A5020503194- Pancreatitis Pathology and Treatment
- Pancreatic and Hepatic Oncology Research
- Gastrointestinal disorders and treatments
- Gastrointestinal Tumor Research and Treatment
- Gastric Cancer Management and Outcomes
- Esophageal and GI Pathology
- Gut microbiota and health
- Liver Disease Diagnosis and Treatment
- IgG4-Related and Inflammatory Diseases
- Plant Disease Management Techniques
- Gastrointestinal motility and disorders
- Renal Diseases and Glomerulopathies
- Neuroendocrine Tumor Research Advances
- Acupuncture Treatment Research Studies
- Heavy Metal Exposure and Toxicity
- Complementary and Alternative Medicine Studies
- Clostridium difficile and Clostridium perfringens research
- Plant responses to water stress
- Genetic and Kidney Cyst Diseases
- Soybean genetics and cultivation
- Chronic Kidney Disease and Diabetes
- Healthcare and Venom Research
- Agroforestry and silvopastoral systems
- Plant Pathogens and Fungal Diseases
- Abdominal vascular conditions and treatments
Second Military Medical University
2011-2025
Changhai Hospital
2011-2025
Ningbo Product Quality Supervision and Inspection Institute
2024
Soochow University
2022-2024
Wenzhou Medical University
2024
Zhejiang Taizhou Hospital
2024
Chongqing Medical University
2024
The Affiliated Yongchuan Hospital of Chongqing Medical University
2024
Shanghai Institute of Hematology
2024
Southeast University
2020-2023
Obesity is a global epidemic in the industrialized and developing world, many children suffer from obesity-related complications. Gut microbiota dysbiosis might have significant effect on development of obesity. The continues to develop through childhood thus may be prime time for interventions realize health promotion or disease prevention. Therefore, it crucial understand structure function pediatric gut microbiota.According inclusion criteria exclusion criteria, twenty-three normal weight...
Background The negative predictive value of endoscopic ultrasonography-guided fine needle aspiration for the diagnosis solid pancreatic lesions remains low, and biopsy specimens are sometimes inadequate appropriate pathological diagnosis. Aims To evaluate usefulness a novel method contrast-enhanced harmonic fine-needle differential adequate sampling lesions. Methods Patients with who underwent guided by ultrasonography or from October 2010 to July 2013 were retrospectively identified...
Abstract Autoimmune pancreatitis (AIP) is identified as a severe chronic immune‐related disorder in pancreas, including two subtypes. In this study, pancreatic lesions patients diagnosed either type 1 AIP or 2 are examined, and these patients’ peripheral blood at single‐cell level. Furthermore, flow cytometry, immunofluorescence, functional assays performed to verify the cell AIP, there notable increase amount of B cells plasma cells, IgG4+ key pathogenic AIP. The differentiation path...
Genetic alterations may contribute to chronic pancreatitis (CP) in Chinese young patients. This study was designed investigate mutations of cationic trypsinogen (PRSS1), pancreatic secretory trypsin inhibitor or serine protease Kazal type 1 (SPINK1), cystic fibrosis transmembrane conductance regulator (CFTR), chymotrypsin C (CTRC) and CLDN2 genes the copy number variations (CNVs) PRSS1 asses associations with development idiopathic CP (ICP) children.Retrospective.A single center.75 ICP...
Abstract Chronic pancreatitis (CP) is an inflammatory disease characterized by progressive fibrosis of pancreas. Early diagnosis will improve the prognosis patients. This study aimed to obtain serum miRNA biomarkers for early CP. In current study, we analyzed differentially expressed miRNAs (DEmiRs) CP patients from Gene Expression Omnibus (GEO), and DEmiRs in plasma (n = 10) clinic microarrays. levels were further tested clinical samples including 20), late 20) healthy controls 18). The...
This study was conducted to assess the effect of mixed isoacid (MI) supplementation on fermentation characteristics, nutrient apparent digestibility, growth performance, and rumen bacterial community in yaks. A 72-h vitro experiment performed an ANKOM RF gas production system. MI added five treatments at doses 0, 0.1%, 0.2%, 0.3%, 0.4%, 0.5% dry matter (DM) basis substrates using a total 26 bottles (4 per treatment 2 as blank). Cumulative measured 4, 8, 16, 24, 36, 48, 72 h. Fermentation...
