 GhTUB7 ,...
Acute statin treatment has been reported to be critical in protecting the cardiac cells against ischemia/reperfusion injury by activating PI3K/Akt signal pathway. In vitro rat myocardial model, chronic led upregulation of phosphatase and tensin homolog (PTEN). This potentially indicated correlation PTEN protective effect on myocardium. this current study, we evaluated role sodium orthovanadate a nonspecific inhibitor its with atorvastatin myocardium injury. We found long-term could increase...
// Tao Sun 1 , Hong-Ju Zhang 2 Chayakrit Krittanawong 3 Su Wang Ying Zhao Li Qiancheng Yin Donghua Qian Ji Huang Jingmei Zhizhong and Yutong Cheng Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China Division Ultrasound, Fu Wai National Center for Cardiovascular Diseases, Internal Medicine, Icahn School Medicine at Mount Sinai St. Luke's West, New York, NY, USA Correspondence to: Cheng, email: stzhjszcn@163.com Keywords: ischemic postconditioning,...
Objective To explore the clinical, imaging, genetic features in a case of fatal familial insomnia (FFI), and review related literatures. Methods A middle-aged woman diagnosed as frontotemporal dementia based on preliminary manifestation abnormal mental behavior was reported. The clinical features, imaging characteristics, electroencephalogram polysomnogram patient were analyzed, blood samples from some her members collected for sequencing prion protein gene (PRNP). Results This...
Objective: To investigate the association between orexin-2 receptor (OX2R) gene polymorphisms and Alzheimer's disease (AD). Methods: A total of 350 patients with AD diagnosed at People's Hospital Zhengzhou University from January 2014 to 2018 were enrolled as case group, healthy subjects selected control their general demographic data collected. The peripheral blood samples collected for DNA extraction, 6 loci in OX2R two groups detected by polymerase chain reaction (PCR) sequencing....
Objective To investigate cognitive impairment mechanism by studying dorsolateral prefrontal cortex connectivity in patients with primary insomnia. Methods Forty insomnia and 50 healthy subjects from the Department of Neurology, People’s Hospital Zhengzhou University during period April 2011 through 2013 were included. The World Health Organization-University California Los Angeles Auditory Verbal Learning Test (WHO-UCLA AVLT) digital pin test applied to evaluate subjects’ word study...