Tao Sun

ORCID: 0000-0002-5504-1817
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About
Contact & Profiles
Research Areas
  • Cardiac Imaging and Diagnostics
  • Glioma Diagnosis and Treatment
  • Coronary Interventions and Diagnostics
  • Cardiovascular Function and Risk Factors
  • Bone health and treatments
  • Bone health and osteoporosis research
  • Meningioma and schwannoma management
  • Radiomics and Machine Learning in Medical Imaging
  • Cardiac Structural Anomalies and Repair
  • Cardiac and Coronary Surgery Techniques
  • Orthopaedic implants and arthroplasty
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Cardiovascular Health and Disease Prevention
  • Heart Rate Variability and Autonomic Control
  • Cardiac Valve Diseases and Treatments
  • Cardiac Fibrosis and Remodeling
  • Nutritional Studies and Diet
  • Cardiovascular Issues in Pregnancy
  • Bone Metabolism and Diseases
  • Circular RNAs in diseases
  • Cardiomyopathy and Myosin Studies
  • Acute Myocardial Infarction Research
  • Adipokines, Inflammation, and Metabolic Diseases
  • COVID-19 Clinical Research Studies
  • Cardiac Health and Mental Health

Guangdong Academy of Medical Sciences
2025

Guangdong Provincial People's Hospital
2025

Jiangsu University
2014-2024

Wenzhou Medical University
2015-2024

Affiliated Hospital of Jiangsu University
2014-2024

Lishui Central Hospital
2019-2024

Beijing Tian Tan Hospital
2012-2023

Capital Medical University
2012-2023

Beijing Anzhen Hospital
2010-2023

Zhejiang University
2023

Brainstem gliomas are a heterogeneous group of tumors that encompass both benign cured with surgical resection and highly lethal cancers no efficacious therapies. We perform comprehensive study incorporating epigenetic genomic analyses on large cohort brainstem gliomas, including Diffuse Intrinsic Pontine Gliomas. Here we report, from DNA methylation data, distinct clusters termed H3-Pons, H3-Medulla, IDH, PA-like, each associated unique clinical profiles. The majority within H3-Pons...

10.1038/s41467-020-16682-y article EN cc-by Nature Communications 2020-06-17

Abstract We investigated whether the activation of astroglial group II and III metabotropic glutamate receptors (mGluRs) could exert neuroprotective effects neuroprotection was related to uptake. Our results showed that or mGluRs exerted against 1‐methyl‐4‐phenylpyridinium (MPP + ) conditioned medium‐induced neurotoxicity in midbrain neuron cultures. Furthermore, MPP decreased uptake primary astrocytes C6 glioma cells, which recovered by activating mGluRs. Specific antagonists completely...

10.1111/j.1471-4159.2004.02937.x article EN Journal of Neurochemistry 2005-01-26

Background Lung cancer is one of the most common forms resulting in over a million deaths per year worldwide. Typically, problem can be approached by developing more discriminative diagnosis methods. In this paper, computer-aided was used to facilitate prediction characteristics solitary pulmonary nodules CT lungs diagnose early-stage lung cancer. Methods The synthetic minority over-sampling technique (SMOTE) account for raw data order balance original training set. Curvelet-transformation...

10.1371/journal.pone.0063559 article EN cc-by PLoS ONE 2013-05-15

Previous studies have demonstrated the effect of human parathyroid hormone (1–34) (PTH) or strontium-doped hydroxyapatite coating (Sr-HA) on osteoporotic bone implantation. However, reports about effects PTH plus Sr-HA osseointegration titanium implants in a state osteoporosis were limited. This study was designed to investigate intermittent administration implant fixation ovariectomized (OVX) rats. Twelve weeks after bilateral ovariectomy, all animals randomly divided into four groups...

10.1177/0885328215610898 article EN Journal of Biomaterials Applications 2015-10-18

OBJECTIVE Diffusion tensor imaging (DTI) and diffusion tractography (DTT) have the ability to noninvasively visualize changes in white matter tracts, as well their relationships with lesions other structures. DTI/DTT has been increasingly used improve safety results of surgical treatment for eloquent areas, such brainstem cavernous malformations. This study aimed investigate application value glioma surgery validate spatial accuracy reconstructed corticospinal tracts (CSTs). METHODS A...

10.3171/2020.10.focus20166 article EN Neurosurgical FOCUS 2021-01-01

The study compared downstream coronary and conduit disease progression in the left anterior descending artery treated with bypass grafting using internal mammary (LIMA) versus percutaneous intervention bare metal stent (BMS) or drug eluting (DES).A total of 12 301 consecutive patients underwent isolated primary revascularization, which 2386 met our inclusion criteria (Percutaneous intervention, n=1450; grafting, n=936). Propensity score analysis matched 628 patients, 468 were to LIMA...

10.1161/jaha.116.003568 article EN cc-by-nc-nd Journal of the American Heart Association 2016-09-01

The objective of this study was to evaluate local bone formation following systemic administration parathyroid hormone (1-34), a surgically implanted synthetic β-tricalcium phosphate biomaterial serving as matrix support new formation. Twelve weeks after bilateral ovariectomy, all rats underwent defect in the distal femurs, and into critical sized defects. After operation, animals were randomly divided four groups received subcutaneous injections until death at eight weeks: sham (group ST);...

10.1177/0885328215592854 article EN Journal of Biomaterials Applications 2015-06-26

We aimed to investigate whether left ventricular (LV) twist analysis can detect the extent of myocardial fibrosis in patients with hypertrophic cardiomyopathy (HCM). This prospective case-control study recruited 81 consecutive HCM examined between January 2012 and April 2013. Data 76 were analyzed after excluding 5 whose echocardiographic images poor quality. Healthy volunteers (n = 46) served as controls. Both groups underwent comprehensive examination (i.e., Bas-Rotation, AP-Rotation,...

10.1007/s10554-014-0509-6 article EN cc-by The International Journal of Cardiovascular Imaging 2014-08-08
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