A5056185806- Nutrition and Health in Aging
- MicroRNA in disease regulation
- Clinical Nutrition and Gastroenterology
- Extracellular vesicles in disease
- Pharmaceutical studies and practices
- Optimism, Hope, and Well-being
- Pancreatic and Hepatic Oncology Research
- Frailty in Older Adults
- Chronic Lymphocytic Leukemia Research
- Palliative Care and End-of-Life Issues
- Dendrimers and Hyperbranched Polymers
- Medical History and Innovations
- Cancer survivorship and care
- Nanoparticle-Based Drug Delivery
- Nanoplatforms for cancer theranostics
- Genetic factors in colorectal cancer
- Neurological Disease Mechanisms and Treatments
- Respiratory and Cough-Related Research
- PI3K/AKT/mTOR signaling in cancer
- Circular RNAs in diseases
- Flavonoids in Medical Research
- Pediatric health and respiratory diseases
- Cancer Cells and Metastasis
- HER2/EGFR in Cancer Research
- Digital Imaging in Medicine
Chinese Academy of Medical Sciences & Peking Union Medical College
2017-2022
National Cancer Center
2018
Beijing Hospital
2017
Background. Identifying diagnostic and prognostic biomarkers that could be targeted in the therapy of pancreatic cancer is essential. Objective. Investigations were conducted with respect to plasma miRNA (miR-21, miR-210, miR-155, miR-196a, miR-20a, miR-25) expression clinicopathologic factors evaluate value miRNAs ductal adenocarcinoma (PDAC). Methods. Plasma detected by real-time quantitative PCR, association was subsequently performed univariate multivariate analyses. Results. Six...
Aims Prevalence of malnutrition is a common and serious issue responsible for the morbidity mortality rate among hospitalized patients. We aimed to provide an actual comprehensive situation nutritional characteristics, support risk factors patients in China. Methods analyzed data from nutritionDay audit 2016 The international daylong cross-sectional survey was performed on November 10th, via filling out several questionnaires regarding information patients' illness, food intake history,...
Colorectal cancer patients with diabetes had the high risks of total mortality. High expression MSX2 is related to development diabetes. There are few reports about clinical implications and function in colorectal (CRC). The purpose this study investigate relationship between relevance discover possible mechanism CRC. Compared adjacent tissues, was higher tumor tissues both mRNA protein levels (<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"...
ABSTRACT Background In China, caregiving for cancer patients is primarily the responsibility of family members. This role often exposes caregivers to contemplation mortality. Death anxiety among may influence care they offer patients. Objective study aims evaluate prevailing level death Chinese and identify its influencing factors. Design cross‐sectional followed STROBE statement. Methods A total 220 were recruited from a prominent tertiary hospital in southern China. The survey included...
On the increasing prevalence of using mAbs (monoclonal antibodies) in cancer therapy and severe risk hyperglycemia, we aimed to analyze main clinical ADRs mAbs, with a focus on adverse hyperglycemic events associated currently clinically used mAbs. as well target information were selected from Martinadale book published articles. Drug approving was collected each government website, ADR statistic data VigibaseR, comparing Adverse Event Reporting System US FDA. Top 10 classified within...
Nanodrug self-assembled by amphiphilic small molecules were proved to be important resource of medicine. In this study, a nanodrug hydrophobic doxorubicin (DOX)linked lactose (Lac) via pH sensitive acylhydrazide bond was used as carrier entrap the form drug-loaded nanoparticles (Lac-DOX/DOX). We hope increased drug ligand ratio will improve targeting efficiency nanodrug, which leads better toxicity. The in vitro and vivo experiments that with Lac-DOX/DOX, we achieved active targeting,...
NutritionDay is a yearly global point-prevalence study of malnutrition or nutritional risk in hospitals. We aimed to provide comprehensive survey hospitalized patients and analyze the factors prolonged hospitalization Chinese inpatients.The international daylong cross-sectional was performed on November 07th, 2019. Ten hospitals were invited participate this survey. Nutritional identified by screening 2002, ESPEN criteria. measured incidence risk. And we analysed for length stay patients.875...
目的 探讨微信健康教育模式对中青年2型糖尿病患者行为进行干预的效果。 方法 选择120例中青年2型糖尿病患者，根据随机数字表法将患者分为对照组和干预组，每组60例。对照组在住院期间的接受常规糖尿病知识教育和护理，干预组在对照组的基础上，出院以后通过微信好友或微信群进一步进行认知、行为干预，比较干预前、干预6个月和12个月时两组患者空腹血糖、餐后2 h血糖、糖化血红蛋白(HbA1c)和自我管理水平各项指标的变化。 结果 与干预前相比，干预组和对照组在干预后6个月、12个月的空腹血糖下降(t＝8.456、10.615、5.574、6.711，均P<0.01)，餐后2 h血糖降低(t＝13.925、18.694、11.212、12.495，均P<0.01)，HbAlc(t＝10.577、13.408、3.294、5.377，均P<0.01)均显著下降；干预组在6个月、12个月的空腹血糖、餐后2...