Background Childhood obesity constitutes a worldwide health problem, and the gut microbiota play extremely important roles in obesity. Herein, we aimed to characterize children of normal weight, overweight, Methods Thirty 35 who were with enrolled from Nanjing, China. We isolated DNA fecal samples, employed 16S rRNA gene sequencing explore diversity composition microbiota. Results The operational taxonomic unit (OTU) numbers exhibited reduction abundance increase body weight. Alpha analysis...
Cardiovascular disease, which is mainly caused by coronary atherosclerosis, one of the leading causes death and disability worldwide. Gut microbiota likely play an important role in atherosclerosis. This study aims to investigate profile adults with atherosclerosis provide a theoretical basis for future research.Fecal samples were collected from 35 adult patients diagnosed 32 healthy Nanjing, China, V3-V4 region 16S rDNA genes was sequenced using high-throughput sequencing. Differences alpha...
Abstract Background and Aim Incidental pancreatic cystic lesions (PCLs) are being diagnosed more frequently. However, little is known about the prevalence of PCLs in Chinese population. The aim study was to assess crude individuals who underwent magnetic resonance imaging (MRI). Methods Data from consecutive patients MRI without indications were included. images reviewed for presence cysts. high‐risk different gender age groups calculated. To prevalence, demographic data standardized on...
Objectives: The α-tocopherol and tocotrienol-rich fraction (TRF) are considered effective antioxidants. This study aimed to compare the antioxidative antifibrotic effects of TFR in dibutylin dichloride (DBTC)-induced chronic pancreatitis (CP) rats. Methods: Oral administration (both 800 mg/kg per day) started next day after DBTC (8 mg/kg) infusion into tail vein for 4 weeks. Histological examination, Sirius red staining, measurement contents hydroxyproline malondialdehyde pancreas were...
Sinew acupuncture is a new modality of in which needles are inserted into acupoints, ashi points or spasm sinew and muscles along the meridian pathway. A previous observational study revealed that has immediate analgesic effects on various soft tissue injuries, including knee injuries. However, no rigorous trials have been conducted. This aims to examine whether can safely relieve pain symptoms osteoarthritis (KOA) improve patients' functional movement quality life.
<b><i>Aim:</i></b> To investigate the relationship between hemoglobin levels and progression of IgA nephropathy (IgAN). <b><i>Methods:</i></b> In a two-center cohort 1,828 cases with biopsy-proven IgAN, we examined association primary outcome composite all-cause mortality or kidney failure defined as 40% decline in eGFR, ESKD (defined eGFR &#x3c;15 mL/min/1.73 m<sup>2</sup> need for replacement therapy including hemodialysis,...
BACKGROUND:Guidelines recommend a clear liquid fasting time of 2 h before surgery, which is often exceeded, leading to adverse reactions (ARs) such as discomfort, thirst, and dehydration. We assessed the gastric contents ARs after oral glucose water administration 1 prior surgery in children with cyanotic congenital heart disease (CCHD). MATERIAL AND METHODS:This was non-inferiority randomized controlled trial CCHD enrolled at Fujian Medical University Union Hospital from 09/2014 05/2017...
Validation of serum tumor biomarkers in predicting advanced cystic mucinous neoplasm the pancreas
This study reports the toxicity of Pb exposure on systemic inflammation in high-fat-diet (HFD) mice and potential mechanisms. Results indicated that exacerbated intestinal barrier damage increased serum levels lipopolysaccharide (LPS) diamine oxidase HFD mice. Elevated LPS activates colonic ileal LPS-TLR4 inflammatory signaling pathway further induces hepatic adipose expression. The 16S rRNA gene sequencing results showed promoted abundance potentially harmful LPS-producing bacteria such as...
OBJECTIVE Acute gastric or intestinal spasm‐like pain is common in clinical setting. Hyoscine butylbromide (HBB), an anti‐cholinergic agent, relieves stomach and bowel cramps by inhibiting smooth muscle contractility. In this study, we aimed to compare the efficacy safety of parenteral HBB anisodamine for treating acute pain. METHODS randomized, controlled, double‐blind, parallel‐group, multicenter non‐inferiority trial, 299 Chinese patients were randomly assigned a ratio 1:1. They...
Background This study aimed to compare the clinical outcomes between submucosal tunneling endoscopic resection (STER) and dissection (ESD) for large subepithelial esophageal lesions (SELs) analyze risk factors perforation piecemeal resection.Methods The clinicopathological features of treatment 56 patients with SELs diameters ≥30 mm, diagnosed June 2017 December 2020, were reviewed in this retrospective cohort study. Patients divided into two groups (ESD group STER group).Results complete...