A5100425487- Clinical Nutrition and Gastroenterology
- Nutrition and Health in Aging
- Enhanced Recovery After Surgery
- Abdominal Surgery and Complications
- Electrolyte and hormonal disorders
- Liver Disease and Transplantation
- Marine Sponges and Natural Products
- Diet and metabolism studies
- Microbial Natural Products and Biosynthesis
- Frailty in Older Adults
- Child Nutrition and Feeding Issues
- Esophageal and GI Pathology
- Liver Disease Diagnosis and Treatment
- Inflammatory Bowel Disease
- Gastric Cancer Management and Outcomes
- Metabolism and Genetic Disorders
- Phytochemical compounds biological activities
- Pancreatic and Hepatic Oncology Research
- Plant biochemistry and biosynthesis
- Renal function and acid-base balance
- Genomics, phytochemicals, and oxidative stress
- Pomegranate: compositions and health benefits
- Child Nutrition and Water Access
- MicroRNA in disease regulation
- Autophagy in Disease and Therapy
Central South University
2025
Chongqing Medical University
2025
Children's Hospital of Chongqing Medical University
2025
The First People's Hospital of Changde
2025
Nanjing University
2015-2024
Nanjing General Hospital of Nanjing Military Command
2015-2024
Nanjing Medical University
2015-2024
Nanjing Drum Tower Hospital
2023
Southern Medical University
2022
Shandong First Medical University
2021
The effect of and optimal timing for initiating supplemental parenteral nutrition (SPN) remain unclear after major abdominal surgery patients in whom energy targets cannot be met by enteral (EN) alone.To examine the early (E-SPN) (day 3 surgery) or late (L-SPN) 8 on incidence nosocomial infections undergoing who are at high nutritional risk have poor tolerance to EN.A multicenter randomized clinical trial was conducted from April 1, 2017, December 31, 2018, general department 11 tertiary...
Abstract Background Malnutrition and subsequent alterations in body composition (BC), particularly sarcopenia, are common but not yet elucidated patients with inflammatory bowel disease (IBD); we aimed to detail the changes BC characteristics of co‐occurrence malnutrition sarcopenia IBD investigate its effect on quality life. Methods This study was a multicentre, prospective, observational involving four tertiary referral hospitals China. The following data were collected from consecutive...
Luteolin (3',4',5,7-tetrahydroxyflavone) is a common dietary flavonoid, which has been demonstrated to exert anticancer effects in multiple cancer models. However, the detailed mechanisms underlying inhibitory effect of luteolin on glioblastoma cell metastasis remain poorly understood. The present study assessed U251MG and U87MG human lines. treatment significantly inhibited migration, this was associated with downregulated matrix metalloproteinase (MMP)‑2, MMP‑9 upregulated tissue inhibitor...
Recent studies have shown an association between atherogenic index of plasma (AIP) and nonalcoholic fatty liver disease (NAFLD), but the in a population pregnant women remains unclear. Our study aimed to examine AIP NAFLD Korean women. used publicly available data from Korea, which recruited singleton November 2014 September 2016 who were at 10-14 weeks gestation. The presence was diagnosed by ultrasound. calculated as log10 (TG/HDL). Participants grouped according tertile: T1 (< 0.16, n =...
Abstract Two homologous meroterpenoid gene clusters consisting of contiguous genes encoding polyketide synthase (PKS), prenyltransferase (PT), terpenoid cyclase (TC) and other tailoring enzymes were identified from two phylogenetically distinct fungi through computational analysis. Media optimization guided by reverse‐transcription PCR (RT‐PCR) enabled strains to produce eight new known meroterpenoids ( 1 – 10 ). Using inactivation, heterologous expression, biochemical analyses, we revealed...
Punicalagin induces apoptosis-independent autophagic cell death in BCPAP cells.
Patients with decompensated cirrhosis (DC) are prone to skeletal muscle loss, namely, sarcopenia, before liver transplantation (LT). While sarcopenia is reportedly associated adverse outcomes after LT, these findings limited owing mixed diseases and retrospective data. We investigated the association between 1-year overall survival (OS) in patients DC LT established validated a prediction model for postoperative OS based on sarcopenia.
This study was designed to investigate a relatively optimum dose of partial enteral nutrition (PEN) which effectively attenuates intestinal barrier dysfunction initiated by ischemia/reperfusion injury (IRI).In experiment 1, 60 male Sprague-Dawley (SD) rats were subjected IRI and assigned six groups according the different proportion EN administrations: namely total parenteral (TPN or 0%EN), 10%EN, 20%EN, 40%EN, 60%EN, (TEN 100%) groups, deficits intraluminal calorie supplemented PN. In 2, 50...
This study aimed to assess the prognostic value of Nutritional Risk Score 2002 (NRS2002) and patient-generated subjective global assessment (PG-SGA) for post-operative infections in patients with gastric cancer (GC) colorectal (CRC) who underwent curative surgery.This prospective included 1,493 GC 879 CRC surgery at 18 hospitals China between April 2017 March 2020. The NRS2002 PG-SGA were performed on day admission. relationship nutritional status before post-surgical incidence infection was...
Phomactin diterpenoids possess a unique bicyclo[9.3.1]pentadecane skeleton with multiple oxidative modifications, and are good platelet-activating factor (PAF) antagonists that can inhibit PAF-induced platelet aggregation. In this study, we identified the gene cluster (phm) responsible for biosynthesis of phomactins from marine fungus, Phoma sp. ATCC 74077. Despite complexity their structures, phomactin only requires two enzymes: type I diterpene cyclase PhmA P450 monooxygenase PhmC. was...
Aims Prevalence of malnutrition is a common and serious issue responsible for the morbidity mortality rate among hospitalized patients. We aimed to provide an actual comprehensive situation nutritional characteristics, support risk factors patients in China. Methods analyzed data from nutritionDay audit 2016 The international daylong cross-sectional survey was performed on November 10th, via filling out several questionnaires regarding information patients' illness, food intake history,...
Background Protein-energy malnutrition (PEM) can lead to growth hormone (GH) resistance. Leucine supplementation diets have been shown increase protein synthesis in muscles. Our study aimed at investigating if long-term leucine could modulate GH-insulin-like factor (IGF)-1 system function and mammalian target of rapamycin (mTOR)-related signal transduction skeletal muscles a rat model severe malnutrition. Methodology/Principal Findings Male Sprague-Dawley rats (n = 50; weight, 302 ± 5 g)...