A5047086401- Fatigue and fracture mechanics
- Welding Techniques and Residual Stresses
- Hydrogen embrittlement and corrosion behaviors in metals
- Structural Integrity and Reliability Analysis
- Microstructure and Mechanical Properties of Steels
- Mechanical stress and fatigue analysis
- Clinical Nutrition and Gastroenterology
- Nutrition and Health in Aging
- Material Properties and Failure Mechanisms
- Enhanced Recovery After Surgery
- Metallurgy and Material Forming
- RNA modifications and cancer
- Immune Cell Function and Interaction
- Cancer-related gene regulation
- Epigenetics and DNA Methylation
- Non-Destructive Testing Techniques
- Abdominal Surgery and Complications
- Bladder and Urothelial Cancer Treatments
- Remote-Sensing Image Classification
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Renal cell carcinoma treatment
- Urinary and Genital Oncology Studies
- Laser and Thermal Forming Techniques
- Metal Forming Simulation Techniques
Harbin Medical University
2015-2025
Second Affiliated Hospital of Harbin Medical University
2013-2025
China National Petroleum Corporation (China)
2015-2024
Chengde Medical University
2017-2024
Qilu University of Technology
2021-2023
First Affiliated Hospital of Nanchang University
2023
Nanchang University
2023
Affiliated Hospital of Chengde Medical College
2016-2022
Shandong Academy of Sciences
2021-2022
Beijing Friendship Hospital
2016
Methyltransferase-like 1 (METTL1) mediated 7-methylguanosine (m7G) is crucial for the regulation of chemoresistance in cancer treatment. However, role METTL1 regulating colon (CC) cells to cisplatin still unclear. This study established cisplatin-resistant CC (CR-CC) and found that was low-expressed CR-CC compared their paired cisplatin-sensitive (CS-CC) cells. Besides, overexpressed enhanced cytotoxic effects on In addition, miR-149-3p downstream target METTL1, which could be positively...
The effect of and optimal timing for initiating supplemental parenteral nutrition (SPN) remain unclear after major abdominal surgery patients in whom energy targets cannot be met by enteral (EN) alone.To examine the early (E-SPN) (day 3 surgery) or late (L-SPN) 8 on incidence nosocomial infections undergoing who are at high nutritional risk have poor tolerance to EN.A multicenter randomized clinical trial was conducted from April 1, 2017, December 31, 2018, general department 11 tertiary...
Nutrition assessment enables early identification of malnourished patients and those at risk malnutrition. To determine the prevalence malnutrition, to analyze correlation between short-form Mini Nutritional Assessment (MNA-SF) Risk Screening 2002 (NRS2002) with classical nutritional markers among elderly hospitalized in surgery departments, a view improving nutrition advice for these patients. A total 142 admitted were enrolled study. Within 48 hours admission, MNA-SF NRS2002 scale,...
This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). retracted at the request of Editor-in-Chief. Concern was raised by a reader that pictures different cell lines in Fig. 3A and 4D were from same line, suggesting repeated use picture. The editor contacted corresponding author for explanation, but there no reply. Apologies are offered to readers journal this not detected during submission process.
Abstract Endogenous transfer RNA‐derived small RNAs (tsRNAs) are newly identified that closely associated with the pathogenesis of multiple diseases, but involvement tsRNAs in regulating acute pancreatitis (AP) development has not been reported. In this study, we screened out a novel tsRNA, tRF3‐Thr‐AGT, was aberrantly downregulated acinar cell line AR42J treated sodium taurocholate (STC) and pancreatic tissues STC‐induced AP rat models. addition, STC treatment suppressed viability, induced...
Abstract CYP24A1 and CYP27B1 are critical genes determining 1α,25(OH) 2 D 3 concentration impacting on carcinogenesis. A case–control study including 528 colorectal cancer (CRC) patients 605 cancer-free controls a follow-up with 317 cases were conducted in northeast China. Genotypes tested by TaqMan Genotyping Assays. Individuals carrying the GG genotype of G > T (rs10877012) exhibited decreased CRC risk compared those TT (OR adjusted adj ) = 0.57, 95% Confidence Interval (CI) 0.38–0.84)....
Using deep learning to classify hyperspectral image(HSI) with only a few labeled samples available is challenge. Recently, the knowledge distillation method based on soft label generation has been used solve classification problems limited number of samples. Unlike normal labels, labels are considered probability sample belonging certain category, and therefore more informative for sake classification. The existing methods HSI cannot fully exploit information unlabeled To this problem, we...
This study aimed to assess the prognostic value of Nutritional Risk Score 2002 (NRS2002) and patient-generated subjective global assessment (PG-SGA) for post-operative infections in patients with gastric cancer (GC) colorectal (CRC) who underwent curative surgery.This prospective included 1,493 GC 879 CRC surgery at 18 hospitals China between April 2017 March 2020. The NRS2002 PG-SGA were performed on day admission. relationship nutritional status before post-surgical incidence infection was...
Bladder cancer (BLCA) is an urogenital system tumor with a high morbidity. We aimed to explore the function and potential mechanism of α-E-catenin (CTNNA1) in BLCA.The CTNNA1 expression BLCA tissues was detected using qRT-PCR immunohistochemistry. QRT-PCR Western blot were performed measure cell lines. up-regulated T24 UMUC-2 cells by overexpression plasmid transfection. Cell proliferation, apoptosis, migration invasion respectively assessed CCK-8 assay, flow cytometry, wound healing assay...
Methylation status plays a causal role in carcinogenesis targeted tissues. However, the relationship between DNA methylation of multiple genes blood leukocytes and colorectal cancer (CRC) susceptibility as well interactions dietary factors CRC risks are unclear. We performed case-control study with 466 patients 507 cancer-free controls to investigate association among individual genes, CpG site (MCSM), heterogeneous susceptibility. Peripheral levels were detected by performing...
In our previous paper, we demonstrated that Connexin 43 (CX43) was highly expressed in bladder cancer (BC) tissues. But the molecular mechanism about microRNAs (miRNAs) regulation upstream of CX43 BC has not been well elucidated and remains to be further studied. MicroRNA-139-5p (miR-139-5p) is a tumor suppressor progression multifarious cancers including BC. Nevertheless, underlying mechanisms CX43/miR-139-5p tumorigenesis are still illustrated. The specific objective study inquiry effect...
Background: The effect of early achievement energy targets using different nutritional support strategies in patients undergoing major abdominal surgery is unclear. This study determined the impact on incidence nosocomial infections surgery. Methods: was a secondary analysis two open-label randomized clinical trials. Patients from general department 11 academic hospitals China and at risk (Nutritional screening 2002≥3) were divided into groups based whether they met 70% targets, target (521...