Reza J. Mehran

ORCID: 0000-0002-2557-2000
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About
Contact & Profiles
Research Areas
  • Lung Cancer Diagnosis and Treatment
  • Lung Cancer Treatments and Mutations
  • Esophageal Cancer Research and Treatment
  • Gastric Cancer Management and Outcomes
  • Occupational and environmental lung diseases
  • Pleural and Pulmonary Diseases
  • Esophageal and GI Pathology
  • Cancer Immunotherapy and Biomarkers
  • Medical Imaging and Pathology Studies
  • Pancreatic and Hepatic Oncology Research
  • Lung Cancer Research Studies
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Cardiac, Anesthesia and Surgical Outcomes
  • Cancer Genomics and Diagnostics
  • Radiomics and Machine Learning in Medical Imaging
  • Tracheal and airway disorders
  • Cancer Research and Treatments
  • Anesthesia and Pain Management
  • Colorectal Cancer Treatments and Studies
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Enhanced Recovery After Surgery
  • Radiopharmaceutical Chemistry and Applications
  • Advanced Radiotherapy Techniques
  • Angiogenesis and VEGF in Cancer
  • Sarcoma Diagnosis and Treatment

The University of Texas MD Anderson Cancer Center
2016-2025

Yahoo (United Kingdom)
2023-2024

RELX Group (United States)
2024

Faculty of 1000 (United States)
2024

University of Tampa
2024

New York Proton Center
2024

AstraZeneca (Canada)
2023

Sanofi (France)
2023

Chugai Pharma (United States)
2023

Boehringer Ingelheim (Australia)
2023

Whether dosimetric advantages of proton beam therapy (PBT) translate to improved clinical outcomes compared with intensity-modulated radiation (IMRT) remains unclear. This randomized trial total toxicity burden (TTB) and progression-free survival (PFS) between these modalities for esophageal cancer.This phase IIB randomly assigned patients PBT or IMRT (50.4 Gy), stratified histology, resectability, induction chemotherapy, stage. The prespecified coprimary end points were TTB PFS. TTB, a...

10.1200/jco.19.02503 article EN Journal of Clinical Oncology 2020-03-11

Abstract Neoadjuvant ipilimumab + nivolumab (Ipi+Nivo) and chemotherapy (Nivo+CT) induce greater pathologic response rates than CT alone in patients with operable non-small cell lung cancer (NSCLC). The impact of adding to neoadjuvant Nivo+CT is unknown. Here we report the results correlates two arms phase 2 platform NEOSTAR trial testing Ipi+Nivo+CT major (MPR) as primary endpoint. MPR were 32.1% (7/22, 80% confidence interval (CI) 18.7–43.1%) arm 50% (11/22, CI 34.6–61.1%) arm; endpoint...

10.1038/s41591-022-02189-0 article EN cc-by Nature Medicine 2023-03-01

To determine the frequency of estrogen receptor alpha and beta progesterone protein immunohistochemical expression in a large set non-small cell lung carcinoma (NSCLC) specimens to compare our results with those for some same antibodies that have provided inconsistent previously published reports.Using multiple antibodies, we investigated receptors 317 NSCLCs placed tissue microarrays correlated their patients' clinicopathologic characteristics adenocarcinomas EGFR mutation status.Estrogen...

10.1158/1078-0432.ccr-09-0033 article EN Clinical Cancer Research 2009-08-26

The authors evaluated the efficacy, patterns of failure, and toxicity stereotactic ablative radiotherapy (SABR) for patients with medically inoperable, clinical stage I non-small cell lung cancer (NSCLC) in a prospective trial 7 years follow-up. Clinical staging was performed according to seventh edition American Joint Committee on Cancer TNM system.Eligible histologically confirmed NSCLC as determined using positron emission tomography were treated SABR (50 grays 4 fractions). primary...

10.1002/cncr.30693 article EN Cancer 2017-03-27

Stereotactic ablative radiotherapy (SABR) can achieve excellent local control rates in early-stage non-small cell lung cancer (NSCLC) and has emerged as a standard treatment option for patients who cannot undergo surgery or those with isolated recurrences. However, factors that may predict toxicity survival are largely unknown. We sought here to identify predictors of pneumonitis after SABR NSCLC relatively large single-institution series. Subjects were 130 stage I treated four-dimensional...

10.1186/1748-717x-7-152 article EN cc-by Radiation Oncology 2012-09-10

// Hongyu Li 1, 4 , Jing Hu 1 Shuhong Wu Wang Xiaobo Cao Xiaoshan Zhang Bingbing Dai Mengru Ruping Shao Ran Mourad Majidi Lin Ji John V. Heymach 2 Michael 3 Shiyang Pan 5 Minna 6 Reza J. Mehran Stephen G. Swisher Jack A. Roth and Bingliang Fang Department of Thoracic Cardiovascular Surgery, University Texas MD Anderson Cancer Center, Houston, Texas, USA Thoracic/Head & Neck Medical Oncology, Lymphoma, Jilin Province Hospital, Changchun, Jilin, China Laboratory Medicine, The First...

10.18632/oncotarget.6516 article EN Oncotarget 2015-12-09

A planar waveguide model with a frequency-dependent effective relative permittivity and width is developed for the open microstrip line. The validity of this shown by experimental results from measurements resonator sliding-load technique.

10.1049/el:19750352 article EN Electronics Letters 1975-09-18

Previous literature has reported lower morbidity for video-assisted thoracoscopic surgery lobectomy (VL) compared with open (OL); however, most comparative studies have been retrospective and failed to compare well-matched patient groups, therefore allowing selection bias influence results. Furthermore, oncological adequacy of VL recently questioned, particularly respect lymphadenectomy. This study aimed evaluate short- long-term outcomes a large cohort consecutive patients c-stage I...

10.1093/ejcts/ezu036 article EN European Journal of Cardio-Thoracic Surgery 2014-03-05

In lung cancer, outcome measurement has been mostly limited to survival. Proper assessment of the value cancer treatments, and performance institutions delivering care, requires more comprehensive standardised outcomes.The International Consortium for Health Outcomes Measurement convened an international, multidisciplinary working group patient representatives, medical oncologists, surgeons, radiation pulmonologists, palliative care specialists, registry experts specialist nurses review...

10.1183/13993003.02049-2015 article EN cc-by-nc European Respiratory Journal 2016-07-07

Purpose Small observational studies have shown a survival advantage to undergoing cancer-directed surgery for malignant pleural mesothelioma (MPM); however, it is unclear if these results are generalizable. Our purpose was evaluate after treatment of MPM with and explore the effect interaction chemotherapy or radiation therapy on by using National Cancer Database. Patients Methods microscopically proven were identified within Database (2004 2014). Propensity score matching performed 1:2...

10.1200/jco.2017.73.8401 article EN Journal of Clinical Oncology 2017-08-17
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